Zobrazeno 1 - 8
of 8
pro vyhledávání: '"P. R., Dormitzer"'
BNT162b2-elicited neutralization of Delta plus, Lambda, Mu, B.1.1.519, and Theta SARS-CoV-2 variants
Autor:
Jianying Liu, Yang Liu, Hongjie Xia, Jing Zou, Scott C. Weaver, Kena A. Swanson, Hui Cai, Mark Cutler, David Cooper, Alexander Muik, Kathrin U. Jansen, Ugur Sahin, Xuping Xie, Philip R. Dormitzer, Pei-Yong Shi
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-4 (2022)
Abstract BNT162b2-elicited human sera neutralize the currently dominant Delta SARS-CoV-2 variant. Here, we report the ability of 20 human sera, drawn 2 or 4 weeks after two doses of BNT162b2, to neutralize USA-WA1/2020 SARS-CoV-2 bearing variant spik
Externí odkaz:
https://doaj.org/article/d1191565f6484c56a7a3a8d7ac73402e
Autor:
Kathrin Leppek, Gun Woo Byeon, Wipapat Kladwang, Hannah K. Wayment-Steele, Craig H. Kerr, Adele F. Xu, Do Soon Kim, Ved V. Topkar, Christian Choe, Daphna Rothschild, Gerald C. Tiu, Roger Wellington-Oguri, Kotaro Fujii, Eesha Sharma, Andrew M. Watkins, John J. Nicol, Jonathan Romano, Bojan Tunguz, Fernando Diaz, Hui Cai, Pengbo Guo, Jiewei Wu, Fanyu Meng, Shuai Shi, Eterna Participants, Philip R. Dormitzer, Alicia Solórzano, Maria Barna, Rhiju Das
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
The authors develop an RNA sequencing-based platform, PERSIST-seq, to simultaneously delineate in-cell mRNA stability, ribosome load, and in-solution stability of a diverse mRNA library to derive design principles for improved mRNA therapeutics.
Externí odkaz:
https://doaj.org/article/2d3b8c62fa5e4b1aa2f3fa11c8674939
Autor:
Miwa Haranaka, James Baber, Yoichiro Ogama, Masako Yamaji, Masakazu Aizawa, Osamu Kogawara, Ingrid Scully, Eleni Lagkadinou, Ӧzlem Türeci, Uğur Şahin, Philip R. Dormitzer, William C. Gruber, Stephen Lockhart
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Here the authors provide the interim analysis of an ongoing phase 1/2 study of the BNT162b2 vaccine in healthy Japanese adults. They report mainly mild to moderate local reactions and no serious adverse events as well as good antibody induction one m
Externí odkaz:
https://doaj.org/article/b46c9a1d119e4f05b2b58be147b5baa4
Autor:
Jing Zou, Xuping Xie, Camila R. Fontes-Garfias, Kena A. Swanson, Isis Kanevsky, Kristin Tompkins, Mark Cutler, David Cooper, Philip R. Dormitzer, Pei-Yong Shi
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-4 (2021)
Abstract Initial COVID-19 vaccine candidates were based on the original sequence of SARS-CoV-2. However, the virus has since accumulated mutations, among which the spike D614G is dominant in circulating virus, raising questions about potential virus
Externí odkaz:
https://doaj.org/article/ec866784239c40d8b7031906e2ca7586
Autor:
Takako Tabata, Matthew Petitt, Julia Li, Xiaoyuan Chi, Wei Chen, Irina Yurgelonis, Sabine Wellnitz, Simon Bredl, Tiago Vicente, Xinzhen Yang, Philip R. Dormitzer, Lenore Pereira
Publikováno v:
Vaccines, Vol 10, Iss 7, p 1074 (2022)
Human cytomegalovirus (HCMV) is the leading viral cause of congenital disease and permanent birth defects worldwide. Although the development of an effective vaccine is a public health priority, no vaccines are approved. Among the major antigenic tar
Externí odkaz:
https://doaj.org/article/a9fe1dd7c80347e59dea44338fb8e75d
Autor:
Rhiannon R. Penkert, Sumana Chandramouli, Philip R. Dormitzer, Ethan C. Settembre, Robert E. Sealy, Susan Wong, Neal S. Young, Yilun Sun, Li Tang, Alyssa Cotton, Jola Dowdy, Randall T. Hayden, Jane S. Hankins, Julia L. Hurwitz
Publikováno v:
Vaccines, Vol 9, Iss 8, p 860 (2021)
Children with sickle cell disease (SCD) suffer life-threatening transient aplastic crisis (TAC) when infected with parvovirus B19. In utero, infection of healthy fetuses may result in anemia, hydrops, and death. Unfortunately, although promising vacc
Externí odkaz:
https://doaj.org/article/f7f113713a25483684b72228951921e3
Autor:
I., Dieussaert, J. H., Kim, S., Luik, C., Seidl, W., Pu, J. U., Stegmann, G. K., Swamy, P., Webster, P. R., Dormitzer
Publikováno v:
Obstetric Anesthesia Digest; Sep2024, Vol. 44 Issue 3, p138-138, 1/2p
Autor:
Keith L. Williams, J M Miller, Harry B. Greenberg, Kerry R. Emslie, P R Dormitzer, Martin B. Slade
Publikováno v:
Journal of Virology. 69:1747-1754
The outer capsid protein of rotavirus, VP7, is a major neutralization antigen and is considered a necessary component of any subunit vaccine developed against rotavirus infection. For this reason, significant effort has been directed towards producin