Zobrazeno 1 - 10
of 25
pro vyhledávání: '"P. M. Beardsley"'
Autor:
Gordon T. Brown, Sangeethabalasri Pugazhendhi, Robert M. Beardsley, John W. Karth, Peter A. Karth, Allan A. Hunter
Publikováno v:
International Journal of Retina and Vitreous, Vol 6, Iss 1, Pp 1-6 (2020)
Abstract Background To evaluate visual and safety outcomes for 25-gauge (25G) and 27-gauge (27G) micro-incision vitrectomy platforms (MIVS) for the treatment of epiretinal membrane and full-thickness macular holes. Methods Retrospective analysis of a
Externí odkaz:
https://doaj.org/article/080468dbd3ff40e3a555b4d5fdf743ba
Autor:
Sarah B. Gitto, Jordan M. Beardsley, Sai Preethi Nakkina, Jeremiah L. Oyer, Kathryn A. Cline, Sally A. Litherland, Alicja J. Copik, Amr S. Khaled, Na’im Fanaian, J. Pablo Arnoletti, Deborah A. Altomare
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background While inflammation is associated with pancreatic cancer, the underlying mechanisms leading to cancer initiation are still being delineated. Eosinophils may promote or inhibit tumor growth, although the specific role in pancreatic
Externí odkaz:
https://doaj.org/article/182a76e644af4cc9a41cfff458d20fb4
Autor:
Mario de la Fuente Revenga, Bohan Zhu, Christopher A. Guevara, Lynette B. Naler, Justin M. Saunders, Zirui Zhou, Rudy Toneatti, Salvador Sierra, Jennifer T. Wolstenholme, Patrick M. Beardsley, George W. Huntley, Chang Lu, Javier González-Maeso
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109836- (2021)
Summary: Clinical evidence suggests that rapid and sustained antidepressant action can be attained with a single exposure to psychedelics. However, the biological substrates and key mediators of psychedelics’ enduring action remain unknown. Here, w
Externí odkaz:
https://doaj.org/article/43705a14b3dc480c8aba3ee0cb75a2bd
Publikováno v:
Evolution: Education and Outreach, Vol 11, Iss 1, Pp 1-14 (2018)
Abstract Background While recent research indicates that using human examples can be an engaging way to teach core evolutionary concepts such as natural selection and phylogenetic thinking, teachers still face potential conflicts and challenges that
Externí odkaz:
https://doaj.org/article/5ddf568048554374baa05bc9ddcc7ae3
Autor:
Kathleen J. Roth, Jody Bintz, Nicole I. Z. Wickler, Connie Hvidsten, Joseph Taylor, Paul M. Beardsley, Arlo Caine, Christopher D. Wilson
Publikováno v:
International Journal of STEM Education, Vol 4, Iss 1, Pp 1-24 (2017)
Abstract Background Most studies of teacher professional development (PD) do not rigorously test impact on teaching practice and student learning. This makes it difficult to define what is truly “effective.” The Science Teachers Learning from Les
Externí odkaz:
https://doaj.org/article/0bd745f55bb44800931533ae3362f472
Autor:
R, Depoortère, J, Bergman, P M, Beardsley, R I, Desai, C A, Paronis, D M, Walentiny, M A, Varney, A, Newman-Tancredi
Publikováno v:
Neuropharmacology
NLX-112 (a.k.a. F13640 or befiradol) exhibits nanomolar affinity, exceptional selectivity and biased agonism at serotonin 5-HT(1A) receptors. NLX-112 displays robust analgesic activity in a number of rodent models of pain, and is currently developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2650e73c59966851666fa136a009a5af
https://pubmed.ncbi.nlm.nih.gov/35276118
https://pubmed.ncbi.nlm.nih.gov/35276118
Publikováno v:
British journal of pharmacology. 169(3)
Pitolisant, a histamine H₃ receptor inverse agonist/antagonist is currently under Phase III clinical trials for treatment of excessive daytime sleepiness namely in narcoleptic patients. Its drug abuse potential was investigated using in vivo models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b87bf723143251bcf1562ff8530d5fb
https://pubmed.ncbi.nlm.nih.gov/23472741
https://pubmed.ncbi.nlm.nih.gov/23472741
Autor:
C. D. Cook, P. M. Beardsley
Publikováno v:
Behavioural pharmacology. 15(1)
Dopamine (DA) D2/3 receptor agonists have been shown to attenuate the behavioral effects of mu opioid agonists. This study was designed to examine the modulatory actions of the D2/3 agonists quinelorane, quinpirole and (+/-)-2-dipropylamino-7-hydroxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0839182471b193c4098c8b3aa590ca30
https://pubmed.ncbi.nlm.nih.gov/15075629
https://pubmed.ncbi.nlm.nih.gov/15075629
Publikováno v:
Journal of medicinal chemistry. 44(6)
In our effort to develop a pharmacotherapy for the treatment of cocaine addiction, we embarked on synthesizing novel molecules targeting the dopamine transporter (DAT) molecule in the brain as DAT has been implicated strongly in the reinforcing effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ae8225cda428d9877d58dea5b1c39ba
https://pubmed.ncbi.nlm.nih.gov/11300876
https://pubmed.ncbi.nlm.nih.gov/11300876
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(1)
Several reports have indicated that N-methyl-D-aspartate (NMDA) receptor antagonists prevent the development of analgesic tolerance to opiates. Some effects of opiates, such as their discriminative stimulus effects, are known to be more resistant to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44e9d826e975f94b276afe4aa3c81da2
https://pubmed.ncbi.nlm.nih.gov/10381755
https://pubmed.ncbi.nlm.nih.gov/10381755