Výsledky vyhledávání - "P. N. M. Tijburg"

Activation of the coagulation mechanism on tumor necrosis factor-stimulated cultured endothelial cells and their extracellular matrix. The role of flow and factor IX/IXa

Autor: P. N. M. Tijburg, B. Wollitzky, A. Rimon, D. Handley, P. G. De Groot, J Ryan, P. P. Nawroth, S. Rimon, David M. Stern, J. J. Sixma

Publikováno v: Journal of Biological Chemistry. 266:12067-12074

Infusion of tumor necrosis factor (TNF) into tumor-bearing mice led to intravascular clot formation with fibrin deposition in microvessels in the tumor bed in close association with the vessel wall, which could be prevented by active site-blocked fac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eadf44ac46f4473738cb36eb9054f8fb
https://doi.org/10.1016/s0021-9258(18)99066-6

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Quantification of fibrin deposition in flowing blood with peroxidase-labeled fibrinogen. High shear rates induce decreased fibrin deposition and appearance of fibrin monomers

Autor: J. J. Sixma, P. N. M. Tijburg, P. G. De Groot, M. J. W. Ijsseldijk

Publikováno v: Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 11:211-220

To study fibrin incorporation into thrombi at different wall shear rates, a new method to study fibrin deposition on extracellular matrixes underlying stimulated endothelial cells under flow conditions was developed. For this method, we used fibrinog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ab4a96bab72413ff636bcd6f7d658d
https://doi.org/10.1161/01.atv.11.2.211

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Formation of meizothrombin as intermediate in factor Xa-catalyzed prothrombin activation on endothelial cells. The influence of thrombin on the reaction mechanism

Autor: W.L. van Heerde, M. Hessing, P. N. M. Tijburg, H. M. Leenhouts, P. G. De Groot, B. N. Bouma

Publikováno v: Journal of Biological Chemistry. 266:4017-4022

Incubation of prothrombin on cultured human umbilical vein endothelial cells with factor Xa and calcium ions induced the activation of prothrombin. The mechanism of prothrombin activation was analyzed on sodium dodecyl sulfate gels using immuno- and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::146baf6e6e2f23bcc03f9fda569c052d
https://doi.org/10.1016/s0021-9258(19)67895-6

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Platelet adhesion to extracellular matrices of cultured cells

Autor: P. N. M. Tijburg, Patricia N. E. M. Nievelstein, A. Pronk, Philip G. de Groot, J J Zwaginga, G Hindriks, J. D. Banga, Jan J. Sixma

Publikováno v: Annals of the New York Academy of Sciences. 614

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586344400cf36a248ecb380f31b6dec9
https://pubmed.ncbi.nlm.nih.gov/2024883

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Endothelium in Hemostasis and Thrombosis

Autor: Philip G. de Groot, P. N. M. Tijburg, Jaap Jan Zwaginga, Hetty C. de Boer

Publikováno v: Vascular Dynamics ISBN: 9781468478587

In the normal vasculature, blood platelets circulate freely through the vessels and no fibrin is formed. The capacity of the endothelium, which forms the inner lining of the blood vessel wall, to inhibit the activation of the coagulation cascade and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c246920920f544cb50cf8bc5f42de49f
https://doi.org/10.1007/978-1-4684-7856-3_12

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