Zobrazeno 1 - 10
of 19
pro vyhledávání: '"P. N. Foley"'
Autor:
Robert F. Hillary, Danni A. Gadd, Zhana Kuncheva, Tasos Mangelis, Tinchi Lin, Kyle Ferber, Helen McLaughlin, Heiko Runz, Biogen Biobank Team, Riccardo E. Marioni, Christopher N. Foley, Benjamin B. Sun
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Understanding how gene-environment interactions (GEIs) influence the circulating proteome could aid in biomarker discovery and validation. The presence of GEIs can be inferred from single nucleotide polymorphisms that associate with phenotyp
Externí odkaz:
https://doaj.org/article/b3af4159742445ef8cc58e96088e9052
Autor:
H. A. Dugan, P. T. Doran, D. Grombacher, E. Auken, T. Bording, N. Foged, N. Foley, J. Mikucki, R. A. Virginia, S. Tulaczyk
Publikováno v:
The Cryosphere, Vol 16, Pp 4977-4983 (2022)
Since the 1960s, a deep groundwater system in Wright Valley, Antarctica, has been the hypothesized source of brines to hypersaline Don Juan Pond and Lake Vanda, both of which are rich in calcium and chloride. Modeling studies do not support other pos
Externí odkaz:
https://doaj.org/article/c2614cb54e364c31b9d9fd93ecec0022
Autor:
Benjamin B. Sun, Stephanie J. Loomis, Fabrizio Pizzagalli, Natalia Shatokhina, Jodie N. Painter, Christopher N. Foley, Biogen Biobank Team, Megan E. Jensen, Donald G. McLaren, Sai Spandana Chintapalli, Alyssa H. Zhu, Daniel Dixon, Tasfiya Islam, Iyad Ba Gari, Heiko Runz, Sarah E. Medland, Paul M. Thompson, Neda Jahanshad, Christopher D. Whelan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Genetic associations with particular patterns of brain folding may provide insight into brain development and function. Here, the authors identify and replicate 388 genetic associations with brain sulcal morphology across 40,169 UK Biobank MRI scans,
Externí odkaz:
https://doaj.org/article/6a31732e43d94e97bac89d4842fe34f4
Autor:
Christopher N. Foley, James R. Staley, Philip G. Breen, Benjamin B. Sun, Paul D. W. Kirk, Stephen Burgess, Joanna M. M. Howson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Statistical colocalisation is a method to identify causal genes and shared genetic aetiology across traits. Here, the authors describe HyPrColoc, an efficient Bayesian divisive clustering algorithm which integrates summary statistics from genome-wide
Externí odkaz:
https://doaj.org/article/3c6045c88c554f35b4d4238ae36ad69a
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Mendelian randomization (MR) is a method for inferring causal relationships between risk factors and outcomes via associated genetic variants. Here, Burgess et al. develop the contamination mixture method which yields robust MR results in the presenc
Externí odkaz:
https://doaj.org/article/74ff71ea549c46d682697de209ffda29
Autor:
Jim R. Broadbent, Christopher N. Foley, Andrew J. Grant, Amy M. Mason, James R. Staley, Stephen Burgess
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
The MendelianRandomization package is a software package written for the R software environment that implements methods for Mendelian randomization based on summarized data. In this manuscript, we describe functions that have been added to the packag
Externí odkaz:
https://doaj.org/article/4b0e8a351cbb448585cebfcebcfb602d
Publikováno v:
Frontiers in Big Data, Vol 3 (2020)
Little attention has been paid to the measurement of risk to privacy in Database Management Systems, despite their prevalence as a modality of data access. This paper proposes PriDe, a quantitative privacy metric that provides a measure (privacy scor
Externí odkaz:
https://doaj.org/article/96ae65dedcbe4cab9ebc4d1516d60425
Publikováno v:
Kidney International Reports, Vol 3, Iss 1, Pp 148-154 (2018)
Although the management of scleroderma continues to evolve, it is unknown whether the burden of end-stage kidney disease (ESKD) treated with maintenance renal replacement therapy from SD has changed. Methods: We examined United States Renal Data Syst
Externí odkaz:
https://doaj.org/article/05a21979c6fa4d12a15fca47fea6e3f4
Publikováno v:
Neurología, Vol 27, Iss 4, Pp 234-244 (2012)
Resumen: Introducción: El hombro doloroso hemipléjico es frecuente después de un ictus. Su aparición conlleva además del dolor, una limitación para las actividades de la vida diaria, así como para la participación en programas específicos de
Externí odkaz:
https://doaj.org/article/9095183fb648449384c4fb76bbab1b58
Publikováno v:
Neurología (English Edition), Vol 27, Iss 4, Pp 234-244 (2012)
Introduction: The hemiplegic shoulder pain is common after a stroke. Its appearance brings pain and limits daily living activities as well as participation in specific Neuro-rehabilitation programs. All this leads to a worse functional outcome. Good
Externí odkaz:
https://doaj.org/article/882195dddc87497f991e37cdee458ac9