Zobrazeno 1 - 10
of 15
pro vyhledávání: '"P. N. Vikhreva"'
Autor:
Elena Kulakovskaya, Murad D. Mollaev, P. N. Vikhreva, Sergey Larin, Dmitriy M. Chudakov, A. V. Kibardin, Michael Maschan, Dmitry Pershin, Varvara Maiorova
Publikováno v:
Vaccines
Vaccines, Vol 9, Iss 1238, p 1238 (2021)
Volume 9
Issue 11
Vaccines, Vol 9, Iss 1238, p 1238 (2021)
Volume 9
Issue 11
Relapsed/refractory acute myeloid leukemia (AML) cannot be cured with chemotherapy alone, as the blasts survive the treatment. Chimeric antigen receptor (CAR) approaches for AML are being actively developed. CARs promote immune reactions through reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1f726cb841ea528e9d9cbcb45427f0
https://pubmed.ncbi.nlm.nih.gov/34835169
https://pubmed.ncbi.nlm.nih.gov/34835169
Publikováno v:
Acta Naturae. 9:66-73
describe a novel hybrid tumor-specific promoter, ARE-hTERT, composed of the human TERT gene promoter (hTERT) and the antioxidant response element (ARE) from the human GCLM gene promoter. The hybrid promoter retains the tumor specificity of the basal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fd07714b033a27ffa071db2c3a0a407
https://doi.org/10.32607/20758251-2017-9-4-66-73
https://doi.org/10.32607/20758251-2017-9-4-66-73
Autor:
Mara Mancini, P. N. Vikhreva, Varvara Petrova, Ivano Amelio, Ilias Pestlikis, Tarik Gokbulut, Gerry Melino, Nicola Di Daniele, Richard A. Knight
Publikováno v:
Biochemical and Biophysical Research Communications
p73 is a transcription factor belonging to the p53 tumour suppressor family. p73−/− mice exhibit a range of phenotypes including neurological, reproductive and inflammatory defects. Although the role of p73 in the control of genomic stability exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2b25e7dcb5d5f94768d773bc19336a
https://doi.org/10.1016/j.bbrc.2016.10.085
https://doi.org/10.1016/j.bbrc.2016.10.085
Selection of microRNA for providing tumor specificity of transgene expression in cancer gene therapy
Publikováno v:
Molecular Biology. 50:284-291
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70db5a052e43ebe0a4659ba43cd242e7
https://doi.org/10.1134/s0026893316020229
https://doi.org/10.1134/s0026893316020229
Autor:
Ivano Amelio, Richard A. Knight, Nicolai Barlev, Ningxia Xie, Margherita Annicchiarico-Petruzzelli, Gerry Melino, P. N. Vikhreva
As a member of p53 family, p73 has attracted intense investigations due to its structural and functional similarities to p53. Among more than ten p73 variants, the transactivation (TA) domain-containing isoform TAp73 is the one that imitates the p53'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96e3df7f09339f370c81223b27451f0
https://europepmc.org/articles/PMC5969564/
https://europepmc.org/articles/PMC5969564/
Выбор микроРНК для обеспечения опухолевой специфичности экспрессии трансгена при генной терапии рака
Publikováno v:
Молекулярная биология. 50:327-335
The use of tumor-specific microRNA loss to inhibit transgene expression in normal cells is considered as a way to increase the specificity of gene-therapeutic antitumor drugs. This method assumes the introduction of recognition sites of suppressed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84d88b85e74623e0400691dc478122ab
https://doi.org/10.7868/s0026898416020221
https://doi.org/10.7868/s0026898416020221
Publikováno v:
Cell cycle (Georgetown, Tex.). 16(19)
Programmed cell death 4 (Pdcd4) is frequently suppressed in tumors of various origins and its suppression correlates with tumor progression. Pdcd4 inhibits cap-dependent translation from mRNAs with highly structured 5'-regions through interaction wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38cd5425b11fcb1ee5574fb9b9767497
https://pubmed.ncbi.nlm.nih.gov/28853972
https://pubmed.ncbi.nlm.nih.gov/28853972
Autor:
Georgii P. Georgiev, Sergei Tillib, P. N. Vikhreva, E. Yu. Lyssuk, N. V. Gnuchev, Sergey Larin, E. V. Korobko, Igor V. Korobko, A. V. Kibardin, Tatiana I. Ivanova
Publikováno v:
Biochemistry (Moscow). 77:659-665
Nanoantibodies (single-domain antibodies, nanobodies) derived from noncanonical single-chain immunoglobulins provide an attractive tool for in vitro and in vivo diagnostics as well as for development of targeted drugs for clinical use. Nanoantibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c83eb97d4752b56f4b32cd60b26f99f
https://doi.org/10.1134/s0006297912060132
https://doi.org/10.1134/s0006297912060132
Publikováno v:
Molekuliarnaia biologiia. 50(2)
The use of tumor-specific microRNA loss to inhibit transgene expression in normal cells is considered as a way to increase the specificity of gene-therapeutic antitumor drugs. This method assumes the introduction of recognition sites of suppressed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea004ed069568ca726a9b036930d0803
https://pubmed.ncbi.nlm.nih.gov/27239854
https://pubmed.ncbi.nlm.nih.gov/27239854
Publikováno v:
Doklady Biochemistry and Biophysics. 429:323-325
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9259b978160776d734301ce4cb3d01e0
https://doi.org/10.1134/s160767290906009x
https://doi.org/10.1134/s160767290906009x