Zobrazeno 1 - 9
of 9
pro vyhledávání: '"P. N. Solyev"'
Autor:
Irina A. Bychek, Anastasia A. Zenchenko, Maria A. Kostromina, Marat M. Khisamov, Pavel N. Solyev, Roman S. Esipov, Sergey N. Mikhailov, Irina V. Varizhuk
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1069 (2024)
The enzymatic synthesis of nucleoside derivatives is an important alternative to multi-step chemical methods traditionally used for this purpose. Despite several undeniable advantages of the enzymatic approach, there are a number of factors limiting
Externí odkaz:
https://doaj.org/article/72697b09fb0e4f97ab3e3b61f244b639
Publikováno v:
Antibiotics, Vol 12, Iss 5, p 894 (2023)
A significant increase of microbial resistance to glycopeptides (especially vancomycin-resistant enterococci and Staphylococcus aureus) prompted researchers to design new semisynthetic glycopeptide derivatives, such as dual-action antibiotics that co
Externí odkaz:
https://doaj.org/article/1ea4532cf3e04970acb86dd876501600
Autor:
Konstantin V. Potapov, Roman A. Novikov, Maxim A. Novikov, Pavel N. Solyev, Yury V. Tomilov, Sergey N. Kochetkov, Alexander A. Makarov, Vladimir A. Mitkevich
Publikováno v:
Molecules, Vol 28, Iss 8, p 3568 (2023)
Bacterial cystathionine γ-lyase (bCSE) is the main producer of H2S in pathogenic bacteria such as Staphylococcus aureus, Pseudomonas aeruginosa, etc. The suppression of bCSE activity considerably enhances the sensitivity of bacteria to antibiotics.
Externí odkaz:
https://doaj.org/article/62897d7ae169496ead6c6bfef87fcff0
Autor:
Konstantin V. Potapov, Roman A. Novikov, Pavel N. Solyev, Sergey N. Kochetkov, Alexander A. Makarov, Vladimir A. Mitkevich
Publikováno v:
Molecules, Vol 27, Iss 21, p 7534 (2022)
Heptose phosphates—unique linkers between endotoxic lipid A and O-antigen in the bacterial membrane—are pathogen-associated molecular patterns recognized by the receptors of the innate immune system. Understanding the mechanisms of immune system
Externí odkaz:
https://doaj.org/article/91759e50c9514912a47147529b7b0829
Autor:
Anastasia L. Khandazhinskaya, Elena S. Matyugina, Pavel N. Solyev, Maggie Wilkinson, Karen W. Buckheit, Robert W. Buckheit, Larisa N. Chernousova, Tatiana G. Smirnova, Sofya N. Andreevskaya, Khalid J. Alzahrani, Manal J. Natto, Sergey N. Kochetkov, Harry P. de Koning, Katherine L. Seley-Radtke
Publikováno v:
Molecules, Vol 24, Iss 19, p 3433 (2019)
Carbocyclic nucleosides have long played a role in antiviral, antiparasitic, and antibacterial therapies. Recent results from our laboratories from two structurally related scaffolds have shown promising activity against both Mycobacterium tuberculos
Externí odkaz:
https://doaj.org/article/a637c58484344774bb35089123f966d7
Autor:
S. D. Negrya, M. V. Jasko, D. A. Makarov, P. N. Solyev, I. L. Karpenko, O. V. Shevchenko, O. V. Chekhov, A. A. Glukhova, B. F. Vasilyeva, T. A. Efimenko, I. G. Sumarukova, O. V. Efremenkova, S. N. Kochetkov, L. A. Alexandrova
Publikováno v:
Molecular Biology. 55:143-153
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6076586e53eda844ed7b86a1bcb25fd9
https://doi.org/10.1134/s002689332101012x
https://doi.org/10.1134/s002689332101012x
Autor:
Anastasia L. Khandazhinskaya, Liudmila A. Alexandrova, Elena S. Matyugina, Pavel N. Solyev, Olga V. Efremenkova, Karen W. Buckheit, Maggie Wilkinson, Robert W. Buckheit, Larisa N. Chernousova, Tatiana G. Smirnova, Sofya N. Andreevskaya, Olga G. Leonova, Vladimir I. Popenko, Sergey N. Kochetkov, Katherine L. Seley-Radtke
Publikováno v:
Molecules, Vol 23, Iss 12, p 3069 (2018)
A series of novel 5′-norcarbocyclic derivatives of 5-alkoxymethyl or 5-alkyltriazolyl-methyl uracil were synthesized and the activity of the compounds evaluated against both Gram-positive and Gram-negative bacteria. The growth of Mycobacterium smeg
Externí odkaz:
https://doaj.org/article/df8f90d82864430ebc867f93b84c24a6
Autor:
Anna A. Klimenko, Elena S. Matyugina, Evgeniya B. Logashenko, Pavel N. Solyev, Marina A. Zenkova, Sergey N. Kochetkov, Anastasia L. Khandazhinskaya
Publikováno v:
Molecules, Vol 23, Iss 10, p 2654 (2018)
Here we report the synthesis and biological activity of new 5′-norcarbocyclic derivatives of bicyclic pyrrolo- and furano[2,3-d]pyrimidines with different substituents in the heterocyclic ring. Lead compound 3i, containing 6-pentylphenyl substituen
Externí odkaz:
https://doaj.org/article/bd62b854daba4f88b774317fef51845e
Autor:
S D, Negrya, M V, Jasko, D A, Makarov, P N, Solyev, I L, Karpenko, O V, Shevchenko, O V, Chekhov, A A, Glukhova, B F, Vasilyeva, T A, Efimenko, I G, Sumarukova, O V, Efremenkova, S N, Kochetkov, L A, Alexandrova
Publikováno v:
Molekuliarnaia biologiia. 55(1)
Resistance developed to the majority of drugs used to treat infectious diseases warrants the design of new compounds effective against drug-resistant strains of pathogens. Recently, several groups of modified nucleosides have been synthesized and sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::463180e993b340c1ee950b3c598a50a0
https://pubmed.ncbi.nlm.nih.gov/33566035
https://pubmed.ncbi.nlm.nih.gov/33566035