Zobrazeno 1 - 10
of 975
pro vyhledávání: '"P. Mauvais"'
Autor:
Dragana Lovre, M. M. Fahd Qadir, Kristin Bateman, Leia Y Saltzman, Mya Sherman, Franck Mauvais-Jarvis
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract COVID-19 outcomes are less severe in women than men suggesting that female sex is protective. The steroids estradiol (E2) and progesterone (P4) promote anti-inflammatory immune responses and their therapeutic use for COVID-19 has been under
Externí odkaz:
https://doaj.org/article/70ee37c323454810b8a766ddd12fa085
Autor:
Anil Sakamuri, Bruna Visniauskas, Isabella Kilanowski-Doroh, Alexandra B. McNally, Ariane Imulinde, Anne Kamau, Divya Sengottaian, John McLachlan, Montserrat Anguera, Franck Mauvais-Jarvis, Sarah H. Lindsey, Benard O. Ogola
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Sex hormones and sex chromosomes play a vital role in cardiovascular disease. Testosterone plays a crucial role in men’s health. Lower testosterone level is associated with cardiovascular and cardiometabolic diseases, including
Externí odkaz:
https://doaj.org/article/56b41c68258848e4b79ab5b51294a26b
Autor:
Shuaishuai Zhu, Emmanuelle Waeckel-Énée, Masaya Oshima, Anna Moser, Marie-Andrée Bessard, Abdelaziz Gdoura, Kevin Roger, Nina Mode, Joanna Lipecka, Ayse Yilmaz, Barbara Bertocci, Julien Diana, Benjamin Saintpierre, Ida Chiara Guerrera, Raphael Scharfmann, Stefania Francesconi, François-Xavier Mauvais, Peter van Endert
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109929- (2024)
Summary: Tuning of protein homeostasis through mobilization of the unfolded protein response (UPR) is key to the capacity of pancreatic beta cells to cope with variable demand for insulin. Here, we asked how insulin-degrading enzyme (IDE) affects bet
Externí odkaz:
https://doaj.org/article/ef74b2002b644e86886ed16b4a9bb5e4
Autor:
Mona Elgazzaz, Clara Berdasco, Jone Garai, Melody Baddoo, Shiping Lu, Hisham Daoud, Jovanny Zabaleta, Franck Mauvais-Jarvis, Eric Lazartigues
Publikováno v:
Molecular Metabolism, Vol 80, Iss , Pp 101864- (2024)
Objective: Maternal exposure during pregnancy is a strong determinant of offspring health outcomes. Such exposure induces changes in the offspring epigenome resulting in gene expression and functional changes. In this study, we investigated the effec
Externí odkaz:
https://doaj.org/article/6489b879ed3342e9a6f9cdf90331e953
Autor:
Yilin Yoshida, Zhipeng Chen, Robin L. Baudier, Marie Krousel‐Wood, Amanda H. Anderson, Vivian A. Fonseca, Franck Mauvais‐Jarvis
Publikováno v:
Journal of Diabetes, Vol 15, Iss 2, Pp 185-189 (2023)
Highlights Fasting glucose‐defined prediabetes and undiagnosed diabetes based on the American Diabetes Association criteria were associated with a greater risk of coronary heart disease, stroke, and composite atherosclerotic cardiovascular disease
Externí odkaz:
https://doaj.org/article/0a25cead3b3645bea18475d6811f8901
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection produces more severe symptoms and a higher mortality in men than in women. The role of biological sex in the immune response to SARS-CoV-2 is believed to exp
Externí odkaz:
https://doaj.org/article/8692671d9a754baaa62dd0c030482bb4
Autor:
Yilin Yoshida, San Chu, Sarah Fox, Yuanhao Zu, Dragana Lovre, Joshua L. Denson, Lucio Miele, Franck Mauvais-Jarvis
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Objective The impact of comorbidities and biomarkers on COVID-19 severity vary by sex but have not yet been verified in population-based studies. We examined the association of comorbidities, inflammatory biomarkers, and severe outcomes in m
Externí odkaz:
https://doaj.org/article/6a3d3e1304d04383a793c2757657e862
Autor:
Joséphine Magnin, Isabelle Fournel, Alexandre Doussot, Jean-Marc Régimbeau, Philippe Zerbib, Guillaume Piessen, Laura Beyer-Berjot, Sophie Deguelte, Zaher Lakkis, Lilian Schwarz, David Orry, Ahmet Ayav, Fabrice Muscari, François Mauvais, Guillaume Passot, Nelson Trelles, Aurélien Venara, Stéphane Benoist, Mathieu Messager, David Fuks, Baptiste Borraccino, Christophe Trésallet, Alain Valverde, François-Régis Souche, Astrid Herrero, Sébastien Gaujoux, Jérémie Lefevre, Abderrahmane Bourredjem, Amélie Cransac, Pablo Ortega-Deballon
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background The modulation of perioperative inflammation seems crucial to improve postoperative morbidity and cancer-related outcomes in patients undergoing oncological surgery. Data from the literature suggest that perioperative corticostero
Externí odkaz:
https://doaj.org/article/614c3b21890146d489d2dcceb3cec156
Autor:
Weiwei Xu, M.M. Fahd Qadir, Daniela Nasteska, Paula Mota de Sa, Caroline M. Gorvin, Manuel Blandino-Rosano, Charles R. Evans, Thuong Ho, Evgeniy Potapenko, Rajakrishnan Veluthakal, Fiona B. Ashford, Stavroula Bitsi, Jia Fan, Manika Bhondeley, Kejing Song, Venkata N. Sure, Siva S.V.P. Sakamuri, Lina Schiffer, Wandy Beatty, Rachael Wyatt, Daniel E. Frigo, Xiaowen Liu, Prasad V. Katakam, Wiebke Arlt, Jochen Buck, Lonny R. Levin, Tony Hu, Jay Kolls, Charles F. Burant, Alejandra Tomas, Matthew J. Merrins, Debbie C. Thurmond, Ernesto Bernal-Mizrachi, David J. Hodson, Franck Mauvais-Jarvis
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112529- (2023)
Summary: Male mice lacking the androgen receptor (AR) in pancreatic β cells exhibit blunted glucose-stimulated insulin secretion (GSIS), leading to hyperglycemia. Testosterone activates an extranuclear AR in β cells to amplify glucagon-like peptide
Externí odkaz:
https://doaj.org/article/557572b83b5a4a7ca84c9f23c0810f39
Autor:
Jean Pinson, Jean-Jacques Tuech, Mehdi Ouaissi, Murielle Mathonnet, François Mauvais, Estelle Houivet, Elie Lacroix, Julie Rondeaux, Charles Sabbagh, Valérie Bridoux
Publikováno v:
BMC Surgery, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background Traditionally, patients with peritonitis Hinchey III and IV due to perforated diverticulitis were treated with Hartmann’s procedure. In the past decade, resection and primary anastomosis have gained popularity over Hartmann’s
Externí odkaz:
https://doaj.org/article/1b7df64a59db45b3bcff2ee70a270f32