Zobrazeno 1 - 10
of 20
pro vyhledávání: '"P. M. C. Wright"'
Autor:
J. H. Proost, P. M. C. Wright
Publikováno v:
European Journal of Anaesthesiology. 18:83-89
Autor:
R. H. G. Van Den Brom, G. J. Roest, J. I. Andrews, P. M. C. Wright, Klaus T. Olkkola, N Kumar
Publikováno v:
Acta Anaesthesiologica Scandinavica. 43:4-8
Background: Rocuronium has an onset of action more rapid than other non-depolarizing neuromuscular blocking agents, but it is unclear whether it and succinylcholine give equivalent intubating conditions during rapid-sequence induction of anaesthesia.
Autor:
P. M. C. Wright
Publikováno v:
British Journal of Anaesthesia. 80:488-501
To study the time course of drug effects in biological systems requires appreciation of drug disposition within the organism; the science of pharmacokinetics. We need also to appreciate how drug effects relate to their concentration in plasma and at
Autor:
M. Cross, H. Dale, P. A. Taylor, P. M. C. Wright, P. C. M. Vijn, P. Boen, G. Voortman, J. R. Sneyd, D. Harris
Publikováno v:
British Journal of Anaesthesia. 79:433-439
ORG 21465 has been found to possess anaesthetic properties in humans and its pharmacokinetics are known. We performed this study to confirm the characteristics associated with its administration and to define its pharmacodynamic profile, in particula
Publikováno v:
Acta Anaesthesiologica Scandinavica. 38:808-812
Twenty-one ASA I or II patients undergoing upper abdominal surgery were studied for 24 hours after operation. They were entered into a prospective, randomised study of patient-controlled intravenous morphine compared with continuous thoracic epidural
Continuous thoracic epidural fentanyl for post-thoracotomy pain relief: with or without bupivacaine?
Publikováno v:
Anaesthesia. 46:732-736
Twenty-five ASA 1 or 2 patients undergoing thoracotomy were entered into a prospective, randomised, double-blind study comparing thoracic epidural fentanyl alone and thoracic epidural fentanyl combined with 0.2% bupivacaine. Pain relief, pulmonary fu
Publikováno v:
Allergy. 59(11)
Autor:
J. M. Hunter, J. P. Hing, P. M C Wright, Brian J. Pollard, J. M. Scott, K. G. Mills, G. Danjoux
Publikováno v:
British journal of anaesthesia. 83(5)
We have studied the pharmacodynamics and pharmacokinetics of rapacuronium (Org 9487) in 70 healthy patients. Neuromuscular transmission was monitored using TOF stimulation of the ulnar nerve and mechanomyography of the adductor pollicis muscle. Half
Publikováno v:
Anaesthesia. 46:1013-1015
The effect of two doses of clonidine on forearm blood flow was compared with an inert treatment using mercury strain gauge venous occlusive plethysmography. In the clonidine treated groups, forearm blood flow was unaffected in the resting state, but
Autor:
P. Thompson, M. M. Weideman, P. M. C. Wright, M. Cross, G. Voortman, C. J. H. Andrews, C. J. Daniell, J. R. Sneyd
Publikováno v:
British journal of anaesthesia. 79(4)
Ten male volunteers received a 1-min i.v. infusion of a new water soluble steroid anaesthetic agent, ORG 21465. Individuals received doses ranging from 0.8 to 1.8 mg kg-1. All subjects experienced venous pain at the site of injection; those receiving