Zobrazeno 1 - 10
of 93
pro vyhledávání: '"P. M. Lydyard"'
Autor:
Kurtis Edwards, Peter M. Lydyard, Nino Kulikova, Tamar Tsertsvadze, Emanuela V. Volpi, Nicholas Chiorazzi, Nino Porakishvili
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-22 (2023)
Abstract Toll-like receptors play a significant role in the innate immune system and are also involved in the pathophysiology of many different diseases. Over the past 35 years, there have been a growing number of publications exploring the role of t
Externí odkaz:
https://doaj.org/article/f06140e300df4a879194db9e189f0eb5
Autor:
M. D. Bodman-Smith, Alimuddin Zumla, A. W. Boylston, Ian Williams, R. Johnstone, P. M. Lydyard
Publikováno v:
Clinical and Experimental Immunology. 130:115-120
SUMMARYIt is still unclear why some patients with HIV progress more slowly than others to developing full blown AIDS. In this study using flow cytometry we have investigated the TCRBV repertoire of peripheral blood T lymphocytes in 17 long-term non-p
Publikováno v:
Lupus. 11:493-500
Systemic lupus erythematosus (SLE) is characterized by B cell hyperactivity and the production of autoantibodies, some of which (antibodies to dsDNA) are thought to be pathogenic. T helper cells drive the production of autoantibodies and the aim of t
Publikováno v:
Immunology. 99:498-503
Some gammadelta T cells express a receptor for the Fc portion of immunoglobulin G (FcgammaRIII - CD16). The relevance of this Fc receptor to gammadelta T-cell function is at present unclear. Our previous studies have shown that gammadelta T cells exp
Publikováno v:
Scopus-Elsevier
SUMMARY The ability of an anti-phospholipid (LJ1) and an anti-β2-GPI (RSP-57) human MoAb to bind to apoptotic but not viable cells was demonstrated in this study. Both MoAbs were derived from patients with systemic lupus erythematosus and anti-phosp
Autor:
K. B. Bodman-Smith, Peter J. Delves, H. Hirota, Jeremy J. Keusch, M. S. Chesnutt, David Wofsy, P. M. Lydyard, P. A. Jeddi, Tetsuya Taga
Publikováno v:
Immunology. 98:475-480
SUMMARY The effect on murine immunoglobulin G (IgG) glycosylation of altering IgG production in vivo was assessed in interleukin (IL)-6 transgenic and CD4 knockout mice. C57BL/6 mice carrying the IL-6 transgene showed increased levels of circulating
Autor:
Pierre Youinou, P. M. Lydyard, Maryvonne Dueymes, Jacques-Olivier Pers, R Le Corre, Christophe Jamin
Publikováno v:
International Immunology. 9:1001-1009
B cells expressing CD5 also carry its ligand, CD72. As an approach to understanding the role of CD5 and CD72 on B cells, we have examined the association of CD72 with CD5 and slgM by modulation/co-modulation and capping/co-capping following ligation
Publikováno v:
Scandinavian Journal of Immunology. 45:145-150
The authors used murine pregnancy as a model to investigate the regulation of IgG glycosylation. Pregnancy is associated with decreased levels of circulating IgG. The oligosaccharides on this IgG from late (day 15), but not early (day 8), pregnant Ba
Autor:
G. G. de Sa Oliveira, Robert N. Barker, P. M. Lydyard, Shozo Izui, Christopher J. Elson, C. T. Ravirajan, Rizgar A. Mageed
Publikováno v:
Clinical and Experimental Immunology, Vol. 105, No 2 (1996) pp. 313-320
The specificities of a panel of erythrocyte-reactive MoAbs derived from NZB mice with autoimmune haemolytic anaemia (AIHA) were determined by immunoprecipitation and immunoblotting. Of the eight antibodies, two (IgG1 MoAb 105-2H and IgG2a MoAb 34-3C)
Autor:
B. Yuksel, R. C. A. A. Van Schie, P. M. Lydyard, A. Greenough, Michael W. Fanger, M. Maeda, Paul M. Guyre
Publikováno v:
Clinical and Experimental Immunology. 103:343-347
The immature neonatal immune system is thought to result in increased risk of infection. Receptors for the Fc moiety of IgG (Fc gamma R) are important in antibody-mediated clearance of microbes by granulocytes and monocytes/macrophages. As an approac