Zobrazeno 1 - 10
of 1 816
pro vyhledávání: '"P. Mäser"'
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 2, Pp 159-164 (2018)
Trypanosoma congolense is a protozoan parasite that is transmitted by tsetse flies, causing African Animal Trypanosomiasis, also known as Nagana, in sub-Saharan Africa. Nagana is a fatal disease of livestock that causes severe economic losses. Two dr
Externí odkaz:
https://doaj.org/article/82930ea5d9d641b3a58aebf319675069
Autor:
Elena Cesar-Rodo, Baptiste Dupouy, Cécile Häberli, Jean-Marc Strub, David L. Williams, Pascal Mäser, Matthias Rottmann, Jennifer Keiser, Don Antoine Lanfranchi, Elisabeth Davioud-Charvet
Publikováno v:
Molecules, Vol 29, Iss 22, p 5268 (2024)
Ψ-1,4-naphthoquinones (Ψ-NQ) are non-quinoid compounds in which aromaticity—found in 1,4-naphthoquinones—is broken by the introduction of an angular methyl at C-4a or -8a. This series was designed to act as prodrugs of 1,4-naphthoquinones in an
Externí odkaz:
https://doaj.org/article/cded9c06b8374dad9697e51b4130bc42
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Antimalarial resistance to the first-line partner drug piperaquine (PPQ) threatens the effectiveness of artemisinin-based combination therapy. In vitro piperaquine resistance is characterized by incomplete growth inhibition, i.e. increased parasite g
Externí odkaz:
https://doaj.org/article/c86a51b4ecc24b17b0c575f258d5446c
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 23, Iss , Pp 44-53 (2023)
Suramin is one of the oldest drugs in use today. It is still the treatment of choice for the hemolymphatic stage of African sleeping sickness caused by Trypanosoma brucei rhodesiense, and it is also used for surra in camels caused by Trypanosoma evan
Externí odkaz:
https://doaj.org/article/3beabf9372d546fc86fc9893d69c7c1e
Autor:
Sebastian Walesch, Ronald Garcia, Abdelhalim B. Mahmoud, Fabian Panter, Sophie Bollenbach, Pascal Mäser, Marcel Kaiser, Daniel Krug, Rolf Müller
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTIn the past century, microbial natural products have proven themselves to be substantial and fruitful sources of anti-infectives. In addition to the well-studied Actinobacteria, understudied bacterial taxa like the Gram-negative myxobacteria
Externí odkaz:
https://doaj.org/article/b6e3d736a4d74369a8c28d3ceeea480d
Autor:
Lore Baert, Serena Rudy, Mélanie Pellisson, Thierry Doll, Romina Rocchetti, Marcel Kaiser, Pascal Mäser, Matthias Müller
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 1, p e0011559 (2024)
The parasite Leishmania donovani is one of the species causing visceral leishmaniasis in humans, a deadly infection claiming up to 40,000 lives each year. The current drugs for leishmaniasis treatment have severe drawbacks and there is an urgent need
Externí odkaz:
https://doaj.org/article/0559f775e19b434eb173945480fa2e87
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Nina Vahekeni, Théo Brillatz, Marjan Rahmaty, Monica Cal, Sonja Keller-Maerki, Romina Rocchetti, Marcel Kaiser, Sibylle Sax, Kevin Mattli, Evelyn Wolfram, Laurence Marcourt, Emerson Ferreira Queiroz, Jean-Luc Wolfender, Pascal Mäser
Publikováno v:
Molecules, Vol 29, Iss 7, p 1611 (2024)
Folk medicine is widely used in Angola, even for human African trypanosomiasis (sleeping sickness) in spite of the fact that the reference treatment is available for free. Aiming to validate herbal remedies in use, we selected nine medicinal plants a
Externí odkaz:
https://doaj.org/article/af4925c1057c4951af249559e86d85a1
Autor:
Sarah Ceylan Krassnig, Marina Mäser, Nicola Anna Probst, Jens Werner, Charlotte Schlett, Nina Schumann, Gudrun von Scheven, Aswin Mangerich, Alexander Bürkle
Publikováno v:
Toxicology Reports, Vol 10, Iss , Pp 171-189 (2023)
Chlorambucil (CLB) belongs to the class of nitrogen mustards (NMs), which are highly reactive bifunctional alkylating agents and were the first chemotherapeutic agents developed. They form DNA interstrand crosslinks (ICLs), which cause a blockage of
Externí odkaz:
https://doaj.org/article/4cf2e1ac875444ff9edb92dd65be03db