Zobrazeno 1 - 10
of 100
pro vyhledávání: '"P. M. Abdul-Muneer"'
Autor:
P. M. Abdul-Muneer
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 4, p 81 (2023)
In this review, we discuss the possibility and feasibility of nuclear factor erythroid 2-related factor 2 (Nrf2) as a therapeutic target to minimize the devastating effects of a brain injury. To complete this review, comprehensive literature searches
Externí odkaz:
https://doaj.org/article/d346d7b779384a5fa547c65c19de505d
Publikováno v:
Brain Sciences, Vol 8, Iss 1, p 11 (2018)
Traumatic brain injury (TBI) can result in persistent sensorimotor and cognitive deficits, which occur through a cascade of deleterious pathophysiological events over time. In this study, we investigated the hypothesis that neurodegeneration caused b
Externí odkaz:
https://doaj.org/article/60c481dcaf4d4921bfaf74947a04f908
Publikováno v:
Journal of Molecular Medicine. 97:1627-1641
Recent studies from our group and others have demonstrated that oxidative stress, Ca2+ signaling, and neuroinflammation are major mechanisms contributing to post-traumatic neurodegeneration. The present study investigated the mechanisms of regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7403e9295dd6b51ceb8b9792782dc982
https://doi.org/10.1007/s00109-019-01851-4
https://doi.org/10.1007/s00109-019-01851-4
Publikováno v:
Experimental Neurology. 317:260-270
The blood-brain barrier (BBB) constitutes a neurovascular unit formed by microvascular endothelial cells, pericytes, and astrocytes. Brain pericytes are important regulators of BBB integrity, permeability, and blood flow. Pericyte loss has been impli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa3d22795c6022fb47b4b474be0d054
https://doi.org/10.1016/j.expneurol.2019.03.014
https://doi.org/10.1016/j.expneurol.2019.03.014
Autor:
P. M. Abdul-Muneer, Saurav Bhowmick
Publikováno v:
Journal of neuropathology and experimental neurology. 80(2)
The long-term disabilities associated with spinal cord injury (SCI) are primarily due to the absence of robust neuronal regeneration and functional plasticity. The inability of the axon to regenerate after SCI is contributed by several intrinsic fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2294b090a552f7a250e5f7a99829458
https://pubmed.ncbi.nlm.nih.gov/33367790
https://pubmed.ncbi.nlm.nih.gov/33367790
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19258 (2011)
Methamphetamine (METH), an addictive psycho-stimulant drug exerts euphoric effects on users and abusers. It is also known to cause cognitive impairment and neurotoxicity. Here, we hypothesized that METH exposure impairs the glucose uptake and metabol
Externí odkaz:
https://doaj.org/article/bc3ae6f402f84d7f83f460f3f694bfa7
Publikováno v:
Molecular Neurobiology. 55:5901-5912
Angiotensin II (Ang II) is a mediator of oxidative stress via activation/induction of reactive oxygen and nitrogen species-generating enzymes, NADPH oxidase (NOX) and inducible nitric oxide synthase (iNOS). We investigated the hypothesis that overpro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5538b505bd22fc0914de6aadbbf675f
https://doi.org/10.1007/s12035-017-0812-z
https://doi.org/10.1007/s12035-017-0812-z
Autor:
Veera D’Mello, Christina Finn, Saurav Bhowmick, P. M. Abdul-Muneer, Nizmi Ponery, Anitha Malat, Danielle Caruso
Publikováno v:
eNeuro
Intercellular adhesion molecule-1 (ICAM-1) promotes adhesion and transmigration of circulating leukocytes across the blood-brain barrier. Traumatic brain injury (TBI) causes transmigrated immunocompetent cells to release mediators (LFA-1 and Mac-1) t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f796f4281367b5719c323dd2256760c
https://doi.org/10.1523/eneuro.0242-21.2021
https://doi.org/10.1523/eneuro.0242-21.2021
Publikováno v:
Molecular neurobiology. 56(2)
Mitogen-activated protein (MAP) kinases are serine/threonine protein kinases that play a critical role in signal transduction and are activated by phosphorylation in response to a variety of pathophysiology stimuli. While MAP kinase signaling has a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04051535d3873d887557f7b26479c1ed
https://pubmed.ncbi.nlm.nih.gov/29873042
https://pubmed.ncbi.nlm.nih.gov/29873042
Publikováno v:
Journal of Neuroscience Methods. 240:77-88
A central problem in neuroscience is elucidating synaptic connections, the connectome. Because mammalian forebrains contain many neurons, labeling specific neurons with unique tags is desirable. A novel technology, Brainbow, creates hundreds of hues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4396d7f3765738dc2fe0a8d8d79eff4d
https://doi.org/10.1016/j.jneumeth.2014.11.009
https://doi.org/10.1016/j.jneumeth.2014.11.009