Zobrazeno 1 - 10
of 38
pro vyhledávání: '"P. L. SKIPPER"'
Autor:
P. L. Skipper, S. K. Hammond, J. Coghlin, Peter H. Gann, K. Taghizadeh, M. Paul, S. R. Tannenbaum
Publikováno v:
JNCI Journal of the National Cancer Institute. 85:474-478
A potent bladder carcinogen for workers in the dye industry, 4-aminobiphenyl (4-ABP), is present in environmental tobacco smoke and has been shown to bond covalently with hemoglobin.The goal of this study was to examine the relationship between expos
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 9(7)
The ubiquitous environmental carcinogen benzo[a]pyrene (BaP) is metabolized in vivo in humans to its ultimate carcinogenic form of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE). Mouse skin tumorigenicity studies indicate that the
Autor:
N M, Probst-Hensch, D A, Bell, M A, Watson, P L, Skipper, S R, Tannenbaum, K K, Chan, R K, Ross, M C, Yu
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 9(6)
Aminobiphenyls (ABPs) in tobacco have been implicated in bladder cancer etiology in smokers. N-Acetylation of ABPs in the liver, predominantly by the N-acetyltransferase 2 (NAT2) isozyme, represents a detoxification pathway, whereas O-acetylation of
Autor:
L C, Kidd, W G, Stillwell, M C, Yu, J S, Wishnok, P L, Skipper, R K, Ross, B E, Henderson, S R, Tannenbaum
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 8(5)
Meats, such as beef, pork, poultry, and fish, cooked at high temperatures produce heterocyclic aromatic amines, which have been implicated indirectly as etiological agents involved in colorectal and other cancers in humans. This study examined the ur
Publikováno v:
The Journal of Organic Chemistry. 55:2918-2920
New syntheses of cyclopenta(cd)pyrene 3,4-oxide (CPPE) and 4-pyrenylacetic acid, a key intermediate in the synthesis of cyclopenta(cd)pyrene and CPPE, as described starting from 1,2,3,6,7,8-hexahydropyrene. 4-Pyrenylacetic acid is prepared from the c
Autor:
S R, Tannenbaum, W G, Stillwell, H, Ji, P L, Skipper, M C, Yu, R K, Ross, B E, Henderson, R J, Turesky, G A, Gross
Publikováno v:
Princess Takamatsu symposia. 23
The metabolism of the heterocyclic amines has been extensively studied in rodents and limited studies have been conducted in nonhuman primates. A study has been undertaken on the metabolism of 2-amino-3,8-dimethylimadazo[4,5-f]quinoxaline (MeIQx) in
Publikováno v:
Cancer research. 54(21)
The effect of cell replication on histone-carcinogen adducts was investigated by determining the specific adduct levels as a function of time following carcinogen treatment of human TK6 cells grown in culture. Core histones isolated from cells treate
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 3(5)
The heterocyclic aromatic amines produced by high temperature cooking of foods containing creatin(in)e and amino acids (such as beef, pork, poultry and fish) are a class of potent animal carcinogens and have been implicated indirectly in human colon
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 3(5)
The contribution of Phase II conjugation reactions to human disposition of 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline (MelQx) was investigated by analysis of urine for MelQx and its sulfamate and glucuronide metabolites. Subjects consumed pan-fri
Autor:
P L, Skipper, W G, Stillwell
Publikováno v:
Methods in enzymology. 231