Zobrazeno 1 - 7
of 7
pro vyhledávání: '"P. M. M. Bleeker"'
Publikováno v:
Transfusion Medicine. 5:285-288
SUMMARY. Allele-specific PCR using sequence specific primers (PCR-SSP) is a simple and reliable technique to detect point mutations in genes. We have developed a PCR-SSP to enable the detection of a C-T mutation at position 482 of the GPIb gene and a
Autor:
S. Simsek, A. E. G. K. Von Dem Borne, M. A. M. Overbeeke, P. M. M. Bleeker, C. E. Van Der Schoot, H. T. M. Cuijpers, B. H. W. Faas
Publikováno v:
Blood. 85:2975-2980
Rh (rhesus) D is the dominant antigen of the Rh blood group system. Recent advances in characterization of the nucleotide sequence of the cDNA(s) encoding the Rh D polypeptide allow the determination of the Rh D genotype at the DNA level. This can be
Autor:
A. E. G. K. Von Dem Borne, M. A. M. Overbeeke, P. M. M. Bleeker, H. T. M. Cuijpers, B. H. W. Faas, C. E. Van Der Schoot, S. Simsek
Publikováno v:
Blood. 85:829-832
It has been shown that the Rhesus (Rh) blood group antigens are encoded by two homologous genes: the Rh D gene and the Rh CcEe gene. The Rh CcEe gene encodes different peptides: the Rh C, c, E, and e polypeptides. Only one nucleotide difference has b
Association of a Variable Number of Tandem Repeats (VNTR) in Glycoprotein Ibα and HPA-2 Alloantigens
Publikováno v:
Thrombosis and Haemostasis. 72:757-761
SummaryThe human platelet alloantigen HPA-2 (Koa/Kob) system is involved in two clinical syndromes, neonatal alloimmune thrombocytopenia and platelet transfusion refractoriness. Wb have previously described that the human platelet alloantigens HPA-2a
Autor:
N. M. Faber, A. E. G. K. Von Dem Borne, P. M. M. Bleeker, A. B. J. Vlekke, Roel Goldschmeding, Elly Huiskes, S. Simsek
Publikováno v:
Blood. 81:835-840
UMAN PLATELET alloantigens are of importance in H neonatal alloimmune thrombocytopenia (NAITP), refractoriness to platelet transfusion therapy, and post transfusion purpura (PTP).’ To date, five distinct biallelic platelet “specific” alloantige
Autor:
P. M. M. Bleeker, R. W. A. M. Kuijpers, A. E. G. K. Von Dem Borne, W. H. Ouwehand, D. Christie
Publikováno v:
Blood. 79:283-288
The human platelet-specific alloantigens HPA-2a and HPA-2b (= Kob and Koa) together constitute a biallelic antigen system. The HPA-2 antigens have not, to date, been located on a particular platelet membrane molecule. Here, we describe the localizati
Publikováno v:
British Journal of Haematology. 88:659-661
Summary. We have developed a PCR assay named ASPA (allele-specific primer amplification) to determine the HPA-5a and −5b genotypes. It consists of two PCR-reactions. One primer of each priomer set has a 3’-end nucleotide which is specific for A o