Zobrazeno 1 - 10
of 18
pro vyhledávání: '"P. M. Sedgwick"'
Autor:
Jorge Escorihuela, Daniel M. Sedgwick, Alberto Llobat, Mercedes Medio-Simón, Pablo Barrio, Santos Fustero
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 1662-1682 (2020)
The Pauson–Khand reaction (PKR) is one of the key methods for the construction of cyclopentenone derivatives, which can in turn undergo diverse chemical transformations to yield more complex biologically active molecules. Despite the increasing ava
Externí odkaz:
https://doaj.org/article/7e7c0875644744019119f2c7659a0b06
Autor:
Cristina Medina-Trillo, Daniel M. Sedgwick, Lidia Herrera, Manuela Beltrán, Ángela Moreno, Pablo Barrio, Luis. M. Bedoya, José Alcamí, Santos Fustero, José Gallego
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Small synthetic molecules mimicking the three-dimensional structure of α-helices may find applications as inhibitors of therapeutically relevant protein-protein and protein-nucleic acid interactions. However, the design and use of multi-fac
Externí odkaz:
https://doaj.org/article/bc755e05db704dcfa42be8ed46552b46
Autor:
Darren A. Brown, Kelly K. O’Brien, Richard Harding, Philip M. Sedgwick, Mark Nelson, Marta Boffito, Agnieszka Lewko
Publikováno v:
PLoS ONE, Vol 17, Iss 5 (2022)
Background The study objectives were to measure disability prevalence and severity, and examine disability risk factors, among adults living with HIV in London, United Kingdom (UK). Methods Self-reported questionnaires were administered: World Health
Externí odkaz:
https://doaj.org/article/2464a5019ae047289a6f18753d1ffe6a
Autor:
Ruth H Keogh, Diana Bilton, Rebecca Cosgriff, Dominic Kavanagh, Oliver Rayner, Philip M Sedgwick
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0213639 (2019)
Cystic fibrosis (CF) is the one of the most common inherited diseases. It affects around 10,000 people in the UK, and the median survival age is 47. Recent developments making use of longitudinal patient registry data are producing more detailed and
Externí odkaz:
https://doaj.org/article/48ec2595905849dd961cb55510b3086d
Publikováno v:
Molecules, Vol 24, Iss 8, p 1569 (2019)
Organofluorine compounds are finding increasing application in a variety of fields such as pharmaceutical, agrochemical, and material sciences. However, given the scarcity of fluorine-containing natural products, advancement in this area depends almo
Externí odkaz:
https://doaj.org/article/f236a01c5f044879933a83145943f165
Publikováno v:
ResearcherID
Summary Background Facial hirsutism in women impairs quality of life (QoL). Laser hair removal (LHR) has been shown to confer significant improvements in QoL for up to 6 months after treatment, but the longer-term benefits have not been investigated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760e715b8e2f5370ee7baf8e04534d2f
https://doi.org/10.1111/ced.12775
https://doi.org/10.1111/ced.12775
Publikováno v:
British Journal of Anaesthesia. 89:711-714
Background Postherpetic neuralgia is a complication of acute herpes zoster characterized by severe pain and paraesthesia in the skin area affected by the initial infection. There is evidence that the N-methyl- d -aspartate receptor is involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8a1b3a8bdeae8366c0d1f80c2dc214
https://doi.org/10.1093/bja/89.5.711
https://doi.org/10.1093/bja/89.5.711
Publikováno v:
The British Journal of Radiology. 72:339-344
A retrospective study was performed to document and compare the radiological appearances of newly diagnosed pulmonary tuberculosis (PTB) in groups of West African patients with (n = 86) and without (n = 106) human immunodeficiency virus (HIV) coinfec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90520022132426c01caed621412bb87
https://doi.org/10.1259/bjr.72.856.10474493
https://doi.org/10.1259/bjr.72.856.10474493
Publikováno v:
British Journal of Psychiatry. 174:135-140
BackgroundBulimia nervosa affects women at a peak age of reproductive functioning, but few studies have examined the impact of pregnancy on bulimia.AimTo examine the impact of pregnancy on symptoms of bulimia nervosa and associated psychopathology.Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf8d18d5b7a23a496c208d80b99a37c
https://doi.org/10.1192/bjp.174.2.135
https://doi.org/10.1192/bjp.174.2.135
Autor:
P. M. Sedgwick
Publikováno v:
Postgraduate Medical Journal. 74:134-138
Summary Adults have an intrinsic body clock which regulates a complex series of rhythms including sleep and wakefulness, fatigue and cognitive ability. This endogenous clock naturally runs more slowly than the solar day and is entrained to a 24-h rhy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29469e11fa736a1f0b85166cdfccc723
https://doi.org/10.1136/pgmj.74.869.134
https://doi.org/10.1136/pgmj.74.869.134