Zobrazeno 1 - 8
of 8
pro vyhledávání: '"P. M. Tsimbouri"'
Autor:
Hannah Donnelly, Ewan Ross, Yinbo Xiao, Rio Hermantara, Aqeel F. Taqi, W. Sebastian Doherty-Boyd, Jennifer Cassels, Penelope. M. Tsimbouri, Karen M. Dunn, Jodie Hay, Annie Cheng, R. M. Dominic Meek, Nikhil Jain, Christopher West, Helen Wheadon, Alison M. Michie, Bruno Peault, Adam G. West, Manuel Salmeron-Sanchez, Matthew J. Dalby
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Long-term reconstituting haematopoietic stem cells (LT-HSCs) are used to treat blood disorders via stem cell transplantation. The very low abundance of LT-HSCs and their rapid differentiation during in vitro culture hinders their clinical ut
Externí odkaz:
https://doaj.org/article/e8984c0b474a49c1b8fa3b60f306f23a
Autor:
Shona J Waddell, María C de Andrés, Penelope M Tsimbouri, Enateri V Alakpa, Maggie Cusack, Matthew J Dalby, Richard OC Oreffo
Publikováno v:
Journal of Tissue Engineering, Vol 9 (2018)
The regenerative potential of skeletal stem cells provides an attractive prospect to generate bone tissue needed for musculoskeletal reparation. A central issue remains efficacious, controlled cell differentiation strategies to aid progression of cel
Externí odkaz:
https://doaj.org/article/f58e2937146846a3a4c323e66e1852de
Autor:
Christopher Allan, Andrew Ker, Carol-Anne Smith, Penelope M Tsimbouri, Juliana Borsoi, Stewart O’Neill, Nikolaj Gadegaard, Matthew J Dalby, RM Dominic Meek
Publikováno v:
Journal of Tissue Engineering, Vol 9 (2018)
The ability to influence stem cell differentiation is highly desirable as it would help us improve clinical outcomes for patients in various aspects. Many different techniques to achieve this have previously been investigated. This concise study, how
Externí odkaz:
https://doaj.org/article/85d3ff5222a046eeb098550e54f8d270
Autor:
Laila Damiati, Marcus G Eales, Angela H Nobbs, Bo Su, Penelope M Tsimbouri, Manuel Salmeron-Sanchez, Matthew J Dalby
Publikováno v:
Journal of Tissue Engineering, Vol 9 (2018)
Titanium (Ti) plays a predominant role as the material of choice in orthopaedic and dental implants. Despite the majority of Ti implants having long-term success, premature failure due to unsuccessful osseointegration leading to aseptic loosening is
Externí odkaz:
https://doaj.org/article/a5a64507a5ce4787a78e11a928dbf4cb
Publikováno v:
Journal of Tissue Engineering, Vol 9 (2018)
The use of biomaterials in orthopaedics for joint replacement, fracture healing and bone regeneration is a rapidly expanding field. Infection of these biomaterials is a major healthcare burden, leading to significant morbidity and mortality. Furtherm
Externí odkaz:
https://doaj.org/article/e77e6abc558949b9b48f5a9826acfa2f
Autor:
Penelope M. Tsimbouri
Publikováno v:
Journal of Functional Biomaterials, Vol 6, Iss 3, Pp 598-622 (2015)
Adult or mesenchymal stem cells (MSCs) have been found in different tissues in the body, residing in stem cell microenvironments called “stem cell niches”. They play different roles but their main activity is to maintain tissue homeostasis and re
Externí odkaz:
https://doaj.org/article/b9ca58ecd7a54ea194606b213928f263
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9092 (2010)
Non-coding RNAs have critical functions in diverse biological processes, particularly in gene regulation. Viruses, like their host cells, employ such functional RNAs and the human cancer associated Epstein-Barr virus (EBV) is no exception. Nearly all
Externí odkaz:
https://doaj.org/article/e41fc435e8e2446c83360b02f9601f02
Autor:
P. M. Tsimbouri, L. Fisher, N. Holloway, T. Sjostrom, A. H. Nobbs, R. M. D Meek, B. Su, M. J. Dalby
Publikováno v:
Scientific Reports.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=issn20452322::e50e9fe6ec5755ef66389df6a7dc1b9b