Zobrazeno 1 - 10
of 143
pro vyhledávání: '"P. L. Janssen"'
Autor:
Jana V. P. Devos, Marcus L. F. Janssen, A. Miranda L. Janssen, Catharine A. Hellingman, Jasper V. Smit
Publikováno v:
Audiology Research, Vol 14, Iss 5, Pp 875-892 (2024)
Background: Limited information is available on factors that affect the burden tinnitus. The aim of this study is to investigate the association between tinnitus burden and demographic, patient-specific and tinnitus characteristics. Secondly, it was
Externí odkaz:
https://doaj.org/article/2974d3573a784291a8d8bbd80f9cc6fe
Autor:
Matthijs L. Janssen, Annemijn H. Jonkman, Myrte Wennen, Evert-Jan Wils, Henrik Endeman, Leo Heunks
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-7 (2023)
Abstract There is a need to monitor tidal volume in critically ill patients with acute respiratory failure, given its relation with adverse clinical outcome. However, quantification of tidal volume in non-intubated patients is challenging. In this pr
Externí odkaz:
https://doaj.org/article/7f8029721da64991a59de07402a02fbe
Autor:
Harry L. Janssen, Young-Suk Lim, Hyung Joon Kim, Leonard Sowah, Cheng-Hao Tseng, Carla S. Coffin, Magdy Elkhashab, Sang Hoon Ahn, Anh-Hoa Nguyen, Diana Chen, Jeffrey J. Wallin, Simon P. Fletcher, Circe McDonald, Jenny C. Yang, Anuj Gaggar, Diana M. Brainard, Scott Fung, Yoon Jun Kim, Jia-Horng Kao, Wan-Long Chuang, Anna E. Brooks, P. Rod Dunbar
Publikováno v:
JHEP Reports, Vol 6, Iss 2, Pp 100975- (2024)
Background & Aims: Novel finite therapies for chronic hepatitis B (CHB) are needed, since lifelong treatment is usually required with current available oral antivirals. This phase II study (NCT03615066) evaluated the safety, pharmacodynamics, and ant
Externí odkaz:
https://doaj.org/article/830efe33915b4c0397fd5c5452831890
Autor:
Joseph A. M. J. L. Janssen
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5488 (2024)
The worldwide incidence of prediabetes/type 2 has continued to rise the last 40 years. In the same period, the mean daily energy intake has increased, and the quality of food has significantly changed. The chronic exposure of pancreatic β-cells to c
Externí odkaz:
https://doaj.org/article/aac3c7cd97e647c9a46694aa1d482d76
Autor:
Gusta van Zwieten, Jana V. P. Devos, Sonja A. Kotz, Linda Ackermans, Pia Brinkmann, Lobke Dauven, Erwin L. J. George, A. Miranda L. Janssen, Bernd Kremer, Carsten Leue, Michael Schwartze, Yasin Temel, Jasper V. Smit, Marcus L. F. Janssen
Publikováno v:
Audiology Research, Vol 13, Iss 1, Pp 49-63 (2022)
Background: Chronic tinnitus can have an immense impact on quality of life. Despite recent treatment advances, many tinnitus patients remain refractory to them. Preclinical and clinical evidence suggests that deep brain stimulation (DBS) is a promisi
Externí odkaz:
https://doaj.org/article/8686bbd27d434d6db134acea9d62b6ac
Publikováno v:
BMC Women's Health, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background The mean incidence of ovarian metastases (OM) in patients with colorectal cancer (CRC) is 3.4%. The 5-year survival of these patients, even when operated with curative intent, is remarkably low. The lifetime risk of ovarian cancer
Externí odkaz:
https://doaj.org/article/338f0c84318f4c49916fe1a188c5fed6
Autor:
Jelle R. Miedema, Matthijs L. Janssen, Jan von der Thüsen, Henrik Endeman, Anton W. Langerak, Merel E. Hellemons, Els van Nood, Bas W. A. Peeters, Sara J. Baart, Marco W. J. Schreurs
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundIncreased titers of autoantibodies targeting the G-protein-coupled receptors angiotensin II type 1 receptor (AT1R) and endotelin-1 type A receptor (ETAR) are associated with severe coronavirus disease 2019 (COVID-19) infection. The aim of t
Externí odkaz:
https://doaj.org/article/5501f589f5ac42268f103cfaa3443a8c
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17577 (2023)
Heart failure (HF) presents a significant clinical challenge, with current treatments mainly easing symptoms without stopping disease progression. The targeting of calcium (Ca2+) regulation is emerging as a key area for innovative HF treatments that
Externí odkaz:
https://doaj.org/article/78503e0a1d8d4a1493982df352f90166
Autor:
Ning Li, Esthela Artiga, Anuradha Kalyanasundaram, Brian J. Hansen, Amy Webb, Maciej Pietrzak, Brandon Biesiadecki, Bryan Whitson, Nahush A. Mokadam, Paul M. L. Janssen, John D. Hummel, Peter J. Mohler, Halina Dobrzynski, Vadim V. Fedorov
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Heart failure (HF) is frequently accompanied with the sinoatrial node (SAN) dysfunction, which causes tachy-brady arrhythmias and increased mortality. MicroRNA (miR) alterations are associated with HF progression. However, the transcriptome
Externí odkaz:
https://doaj.org/article/d1f3400a06c3430697951538c406b0ec
Autor:
Francesca Pittino, Juliana Oliveira, Mariana De Almeida Torres, Sabine Fink, Elisabeth M. L. Janssen, Christoph Scheidegger
Publikováno v:
CHIMIA, Vol 76, Iss 11 (2022)
Cyanobacteria, also known as blue-green algae, are photosynthetic bacteria that can colonize different habitats, including extreme ones. They are of great interest to the scientific community, especially because of their ability to produce cyanotoxin
Externí odkaz:
https://doaj.org/article/c2f300643696496fbb2f64537849eb51