Zobrazeno 1 - 10
of 115
pro vyhledávání: '"P. Mannuccio Mannucci"'
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/580265dc8f384ec499e80fc59669f54f
Autor:
Roberto Castelli, Antonio Gidaro, Roberto Manetti, Paolo Castiglia, Alessandro Palmerio Delitala, Pier Mannuccio Mannucci, Samantha Pasca
Publikováno v:
Vaccines, Vol 12, Iss 7, p 709 (2024)
Acquired hemophilia A (AHA) is a rare bleeding disorder (1.4 per million inhabitants per year) caused by neutralizing antibodies against factor VIII. Although uncommon, these autoantibodies can cause a high rate of morbidity and mortality. Several co
Externí odkaz:
https://doaj.org/article/f63743adef744e0288e029e79621673e
Publikováno v:
Haematologica, Vol 109, Iss 5 (2023)
In hemophilia, the unmet needs regarding adherence to prophylaxis and lack of effective long-term prophylaxis regimens, especially in patients with inhibitors, led to the production of emicizumab, the first non-factor medicine for subcutaneous admini
Externí odkaz:
https://doaj.org/article/584490ca70054189a18a693a04bb50de
Publikováno v:
Haematologica, Vol 109, Iss 4 (2023)
D-dimer, a soluble fibrin degradation product that originates from plasmin-induced degradation of cross-linked fibrin, is an important biomarker of coagulation activation and secondary fibrinolysis that is routinely used to rule out venous thromboemb
Externí odkaz:
https://doaj.org/article/514eacf085404729b613a83a28666bed
Autor:
Pier Mannuccio Mannucci, Olivier Jolliet, Erik Meijaard, Joanne Slavin, Mario Rasetti, Alberto Aleta, Yamir Moreno, Carlo Agostoni
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
Sustainable nutrition represents a formidable challenge for providing people with healthy, nutritious and affordable food, while reducing waste and impacts on the environment. Acknowledging the complexity and multi-dimensional nature of the food syst
Externí odkaz:
https://doaj.org/article/e9a35fd99bca44afa483fe9f0f65ee41
Autor:
Chiara Macchi, Cesare R. Sirtori, Alberto Corsini, Pier Mannuccio Mannucci, Massimiliano Ruscica
Publikováno v:
Environment International, Vol 175, Iss , Pp 107923- (2023)
According to the WHO, the entire global population is exposed to air pollution levels higher than recommended for health preservation. Air pollution is a complex mixture of nano- to micro-sized particles and gaseous components that poses a major glob
Externí odkaz:
https://doaj.org/article/0eddda90e709447ebb39575a124fc027
Autor:
Pier Mannuccio Mannucci
Publikováno v:
Bleeding, Thrombosis and Vascular Biology, Vol 2, Iss 1 (2023)
Very few rare diseases have witnessed the gigantic progress in patient care that took place for the hemophilias in the last 20 years. The first landmark was in the 1990s, when recombinant DNA technology afforded the industrial production, regulatory
Externí odkaz:
https://doaj.org/article/f396f7ea1aaa44e0a71ccd63bf1ca6c1
Publikováno v:
Haematologica, Vol 108, Iss 7 (2023)
With the striking advances in hemophilia care that have materialized particularly in the last two decades, an increasing number of persons with hemophilia (PWH) have achieved a quality of life and life expectancy very close to that of unaffected indi
Externí odkaz:
https://doaj.org/article/a492f3894cdb44e58d00e21dd6155687
Autor:
Pier Mannuccio Mannucci
Publikováno v:
Bleeding, Thrombosis and Vascular Biology, Vol 1, Iss 1 (2022)
The phase 3 clinical study of gene transfer in hemophilia A using the BioMarin vector AAV5-hFVIII-SQ (also identified as valoctocogene roxaparvovec) recently reported the results obtained in as many as 134 adult men with severe hemophilia A, so that
Externí odkaz:
https://doaj.org/article/6e7b871d822749f98ebc70508222fde5
Autor:
Pier Mannuccio Mannucci
Publikováno v:
Bleeding, Thrombosis and Vascular Biology, Vol 1, Iss 1 (2022)
This narrative review article summarizes the strong available evidence that casually links indoor and outdoor air pollution to cardiovascular disease. It also discusses as a possible approach to mitigate this ubiquitous risk factor the use in the hou
Externí odkaz:
https://doaj.org/article/755b4cada33b4a2d91c507e1a4c03fd3