Zobrazeno 1 - 10
of 12
pro vyhledávání: '"P. M. Appasamy"'
Publikováno v:
The Journal of Immunology. 158:5744-5750
IL-7, a cytokine produced by bone marrow and thymic stroma, is a growth factor for B and T lymphocytes very early in their development. The IL-7R is a heterodimer of an alpha-chain that specifically binds IL-7 and the common gamma-chain, gamma(c), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f83c6014f9856831741849a257a7eef
https://doi.org/10.4049/jimmunol.158.12.5744
https://doi.org/10.4049/jimmunol.158.12.5744
Autor:
Albert B. DeLeo, P M Appasamy, Ettore Appella, H Sakamoto, Michael T. Lotze, Jose I. Mayordomo, Walter J. Storkus, C. M. De Cesare, D J Loftus
Publikováno v:
The Journal of Experimental Medicine
The BALB/c Meth A sarcoma carries a p53 missense mutation at codon 234, which occurs in a peptide, termed 234CM, capable of being presented to cytotoxic T lymphocytes (CTL) by H-2Kd molecules (Noguchi, Y., E.C. Richards, Y.-T. Chen, and L.J. Old. 199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68844b5db563607336a91149c061c892
https://doi.org/10.1084/jem.183.4.1357
https://doi.org/10.1084/jem.183.4.1357
Autor:
P M Appasamy
Publikováno v:
The Journal of Immunology. 149:1649-1656
IL-7 has previously been shown to stimulate proliferation of immature CD4-CD8- thymocytes from fetal and adult mice. We show that IL-7 mRNA levels are much higher in the day-14 fetal thymus than in the adult thymus, i.e., when the thymus is primarily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b8c32dd826949975a99d8be51b93be3
https://doi.org/10.4049/jimmunol.149.5.1649
https://doi.org/10.4049/jimmunol.149.5.1649
Autor:
P M, Appasamy
Publikováno v:
Cytokines, cellularmolecular therapy. 5(1)
Interleukin 7 (IL-7) is a stromal cell-derived cytokine that stands out as being the only cytokine identified to date on which development of B and T lymphocytes is absolutely dependent. IL-7 functions primarily as a growth and antiapoptosis factor f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::998c6280dd72cf1edd9c0ed3f47ef403
https://pubmed.ncbi.nlm.nih.gov/10390077
https://pubmed.ncbi.nlm.nih.gov/10390077
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(12)
IL-7, a cytokine produced by bone marrow and thymic stroma, is a growth factor for B and T lymphocytes very early in their development. The IL-7R is a heterodimer of an alpha-chain that specifically binds IL-7 and the common gamma-chain, gamma(c), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::873bc301ff5ad33ee12a23aea98aafcb
https://pubmed.ncbi.nlm.nih.gov/9190924
https://pubmed.ncbi.nlm.nih.gov/9190924
Publikováno v:
Natural immunity. 15(5)
Natural killer (NK) cells and a T cell subset express NKR-P1s; however, it is not known if NKR-P1s on these cells are homologous. By molecular and biochemical means, we determined that NKR-P1s on NK cells and T cells were similar. Also, sequencing of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4977b51756a5950b4974247ea306e9f5
https://pubmed.ncbi.nlm.nih.gov/9390275
https://pubmed.ncbi.nlm.nih.gov/9390275
Publikováno v:
Natural immunity. 14(2)
From sorted rat NKR-P1bright/T cell receptor (TCR) alpha beta-cells, we established interleukin (IL)-2-dependent cell lines with the morphology, phenotype and function of natural killer (NK) cells. The cell lines NKbr11.3 and NKbr1.28 had large-granu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de2a5dc6eb798abf95ef995f08b72b52
https://pubmed.ncbi.nlm.nih.gov/8601077
https://pubmed.ncbi.nlm.nih.gov/8601077
Autor:
P M, Appasamy
Publikováno v:
Cancer treatment and research. 80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5833df691b976dba11f64bf9475bface
https://pubmed.ncbi.nlm.nih.gov/8821580
https://pubmed.ncbi.nlm.nih.gov/8821580
Publikováno v:
Natural immunity. 14(3)
We have recently begun investigating the effects of prolactin (PRL) on the function, or growth and differentiation of rat NK cells. Initially, we sought to determine the expression of a receptor for PRL (PRLr) on rat NK cells and to determine the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::817c0bc12d0c00de33dfc81cf0b3a977
https://pubmed.ncbi.nlm.nih.gov/8832898
https://pubmed.ncbi.nlm.nih.gov/8832898
Autor:
V, Balasubramaniam, P M, Appasamy
Publikováno v:
Developmental and comparative immunology. 18(3)
Murine T cells bearing the gamma delta T-cell receptor (gamma delta TCR) are the major lymphocyte subset in the thymus early in fetal development, and postnatally they are the major population of T cells in the epithelia of nonlymphoid tissues includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::591aa239a457b757a4e442e5f36c61fe
https://pubmed.ncbi.nlm.nih.gov/8001697
https://pubmed.ncbi.nlm.nih.gov/8001697