Zobrazeno 1 - 10
of 53
pro vyhledávání: '"P. M. Blatt"'
Autor:
Cheng Liu, Sarah Stevens, Heleen Roose, Kha Le, Kristina Rekstyte-Matiene, Kusum Gupta, Sandra Chang, Vladimir Serebryany, Lillian Adame, Antitsa Stoycheva, Lawrence M Blatt, Leonid Beigelman, Sushmita Chanda, David B Smith, Julian A Symons, Andreas Jekle, Tongfei Wu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/c170486abb824f06906cb4f47c056214
Autor:
Cheng Liu, Sarah Stevens, Heleen Roose, Kha Le, Kristina Rekstyte-Matiene, Kusum Gupta, Sandra Chang, Vladimir Serebryany, Lillian Adame, Antitsa Stoycheva, Lawrence M Blatt, Leonid Beigelman, Sushmita Chanda, David B Smith, Julian A Symons, Andreas Jekle, Tongfei Wu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/875cd85b72334cbe84a2cbfc4b70946f
Autor:
C. Cheng Kao, Yuchun Nie, Suping Ren, N. Tilani T.S. De Costa, Rajendra K. Pandey, Jin Hong, David B. Smith, Julian A. Symons, Leonid Beigelman, Lawrence M. Blatt
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 335-348 (2022)
A functional cure of chronic hepatitis B requires eliminating the hepatitis B virus (HBV)-encoded surface antigen (HBsAg), which can suppress immune responses. STOPS are phosphorothioated single-stranded oligonucleotides containing novel chemistries
Externí odkaz:
https://doaj.org/article/3009f7da2edc4ff9b9530dca559fa931
Autor:
Dirk Jochmans, Cheng Liu, Kim Donckers, Antitsa Stoycheva, Sandro Boland, Sarah K. Stevens, Chloe De Vita, Bert Vanmechelen, Piet Maes, Bettina Trüeb, Nadine Ebert, Volker Thiel, Steven De Jonghe, Laura Vangeel, Dorothée Bardiot, Andreas Jekle, Lawrence M. Blatt, Leonid Beigelman, Julian A. Symons, Pierre Raboisson, Patrick Chaltin, Arnaud Marchand, Johan Neyts, Jerome Deval, Koen Vandyck
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT The SARS-CoV-2 main protease (3CLpro) has an indispensable role in the viral life cycle and is a therapeutic target for the treatment of COVID-19. The potential of 3CLpro-inhibitors to select for drug-resistant variants needs to be establish
Externí odkaz:
https://doaj.org/article/68b3f8dcc3b24cffa15d8cab99c36119
Autor:
Xuan G Luong, Sarah K Stevens, Andreas Jekle, Tse-I Lin, Kusum Gupta, Dinah Misner, Sushmita Chanda, Sucheta Mukherjee, Caroline Williams, Antitsa Stoycheva, Lawrence M Blatt, Leonid N Beigelman, Julian A Symons, Pierre Raboisson, David McGowan, Koen Vandyck, Jerome Deval
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0240338 (2020)
Thyroid hormones are important modulators of metabolic activity in mammals and alter cholesterol and fatty acid levels through activation of the nuclear thyroid hormone receptor (THR). Currently, there are several THRβ agonists in clinical trials fo
Externí odkaz:
https://doaj.org/article/9888716071a5408e90bb5d9370ea3a38
Autor:
Matthew W McClure, Elina Berliba, Tengiz Tsertsvadze, Adrian Streinu-Cercel, Leen Vijgen, Béatrice Astruc, Alain Patat, Christopher Westland, Sushmita Chanda, Qingling Zhang, Thomas N Kakuda, Jennifer Vuong, Nick Khorlin, Leonid Beigelman, Lawrence M Blatt, John Fry
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204974 (2018)
BACKGROUND:The nucleotide analog AL-335 is a pangenotypic hepatitis C virus (HCV) nonstructural protein (NS)5B inhibitor being evaluated as treatment for chronic HCV infection. METHODS:This three-part randomized, double-blind study evaluated the safe
Externí odkaz:
https://doaj.org/article/734ab2d56f1a434cbd65736ecb72aa86
Autor:
Jerome Deval, Jin Hong, Guangyi Wang, Josh Taylor, Lucas K Smith, Amy Fung, Sarah K Stevens, Hong Liu, Zhinan Jin, Natalia Dyatkina, Marija Prhavc, Antitsa D Stoycheva, Vladimir Serebryany, Jyanwei Liu, David B Smith, Yuen Tam, Qingling Zhang, Martin L Moore, Rachel Fearns, Sushmita M Chanda, Lawrence M Blatt, Julian A Symons, Leo Beigelman
Publikováno v:
PLoS Pathogens, Vol 11, Iss 6, p e1004995 (2015)
Respiratory syncytial virus (RSV) causes severe lower respiratory tract infections, yet no vaccines or effective therapeutics are available. ALS-8176 is a first-in-class nucleoside analog prodrug effective in RSV-infected adult volunteers, and curren
Externí odkaz:
https://doaj.org/article/2d5adaa211d8415eabca3c2fc3171ff6
Publikováno v:
Ecology and Society, Vol 21, Iss 4, p 39 (2016)
Many challenges we face today are intimately linked to and derive from the biophysical and ecological degradation underway in almost all ecosystems on Earth. Responding effectively will require (1) changes in our behavior as citizens, parents, and co
Externí odkaz:
https://doaj.org/article/fd13c193f6a54366af8f78fb9239e7bb
Autor:
P. M. Blatt, Gilbert C. White
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 15(12)
Autor:
Gilbert C. White, P. M. Blatt
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 12(4)