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Akademický článek

Predicting future adoption of early-stage innovations for smart farming: A case study investigating critical factors influencing use of smart feeder technology for potential delivery of methane inhibitors in pasture-grazed dairy systems

Autor: Benjamin Marmont, Callum Eastwood, Elena Minnee, Zack Dorner, Mark Neal, David Silva-Villacorta

Publikováno v: Smart Agricultural Technology, Vol 9, Iss , Pp 100549- (2024)

Globally, livestock farmers are challenged with reducing greenhouse gas emissions to mitigate climate change. A potential option for pasture-based dairy farmers involves including methane-inhibiting compounds in the diet. A novel approach to deliver

Externí odkaz: https://doaj.org/article/22fa4aaeace54a56b18a5228521c815d

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Akademický článek

Label-free detection of prostaglandin transporter (SLCO2A1) function and inhibition: insights by wound healing and TRACT assays

Autor: Tamara A. M. Mocking, Wieke M. van Oostveen, Jacobus P. D. van Veldhoven, Hugo Minnee, Cynthia M. Fehres, Charles E. Whitehurst, Adriaan P. IJzerman, Laura H. Heitman

Publikováno v: Frontiers in Pharmacology, Vol 15 (2024)

The prostaglandin transporter (PGT, SLCO2A1) mediates transport of prostanoids (a.o. prostaglandin E2 (PGE2)) into cells and thereby promotes their degradation. Overexpression of PGT leads to low extracellular PGE2 levels and has been linked to impai

Externí odkaz: https://doaj.org/article/e0cc08e3ad25430fb31c87cdf54e7ca2

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Akademický článek

Pre-transplant kidney quality evaluation using photoacoustic imaging during normothermic machine perfusion

Autor: Anton V. Nikolaev, Yitian Fang, Jeroen Essers, Kranthi M. Panth, Gisela Ambagtsheer, Marian C. Clahsen-van Groningen, Robert C. Minnee, Gijs van Soest, Ron W.F. de Bruin

Publikováno v: Photoacoustics, Vol 36, Iss , Pp 100596- (2024)

Due to the shortage of kidneys donated for transplantation, surgeons are forced to use the organs with an elevated risk of poor function or even failure. Although the existing methods for pre-transplant quality evaluation have been validated over dec

Externí odkaz: https://doaj.org/article/0cf1e3a50ff846fbab4247e783734fab

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Akademický článek

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Akademický článek

Portable System for In-Clinic Differentiation of Skin Cancers from Benign Skin Lesions and Inflammatory Dermatoses

Autor: Michel Nieuwoudt, Paul Jarrett, Hannah Matthews, Michelle Locke, Marco Bonesi, Brydon Burnett, Hannah Holtkamp, Claude Aguergaray, Ira Mautner, Thom Minnee, M. Cather Simpson

Publikováno v: JID Innovations, Vol 4, Iss 1, Pp 100238- (2024)

The exquisite sensitivity of Raman spectroscopy for detecting biomolecular changes in skin cancer has previously been explored; however, this mostly required analysis of excised tissue samples using bulky, immobile laboratory instrumentation. In this

Externí odkaz: https://doaj.org/article/2556c5ee0d374476bc90a72d0b852db6

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Akademický článek

Do treats facilitate the interpretation of findings on caloric restriction?

Autor: Jan N M IJzermans, Robert A Pol, Christiaan Albert Johan Oudmaijer, Robert C Minnee, Wilbert Vermeij

Publikováno v: BMJ Nutrition, Prevention & Health, Vol 6, Iss 2 (2023)

Introduction Food can build social bonds and enhance interpersonal relationships. An area of research perhaps at odds with food abundance, is caloric restriction (CR), intermittent fasting (IF) or short-term fasting (STF). We aimed to study the impac

Externí odkaz: https://doaj.org/article/97550cf34cf042d7a56a5aab1cca3303

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Akademický článek

Virus-specific TRM cells of both donor and recipient origin reside in human kidney transplants

Autor: Daphne M. Hullegie-Peelen, Hector Tejeda Mora, Dennis A. Hesselink, Eric M.J. Bindels, Thierry P.P. van den Bosch, Marian C. Clahsen-van Groningen, Marjolein Dieterich, Sebastiaan Heidt, Robert C. Minnee, Georges M.G.M. Verjans, Martin J. Hoogduijn, Carla C. Baan

Publikováno v: JCI Insight, Vol 8, Iss 21 (2023)

Tissue-resident lymphocytes (TRLs) are critical for local protection against viral pathogens in peripheral tissue. However, it is unclear if TRLs perform a similar role in transplanted organs under chronic immunosuppressed conditions. In this study,

Externí odkaz: https://doaj.org/article/fb29d72fe9e1487c9936e377474c2faa

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Akademický článek

Impact of Extraction Time During Donation After Circulatory Death Organ Procurement on Kidney Function After Transplantation in The Netherlands

Autor: Erika van Straalen, MSc, Elsaline Rijkse, MD, PhD, AnneLoes van Staa, MD, PhD, Paul M. Rebers, Hanneke J.A.M. Hagenaars, Jacqueline van de Wetering, MD, PhD, Jan N.M. Ijzermans, MD, PhD, Robert C. Minnee, MD, PhD

Publikováno v: Transplantation Direct, Vol 9, Iss 11, p e1538 (2023)

Background. In The Netherlands, 60% of deceased-donor kidney offers are after donation after circulatory death. Cold and warm ischemia times are known risk factors for delayed graft function (DGF) and inferior allograft survival. Extraction time is a

Externí odkaz: https://doaj.org/article/2b6d2318ce2046b1a440d56620689faf

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