Zobrazeno 1 - 10
of 1 363
pro vyhledávání: '"P. Medema"'
Autor:
Maarten de Jong, Maarten F. Schim van der Loeff, Rémy Schilperoort, Harry Vennema, Charlie van der Weijden, Jeroen Langeveld, Matthijs Welkers, Maria Prins, Ana Maria de Roda Husman, Ewout Fanoy, Gertjan Medema
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Enteric hepatitis A virus (HAV) infections during childhood are often asymptomatic but may cause severe illness in adults. To improve public health surveillance we assessed the applicability of sewage monitoring during an HAV outb
Externí odkaz:
https://doaj.org/article/4a692118f6e14c469a4b283cf979be99
Autor:
Barbara R. Terlouw, Friederike Biermann, Sophie P. J. M. Vromans, Elham Zamani, Eric J. N. Helfrich, Marnix H. Medema
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Natural products are molecules that fulfil a range of important ecological functions. Many natural products have been exploited for pharmaceutical and agricultural applications. In contrast to many other specialised metabolites, the products
Externí odkaz:
https://doaj.org/article/05b9a26e73d14f05a536e4c5488a18c0
Publikováno v:
Organoids, Vol 3, Iss 3, Pp 194-202 (2024)
Colorectal cancer (CRC) is the third most common cancer worldwide and it is the second leading cause of cancer death. In CRC, as in most cancers, the formation of metastasis through the migration and invasion of cancer cells to distant organs is asso
Externí odkaz:
https://doaj.org/article/0e19b87ac7274bf8992237ad5c6f804d
Autor:
Wanrong Luo, Min Zhao, Mohammed Dwidar, Yang Gao, Liyuan Xiang, Xueting Wu, Marnix H. Medema, Shu Xu, Xiaozhi Li, Hendrik Schäfer, Minhu Chen, Rui Feng, Yijun Zhu
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-20 (2024)
Abstract Background H2S imbalances in the intestinal tract trigger Crohn's disease (CD), a chronic inflammatory gastrointestinal disorder characterized by microbiota dysbiosis and barrier dysfunction. However, a comprehensive understanding of H2S gen
Externí odkaz:
https://doaj.org/article/42fb619f1b20450f946768897438587a
Autor:
Xabier Vergara, Anna G. Manjón, Marcel de Haas, Ben Morris, Ruben Schep, Christ Leemans, Anoek Friskes, Roderick L. Beijersbergen, Mathijs A. Sanders, René H. Medema, Bas van Steensel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract DNA double-strand breaks are repaired by multiple pathways, including non-homologous end-joining (NHEJ) and microhomology-mediated end-joining (MMEJ). The balance of these pathways is dependent on the local chromatin context, but the underly
Externí odkaz:
https://doaj.org/article/6009cbab086a43759a3f31b9c33c7f5d
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-8 (2024)
Abstract Effective visualization of small molecules is paramount in conveying concepts and results in cheminformatics. Scalable vector graphics (SVG) are preferred for creating such visualizations, as SVGs can be easily altered in post-production and
Externí odkaz:
https://doaj.org/article/49db27d1f1e54435bef280295e73d468
Autor:
Amber P. van der Zalm, Mark P. G. Dings, Paul Manoukian, Hannah Boersma, Reimer Janssen, Peter Bailey, Jan Koster, Danny Zwijnenburg, Richard Volckmann, Sanne Bootsma, Cynthia Waasdorp, Monique van Mourik, Dionne Blangé, Tom van den Ende, César I. Oyarce, Sarah Derks, Aafke Creemers, Eva A. Ebbing, Gerrit K. Hooijer, Sybren L. Meijer, Mark I. van Berge Henegouwen, Jan Paul Medema, Hanneke W. M. van Laarhoven, Maarten F. Bijlsma
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background Despite the advent of neoadjuvant chemoradiotherapy (CRT), overall survival rates of esophageal adenocarcinoma (EAC) remain low. A readily induced mesenchymal transition of EAC cells contributes to resistance to CRT. Methods In th
Externí odkaz:
https://doaj.org/article/d7fc9df802d34addb7ab614129c458e9
Publikováno v:
Physica C, 583 (2021): 1353849
Intermodulation distortion (IMD) of microwave signals incident upon a superconducting YBa2Cu3O7 thin film sample on a LaAlO3 substrate is shown to relax as the sample magnetization also relaxes, revealing the signature of fluxon decay in the microwav
Externí odkaz:
http://arxiv.org/abs/2208.13248
Autor:
Philippe Quevauviller, Klaus Hinsby, Ida Karlsson Seidenfaden, David Pulido Velázquez, Manuel Sapiano, Rosario Coelho, Peter Gattinesi, Philipp Hohenblum, Vaclav Jirovsky, Fatima Marinheiro, Luis Simas, Rui Teixeira, Rita Ugarelli, Monica Cardarilli, Sotirios Paraskevopoulos, Stelios Vrachimis, Gertjan Medema, Demetrios Eliades, Francesco La Vigna
Publikováno v:
Acque Sotterranee, Vol 13, Iss 3 (2024)
“Water security” and “water safety” is defined differently. As the terms are related they may lead to confusion and misinterpretations, depending on the context. Water security generally refers to a lack of resources of an acceptable quality,
Externí odkaz:
https://doaj.org/article/4cb8bdc0a0974ef68e74314593e65cfe
Autor:
Floriane Odje, David Meijer, Elena von Coburg, Justin J. J. van der Hooft, Sebastian Dunst, Marnix H. Medema, Andrea Volkamer
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
The cell painting (CP) assay has emerged as a potent imaging-based high-throughput phenotypic profiling (HTPP) tool that provides comprehensive input data for in silico prediction of compound activities and potential hazards in drug discovery and tox
Externí odkaz:
https://doaj.org/article/db08b0896cf645dfbf1580b3e2b0f380