Prior metabolic surgery reduced COVID-19 severity: Systematic analysis from year one of the COVID-19 pandemic

Autor: G. Craig Wood, Peter N. Benotti, Rodrigo M. Fano, James T. Dove, David DK. Rolston, Anthony T. Petrick, Christopher D. Still

Publikováno v: Heliyon, Vol 9, Iss 5, Pp e15824- (2023)

Background: Obesity is a risk factor for COVID-19 severity. Recent studies suggest that prior metabolic surgery (MS) modifies the risk of COVID-19 severity. Methods: COVID-19 outcomes were compared between patients with MS (n = 287) and a matched coh

Externí odkaz: https://doaj.org/article/966248ef94d54dfdbe9bb273d9762132

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

Autor: Viktoria Gusarova, Colm O’Dushlaine, Tanya M. Teslovich, Peter N. Benotti, Tooraj Mirshahi, Omri Gottesman, Cristopher V. Van Hout, Michael F. Murray, Anubha Mahajan, Jonas B. Nielsen, Lars Fritsche, Anders Berg Wulff, Daniel F. Gudbjartsson, Marketa Sjögren, Connor A. Emdin, Robert A. Scott, Wen-Jane Lee, Aeron Small, Lydia C. Kwee, Om Prakash Dwivedi, Rashmi B. Prasad, Shannon Bruse, Alexander E. Lopez, John Penn, Anthony Marcketta, Joseph B. Leader, Christopher D. Still, H. Lester Kirchner, Uyenlinh L. Mirshahi, Amr H. Wardeh, Cassandra M. Hartle, Lukas Habegger, Samantha N. Fetterolf, Teresa Tusie-Luna, Andrew P. Morris, Hilma Holm, Valgerdur Steinthorsdottir, Patrick Sulem, Unnur Thorsteinsdottir, Jerome I. Rotter, Lee-Ming Chuang, Scott Damrauer, David Birtwell, Chad M. Brummett, Amit V. Khera, Pradeep Natarajan, Marju Orho-Melander, Jason Flannick, Luca A. Lotta, Cristen J. Willer, Oddgeir L. Holmen, Marylyn D. Ritchie, David H. Ledbetter, Andrew J. Murphy, Ingrid B. Borecki, Jeffrey G. Reid, John D. Overton, Ola Hansson, Leif Groop, Svati H. Shah, William E. Kraus, Daniel J. Rader, Yii-Der I. Chen, Kristian Hveem, Nicholas J. Wareham, Sekar Kathiresan, Olle Melander, Kari Stefansson, Børge G. Nordestgaard, Anne Tybjærg-Hansen, Goncalo R. Abecasis, David Altshuler, Jose C. Florez, Michael Boehnke, Mark I. McCarthy, George D. Yancopoulos, David J. Carey, Alan R. Shuldiner, Aris Baras, Frederick E. Dewey, Jesper Gromada

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)

Genetic variation in ANGPTL4 is associated with lipid traits. Here, the authors find that predicted loss-of-function variants in ANGPTL4 are associated with glucose homeostasis and reduced risk of type 2 diabetes and that Angptl4 −/− mice on a hi

Externí odkaz: https://doaj.org/article/a3d832a109514250b3a42f9eaa1a1b95

Portal mesenteric shunting for reconstruction of the visceral venous system

Autor: H, Dardik, A, Shander, S, Dardik, F, Silvestri, A, Ciervo, P N, Benotti

Publikováno v: Journal of the American College of Surgeons. 191(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a86a6a569183d018575e79c8f1e10ace
https://pubmed.ncbi.nlm.nih.gov/11030255

Nutritional support of the mechanically ventilated patient

Autor: S A, Shikora, P N, Benotti

Publikováno v: Respiratory care clinics of North America. 3(1)

As with all critically ill patients, those requiring mechanical ventilation are susceptible to the wasting of illness and cannot survive without prompt nutritional support. It may be fair to say that the proper provision of nutrients, and in particul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::12c412894079868b3d3b34b98c093185
https://pubmed.ncbi.nlm.nih.gov/9390903

Surgical intensive care unit resource use in a specialty referral hospital: I. Predictors of early death and cost implications

Autor: B C, Borlase, J T, Baxter, P N, Benotti, M, Stone, E, Wood, R A, Forse, G L, Blackburn, G, Steele

Publikováno v: Surgery. 109(6)

The rationing of medical care prioritizes the need for early predictors of death in the surgical intensive care unit (SICU). We prospectively studied 100 consecutive SICU admissions, looking for predictors of early death in the SICU and the cost impl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::68e21c959451e211a0f8cda7aa00a10a
https://pubmed.ncbi.nlm.nih.gov/2042086