Zobrazeno 1 - 10
of 359
pro vyhledávání: '"P. Podini"'
Autor:
Mattia Zaghi, Fabiana Longo, Luca Massimino, Alicia Rubio, Simone Bido, Pietro Giuseppe Mazzara, Edoardo Bellini, Federica Banfi, Paola Podini, Francesca Maltecca, Alessio Zippo, Vania Broccoli, Alessandro Sessa
Publikováno v:
Molecular Autism, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Background Neurodevelopmental disorders (NDDs) are heterogeneous conditions due to alterations of a variety of molecular mechanisms and cell dysfunctions. SETD5 haploinsufficiency leads to NDDs due to chromatin defects. Epigenetic basis of N
Externí odkaz:
https://doaj.org/article/41a9f2cb20ba4eb3b3a5cb5d759d70b4
Autor:
Alessandra Pisciottani, Laura Croci, Fabio Lauria, Chiara Marullo, Elisa Savino, Alessandro Ambrosi, Paola Podini, Marta Marchioretto, Filippo Casoni, Ottavio Cremona, Stefano Taverna, Angelo Quattrini, Jean-Michel Cioni, Gabriella Viero, Franca Codazzi, G. Giacomo Consalez
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Amyotrophic lateral sclerosis (ALS) is a progressive, lethal neurodegenerative disease mostly affecting people around 50–60 years of age. TDP-43, an RNA-binding protein involved in pre-mRNA splicing and controlling mRNA stability and translation, f
Externí odkaz:
https://doaj.org/article/f1fe9f46351d48d3b738db03ec8c4c64
Akademický článek
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Autor:
Andrea Del Bondio, Fabiana Longo, Daniele De Ritis, Erica Spirito, Paola Podini, Bernard Brais, Angela Bachi, Angelo Quattrini, Francesca Maltecca
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is caused by mutations in SACS gene encoding sacsin, a huge protein highly expressed in cerebellar Purkinje cells (PCs). Patients with ARSACS, as well as mouse models, display early d
Externí odkaz:
https://doaj.org/article/bcad322e3a554a7182f2f20cc1132d8b
Autor:
Angela Genchi, Aurora Semerano, Ghil Schwarz, Beatrice Dell’Acqua, Giorgia Serena Gullotta, Michela Sampaolo, Enzo Boeri, Angelo Quattrini, Francesca Sanvito, Susanna Diamanti, Andrea Bergamaschi, Stefano Grassi, Paola Podini, Pietro Panni, Caterina Michelozzi, Franco Simionato, Francesco Scomazzoni, Paolo Remida, Luca Valvassori, Andrea Falini, Carlo Ferrarese, Patrik Michel, Guillaume Saliou, Steven Hajdu, Simone Beretta, Luisa Roveri, Massimo Filippi, Davide Strambo, Gianvito Martino, Marco Bacigaluppi
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract Coronavirus disease 2019 (COVID-19) is associated with an increased risk of thrombotic events. Ischemic stroke in COVID-19 patients entails high severity and mortality rates. Here we aimed to analyze cerebral thrombi of COVID-19 patients wit
Externí odkaz:
https://doaj.org/article/0e50d475d0ca431b91f15a7675227609
Autor:
Federica Cerri, Francesco Gentile, Ferdinando Clarelli, Silvia Santoro, Yuri Matteo Falzone, Giorgia Dina, Alessandro Romano, Teuta Domi, Laura Pozzi, Raffaella Fazio, Paola Podini, Melissa Sorosina, Paola Carrera, Federica Esposito, Nilo Riva, Chiara Briani, Tiziana Cavallaro, Massimo Filippi, Angelo Quattrini
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Although inflammation appears to play a role in neurolymphomatosis (NL), the mechanisms leading to degeneration in the peripheral nervous system are poorly understood. The purpose of this exploratory study was to identify molecular pathways underlyin
Externí odkaz:
https://doaj.org/article/cc6f17e7176d4a779b5afbb6b7aa98d8
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Pietro Giuseppe Mazzara, Sharon Muggeo, Mirko Luoni, Luca Massimino, Mattia Zaghi, Parisa Tajalli-Tehrani Valverde, Simone Brusco, Matteo Jacopo Marzi, Cecilia Palma, Gaia Colasante, Angelo Iannielli, Marianna Paulis, Chiara Cordiglieri, Serena Gea Giannelli, Paola Podini, Cinzia Gellera, Franco Taroni, Francesco Nicassio, Marco Rasponi, Vania Broccoli
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Friedreich’s ataxia (FRDA) is an autosomal-recessive disorder. Here the authors describe a DRG organoid from patient derived-neurons and co-culture with muscle cells to mimic the disorder in vitro and demonstrate potential correction of the phenoty
Externí odkaz:
https://doaj.org/article/b91a2f099cbf40dd993de29571b96be7
Autor:
Stefano Gelibter, Giulia Marostica, Alessandra Mandelli, Stella Siciliani, Paola Podini, Annamaria Finardi, Roberto Furlan
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 2, Pp n/a-n/a (2022)
Abstract Mounting evidence suggests that storage has an impact on extracellular vesicles (EVs) properties. While −80°C storage is a widespread approach, some authors proposed improved storage strategies with conflicting results. Here, we designed
Externí odkaz:
https://doaj.org/article/687a62a4c8e54021a9cabb83757c69b5
Akademický článek
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