Zobrazeno 1 - 10
of 2 803
pro vyhledávání: '"P. Macklin"'
Autor:
R. Laubenbacher, A. Niarakis, T. Helikar, G. An, B. Shapiro, R. S. Malik-Sheriff, T. J. Sego, A. Knapp, P. Macklin, J. A. Glazier
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-5 (2022)
Abstract Digital twins, customized simulation models pioneered in industry, are beginning to be deployed in medicine and healthcare, with some major successes, for instance in cardiovascular diagnostics and in insulin pump control. Personalized compu
Externí odkaz:
https://doaj.org/article/c549c9a9ea144d89bda0c789fa1dfa1d
In this work, we present a GPU-accelerated library for the underlying components of Kolmogorov-Arnold Networks (KANs), along with an algorithm to eliminate bounded grids in KANs. The GPU-accelerated library reduces the computational complexity of Bas
Externí odkaz:
http://arxiv.org/abs/2408.11200
Autor:
Ruscone, Marco, Checcoli, Andrea, Heiland, Randy, Barillot, Emmanuel, Macklin, Paul, Calzone, Laurence, Noël, Vincent
Multiscale models provide a unique tool for studying complex processes that study events occurring at different scales across space and time. In the context of biological systems, such models can simulate mechanisms happening at the intracellular lev
Externí odkaz:
http://arxiv.org/abs/2406.18371
Mechanistic learning, the synergistic combination of knowledge-driven and data-driven modeling, is an emerging field. In particular, in mathematical oncology, the application of mathematical modeling to cancer biology and oncology, the use of mechani
Externí odkaz:
http://arxiv.org/abs/2312.07026
HandyPriors: Physically Consistent Perception of Hand-Object Interactions with Differentiable Priors
Autor:
Zhang, Shutong, Qiao, Yi-Ling, Zhu, Guanglei, Heiden, Eric, Turpin, Dylan, Liu, Jingzhou, Lin, Ming, Macklin, Miles, Garg, Animesh
Various heuristic objectives for modeling hand-object interaction have been proposed in past work. However, due to the lack of a cohesive framework, these objectives often possess a narrow scope of applicability and are limited by their efficiency or
Externí odkaz:
http://arxiv.org/abs/2311.16552
Autor:
Laubenbacher, Reinhard, Adler, Fred, An, Gary, Castiglione, Filippo, Eubank, Stephen, Fonseca, Luis L., Glazier, James, Helikar, Tomas, Jett-Tilton, Marti, Kirschner, Denise, Macklin, Paul, Mehrad, Borna, Moore, Beth, Pasour, Virginia, Shmulevich, Ilya, Smith, Amber, Voigt, Isabel, Yankeelov, Thomas E., Ziemssen, Tjalf
Publikováno v:
npj Syst Biol Appl 10, 19 (2024). PMID: 38365857
Medical digital twins are computational models of human biology relevant to a given medical condition, which can be tailored to an individual patient, thereby predicting the course of disease and individualized treatments, an important goal of person
Externí odkaz:
http://arxiv.org/abs/2310.18374
Autor:
Ross C. Gruber, Gregory S. Wirak, Anna S. Blazier, Lan Lee, Michael R. Dufault, Nellwyn Hagan, Nathalie Chretien, Michael LaMorte, Timothy R. Hammond, Agnes Cheong, Sean K. Ryan, Andrew Macklin, Mindy Zhang, Nilesh Pande, Evis Havari, Timothy J. Turner, Anthony Chomyk, Emilie Christie, Bruce D. Trapp, Dimitry Ofengeim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Neuroinflammation in the central nervous system (CNS), driven largely by resident phagocytes, has been proposed as a significant contributor to disability accumulation in multiple sclerosis (MS) but has not been addressed therapeutically. Br
Externí odkaz:
https://doaj.org/article/7240258f9fe44a898fcf295ec6f91164
Autor:
Leanna Woods, Rebekah Eden, Sophie Macklin, Jenna Krivit, Rhona Duncan, Helen Murray, Raelene Donovan, Clair Sullivan
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Rural populations experience ongoing health inequities with disproportionately high morbidity and mortality rates, but digital health in rural settings is poorly studied. Our research question was: How does digital health influenc
Externí odkaz:
https://doaj.org/article/3f67d4b9a29c406c9d4544aa778562a6
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-20 (2024)
Abstract Background People experiencing homelessness have increased prevalence, morbidity, and mortality of cardiovascular disease (CVD), attributable to several traditional and non-traditional risk factors. While this burden is well-known, mainstrea
Externí odkaz:
https://doaj.org/article/a5c6c23120634fc6b5641c382482c489
Autor:
Turpin, Dylan, Zhong, Tao, Zhang, Shutong, Zhu, Guanglei, Liu, Jingzhou, Singh, Ritvik, Heiden, Eric, Macklin, Miles, Tsogkas, Stavros, Dickinson, Sven, Garg, Animesh
Multi-finger grasping relies on high quality training data, which is hard to obtain: human data is hard to transfer and synthetic data relies on simplifying assumptions that reduce grasp quality. By making grasp simulation differentiable, and contact
Externí odkaz:
http://arxiv.org/abs/2306.08132