Zobrazeno 1 - 10
of 642
pro vyhledávání: '"P. O'Hern"'
Externally driven dense packings of particles can exhibit nonlinear wave phenomena that are not described by effective medium theory or linearized approximate models. Such nontrivial wave responses can be exploited to design sound-focusing/scrambling
Externí odkaz:
http://arxiv.org/abs/2411.15142
Autor:
Viswanath, Siddharth, Bhaskar, Dhananjay, Johnson, David R., Rocha, Joao Felipe, Castro, Egbert, Grady, Jackson D., Grigas, Alex T., Perlmutter, Michael A., O'Hern, Corey S., Krishnaswamy, Smita
Understanding the dynamic nature of protein structures is essential for comprehending their biological functions. While significant progress has been made in predicting static folded structures, modeling protein motions on microsecond to millisecond
Externí odkaz:
http://arxiv.org/abs/2410.20317
Autor:
Sumner, Jacob, Meng, Grace, Brandt, Naomi, Grigas, Alex T., Córdoba, Andrés, Shattuck, Mark D., O'Hern, Corey S.
A goal of computational studies of protein-protein interfaces (PPIs) is to predict the binding site between two monomers that form a heterodimer. The simplest version of this problem is to rigidly re-dock the bound forms of the monomers, which involv
Externí odkaz:
http://arxiv.org/abs/2407.16580
Autor:
Cheng, Yuxuan, Lonial, Benjamin F., Sista, Shivnag, Meer, David J., Hofert, Anisa, Weeks, Eric R., Shattuck, Mark D., O'Hern, Corey S.
Publikováno v:
Soft Matter 20 (2024) 8036
Capillary droplets form due to surface tension when two immiscible fluids are mixed. We describe the motion of gravity-driven capillary droplets flowing through narrow constrictions and obstacle arrays in both simulations and experiments. Our new cap
Externí odkaz:
http://arxiv.org/abs/2406.13776
Proteins fold to a specific functional conformation with a densely packed hydrophobic core that controls their stability. We develop a geometric, yet all-atom model for proteins that explains the universal core packing fraction of $\phi_c=0.55$ found
Externí odkaz:
http://arxiv.org/abs/2405.09646
Autor:
Liu, Zhuoyi, Grigas, Alex T., Sumner, Jacob, Knab, Edward, Davis, Caitlin M., O'Hern, Corey S.
Proteins naturally occur in crowded cellular environments and interact with other proteins, nucleic acids, and organelles. Since most previous experimental protein structure determination techniques require that proteins occur in idealized, non-physi
Externí odkaz:
http://arxiv.org/abs/2405.07983
There is growing interest in engineering unconventional computing devices that leverage the intrinsic dynamics of physical substrates to perform fast and energy-efficient computations. Granular metamaterials are one such substrate that has emerged as
Externí odkaz:
http://arxiv.org/abs/2404.04825
Autor:
Zheng, Yitong, Wang, Dong, Beeghly, Garrett, Fischbach, Claudia, Shattuck, Mark D., O'Hern, Corey S.
Publikováno v:
APL Bioengineering 8 (2024) 036104
Breast cancer invasion into adipose tissue strongly influences disease progression and metastasis. The degree of cancer cell invasion into adipose tissue depends on numerous biochemical and physical properties of cancer cells, adipocytes, and other k
Externí odkaz:
http://arxiv.org/abs/2403.12293
Autor:
Maisuradze, Luka, King, Megan C., Surovtsev, Ivan V., Mochrie, Simon G. J., Shattuck, Mark D., O'Hern, Corey S.
Publikováno v:
PLoS Computational Biology 20 (2024) e1012221
Chromatin is a polymer complex of DNA and proteins that regulates gene expression. The three-dimensional structure and organization of chromatin controls DNA transcription and replication. High-throughput chromatin conformation capture techniques gen
Externí odkaz:
http://arxiv.org/abs/2312.14342
Publikováno v:
ACS omega 9.9 (2024) 10286-10298
The mechanical properties of Cu-Ti alloys have been characterized extensively through experimental studies. However, a detailed understanding of why the strength of Cu increases after a small fraction of Ti atoms is added to the alloy is still missin
Externí odkaz:
http://arxiv.org/abs/2310.05415