Zobrazeno 1 - 7
of 7
pro vyhledávání: '"P. M. Berguer"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Brucella lumazine synthase (BLS) is a homodecameric protein that activates dendritic cells via toll like receptor 4, inducing the secretion of pro-inflammatory cytokines and chemokines. We have previously shown that BLS has a therapeutic eff
Externí odkaz:
https://doaj.org/article/c1e29dd9f660401a91056f73c081b0bc
Autor:
Sabrina E. Vinzón, María V. Lopez, Eduardo G. A. Cafferata, Ariadna S. Soto, Paula M. Berguer, Luciana Vazquez, Leonora Nusblat, Andrea V. Pontoriero, Eduardo M. Belotti, Natalia R. Salvetti, Diego L. Viale, Ariel E. Vilardo, Martin M. Avaro, Estefanía Benedetti, Mara L. Russo, María E. Dattero, Mauricio Carobene, Maximiliano Sánchez-Lamas, Jimena Afonso, Mauro Heitrich, Alejandro E. Cristófalo, Lisandro H. Otero, Elsa G. Baumeister, Hugo H. Ortega, Alexis Edelstein, Osvaldo L. Podhajcer
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract COVID-19 vaccines were originally designed based on the ancestral Spike protein, but immune escape of emergent Variants of Concern (VOC) jeopardized their efficacy, warranting variant-proof vaccines. Here, we used preclinical rodent models t
Externí odkaz:
https://doaj.org/article/ba99e3be03244ebfae597386425015da
Autor:
M. Verónica López, Sabrina E. Vinzón, Eduardo G. A. Cafferata, Felipe J. Núñez, Ariadna Soto, Maximiliano Sanchez-Lamas, M. Jimena Afonso, Diana Aguilar-Cortes, Gregorio D. Ríos, Juliana T. Maricato, Carla T. Braconi, Vanessa B. Silveira, Tatiane M. Andrad, Tatiana C. S. Bonetti, Luiz M. Ramos Janini, Manoel J. B. C. Girão, Andrea S. Llera, Karina A. Gomez, Hugo H. Ortega, Paula M. Berguer, Osvaldo L. Podhajcer
Publikováno v:
Vaccines, Vol 9, Iss 10, p 1106 (2021)
Most approved vaccines against COVID-19 have to be administered in a prime/boost regimen. We engineered a novel vaccine based on a chimeric human adenovirus 5 (hAdV5) vector. The vaccine (named CoroVaxG.3) is based on three pillars: (i) high expressi
Externí odkaz:
https://doaj.org/article/b0086f266e2e4a949a588004e905c559
Autor:
Andrés H Rossi, Ana Farias, Javier E Fernández, Hernán R Bonomi, Fernando A Goldbaum, Paula M Berguer
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126827 (2015)
Brucella Lumazine Synthase (BLS) is a highly immunogenic decameric protein which can accept the fusion of foreign proteins at its ten N-termini. These chimeras are very efficient to elicit systemic and oral immunity without adjuvants. BLS signaling v
Externí odkaz:
https://doaj.org/article/c057505ef5c54e8db5589a204193343d
Autor:
Paula M Berguer, Vanina A Alzogaray, Andrés Hugo Rossi, Juliana Mundiñano, Isabel Piazzon, Fernando A Goldbaum
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45705 (2012)
Lumazine synthase from Brucella spp. (BLS) is a highly immunogenic decameric protein. It is possible to insert foreign peptides or proteins at its ten-amino acid termini. These chimeras elicit systemic and oral immunity without adjuvants, which are c
Externí odkaz:
https://doaj.org/article/65ff7c58e58e402bb16bca667af6aa7b
Autor:
Juliana Mundiñano, Paula M Berguer, Gabriel Cabrera, Daniela Lorenzo, Irene Nepomnaschy, Isabel Piazzon
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15694 (2010)
Superantigens bind to major histocompatibility complex class II molecules and interact with T cells expressing a particular T cell receptor Vβ inducing a strong proliferation/deletion response of the superantigen-reactive T cells. However, there hav
Externí odkaz:
https://doaj.org/article/3611680d05b94c0c9352b36d3466c280
Autor:
por Iacobo Cro[m]berguer..., Francisco Guerra, Rafael Floranes BHI BH FG 2035, Fernando Fernández de Velasco BHI BH FG 2035, Jacobo Cromberger (Sevilla)
Publikováno v:
Universidad Complutense de Madrid.
Externí odkaz:
http://www.manuscriptorium.com/apps/index.php?direct=record&pid=UCM___-UCM___BH_FG_2035__3R58C9E-es