Zobrazeno 1 - 10
of 48
pro vyhledávání: '"P. N. Shevtsov"'
Autor:
N. A. Lozinskaya, A. A. Morozov, D. R. Bazanov, E. R. Milaeva, D. A. Areshidze, P. N. Shevtsov, L. N. Petrova, E. F. Shevtsova
Publikováno v:
Безопасность и риск фармакотерапии, Vol 11, Iss 2, Pp 165-175 (2023)
Most of the medicinal products that are currently approved and used in clinical practice for neurodegenerative diseases, in particular Alzheimer’s disease, have a compensatory mechanism of action that enhances neurotransmitter signalling. It is an
Externí odkaz:
https://doaj.org/article/46eb329755eb4631add02a51b7a99525
Autor:
Alexander V. Cherpakov,, Vladimir A. Akopyan, Arkady N. Solovyev, Evgeny V. Rozhkov, Sergey N. Shevtsov
Publikováno v:
Вестник Донского государственного технического университета, Vol 11, Iss 3, Pp 312-318 (2018)
The results of finite-element analysis and experimental investigations of the cantilever elastic notched bar flexural modes are presented. The application of the kinking coordinate and tangent angle on the eigenform graphs under the transition throug
Externí odkaz:
https://doaj.org/article/831eb4a7da53423ca2bb38dba8c8152b
Publikováno v:
Obrazovanie i Nauka, Vol 20, Iss 6, Pp 158-182 (2018)
Introduction.The conclusion of the “effective contract” with teachers has recently become one of the innovations at the higher school. According to the drafters of this document, it has to take the position of the economic instrument for increasi
Externí odkaz:
https://doaj.org/article/2f0f337d7396462ca0a8d20e491bdadb
Autor:
N. A. Zefirov, P. D. Korotkova, E. F. Shevtsova, P. N. Shevtsov, A. V. Mamaeva, E. R. Milaeva, O. N. Zefirova
Publikováno v:
Russian Chemical Bulletin. 71:2519-2524
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da1276b7303067d950865afd148fbf22
https://doi.org/10.1007/s11172-022-3682-0
https://doi.org/10.1007/s11172-022-3682-0
Autor:
Еlena V. Rudakova, P. N. Shevtsov, V. B. Sokolov, Alexey Yu. Aksinenko, Elena F. Shevtsova, N. P. Boltneva, Galina F. Makhaeva, T. P. Serkova, Eugene V. Radchenko, Elena A. Pushkareva, Sofya V. Lushchekina, Sergey O. Bachurin, Vladimir A. Palyulin, Rudy J. Richardson, L. G. Dubova, Nadezhda V. Kovaleva
Publikováno v:
Pure and Applied Chemistry. 92:1057-1080
A new series of homobivalent Dimebon analogs, bis-γ-carbolines with alkylene, phenylenedialkylene, and triazole-containing spacers, was synthesized. Doubling the γ-carboline pharmacophore increased inhibitory potency against acetylcholinesterase (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2be2613472bf7c27d470a33b7674fb47
https://doi.org/10.1515/pac-2019-1206
https://doi.org/10.1515/pac-2019-1206
Autor:
Elena F. Shevtsova, Sergei A. Kuznetsov, Olga N. Zefirova, E. A. Lavrushkina, P. N. Shevtsov, N. A. Zefirov, V. M. Shibilev
Publikováno v:
Russian Chemical Bulletin. 69:558-562
Ester of the tubulin ligand, 2-methoxyestradiol, with two molecules of DNA alkylating agent chlorambucil was proposed as a “triple” mutual prodrug for blocking rapid metabolism of the initial steroid. The target conjugate was synthesized via the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b78cfb84f9513ab28d2c23451fb83b61
https://doi.org/10.1007/s11172-020-2798-3
https://doi.org/10.1007/s11172-020-2798-3
Autor:
V. Yu. Dolmatov, A. V. Drobkova, A. G. Lyutov, O. V. Mal’tseva, A. N. Shevtsov, D. V. Borovskoy, G. D. Yelagin, M. V. Karpova, O. A. Vershinina, E. A. Blinova, S. L. Sharygin
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 2(96), Pp 39-42 (2008)
For the first time specific Ig was obtained from blood plasma of donors immunized by combined anthrax vaccine. This Ig conforms to quality standards for intravenous immunoglobulins and includes antibodies to Bacillus anthracis protective antigen in t
Externí odkaz:
https://doaj.org/article/d7cd6131a850409295b2048a92fcb2f9
Autor:
G. F. Makhaeva, E. F. Shevtsova, N. P. Boltneva, N. V. Kovaleva, E. V. Rudakova, L. G. Dubova, P. N. Shevtsov, S. O. Bachurin
Publikováno v:
Доклады Академии наук. 484:104-108
This study presents the synthesis of binary tetrohydro-γ-carbolines with ditriazol spacers of varying length, which exhibit anticholinesterase and antioxidant activity, as compared to the original Dimebon prototype. Anticholinesterase activity sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c1c63bf9cb3827ecd3d44357a115ba8
https://doi.org/10.31857/s0869-56524841104-108
https://doi.org/10.31857/s0869-56524841104-108
Autor:
Elena F. Shevtsova, L. G. Dubova, Sergey O. Bachurin, Elena V. Rudakova, Nadezhda V. Kovaleva, N. P. Boltneva, P. N. Shevtsov, Galina F. Makhaeva
Publikováno v:
Doklady Biochemistry and Biophysics. 484:1-5
The synthesized new binary conjugates of tetrahydro-γ-carbolines, which contained ditriazole spacers of different length, exhibited considerable anticholinesterase and antioxidant activity as well as the potential ability to block the acetylcholines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af947f7886b4cf54bc1b2bbe0fe54b6
https://doi.org/10.1134/s1607672919010010
https://doi.org/10.1134/s1607672919010010
Publikováno v:
Записки Горного института, Vol 224, Pp 178-178 (2017)
The paper describes theory, method and first experimental results of research on the interaction between electromagnetic waves of extremely low and ultra low frequency (0.1-200 Hz), the Earth crust and ionosphere in the field of two mutually orthogon
Externí odkaz:
https://doaj.org/article/1b68dfd426e645a9b20c9228d33f9907