Zobrazeno 1 - 10
of 375
pro vyhledávání: '"P. L. Graham"'
Autor:
D. Cuda, M. Manrique, Á. Ramos, M. Marx, R. Bovo, R. Khnifes, O. Hilly, J. Belmin, G. Stripeikyte, P. L. Graham, C. J. James, P. V. Greenham, I. Mosnier
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Hearing loss impacts health-related quality of life and general well-being and was identified in a Lancet report as one of the largest potentially modifiable factors for the prevention of age-related dementia. There is a lack of r
Externí odkaz:
https://doaj.org/article/4a9c243a23ea4ef1b85284d87eb808ba
Autor:
Isabelle Mosnier, Joël Belmin, Domenico Cuda, Raquel Manrique Huarte, Mathieu Marx, Angel Ramos Macias, Riad Khnifes, Ohad Hilly, Roberto Bovo, Chris J. James, Petra L. Graham, Paula Greenham
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
BackgroundUntreated hearing loss has an effect on cognition. It is hypothesized that the additional processing required to compensate for the sensory loss affects the cognitive resources available for other tasks and that this could be mitigated by a
Externí odkaz:
https://doaj.org/article/d25c318a22aa46a58bfc272638842289
Autor:
Chadi M Saad-Roy, Sinead E Morris, Mike Boots, Rachel E Baker, Bryan L Lewis, Jeremy Farrar, Madhav V Marathe, Andrea L Graham, Simon A Levin, Caroline E Wagner, C Jessica E Metcalf, Bryan T Grenfell
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 8, p e1012211 (2024)
The SARS-CoV-2 pandemic has generated a considerable number of infections and associated morbidity and mortality across the world. Recovery from these infections, combined with the onset of large-scale vaccination, have led to rapidly-changing popula
Externí odkaz:
https://doaj.org/article/a34513b233704ad2a385f1cd24acf2f0
Autor:
Alexandra Schäfer, Lisa E. Gralinski, Sarah R. Leist, Brea K. Hampton, Michael A. Mooney, Kara L. Jensen, Rachel L. Graham, Sudhakar Agnihothram, Sophia Jeng, Steven Chamberlin, Timothy A. Bell, D. Trevor Scobey, Colton L. Linnertz, Laura A. VanBlargan, Larissa B. Thackray, Pablo Hock, Darla R. Miller, Ginger D. Shaw, Michael S. Diamond, Fernando Pardo Manuel de Villena, Shannon K. McWeeney, Mark T. Heise, Vineet D. Menachery, Martin T. Ferris, Ralph S. Baric
Publikováno v:
Virus Research, Vol 344, Iss , Pp 199357- (2024)
Coronavirus (CoV) cause considerable morbidity and mortality in humans and other mammals, as evidenced by the emergence of Severe Acute Respiratory CoV (SARS-CoV) in 2003, Middle East Respiratory CoV (MERS-CoV) in 2012, and SARS-CoV-2 in 2019. Althou
Externí odkaz:
https://doaj.org/article/b0e04c6b05a3457095b5a1d8a67680f6
Autor:
David J. Leishman, Scott H. Oppler, Laura L. Hocum Stone, Timothy D. O’Brien, Sabarinathan Ramachandran, Bradley J. Willenberg, Andrew B. Adams, Bernhard J. Hering, Melanie L. Graham
Publikováno v:
Frontiers in Transplantation, Vol 3 (2024)
IntroductionSuccessful diabetes reversal using pancreatic islet transplantation by various groups illustrates the significant achievements made in cell-based diabetes therapy. While clinically, intraportal islet delivery is almost exclusively used, i
Externí odkaz:
https://doaj.org/article/335e45c1fc714300bdfd3610c0c06ce1
Autor:
Samuel A. Einstein, Leah V. Steyn, Bradley P. Weegman, Thomas M. Suszynski, Athanassios Sambanis, Timothy D. O’Brien, Efstathios S. Avgoustiniatos, Meri T. Firpo, Melanie L. Graham, Jody Janecek, Lynn E. Eberly, Michael Garwood, Charles W. Putnam, Klearchos K. Papas
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
IntroductionSubcutaneous macroencapsulation devices circumvent disadvantages of intraportal islet therapy. However, a curative dose of islets within reasonably sized devices requires dense cell packing. We measured internal PO2 of implanted devices,
Externí odkaz:
https://doaj.org/article/4d2c40b1f118487788b0c8b74419747e
Autor:
Devaraj Basavarajappa, Vivek Gupta, Nitin Chitranshi, Roshana Vander Wall, Rashi Rajput, Kanishka Pushpitha, Samridhi Sharma, Mehdi Mirzaei, Alexander Klistorner, Stuart L Graham
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 4, Pp 840-848 (2023)
Sphingosine-1-phosphate receptor (S1PR) signaling regulates diverse pathophysiological processes in the central nervous system. The role of S1PR signaling in neurodegenerative conditions is still largely unidentified. Siponimod is a specific modulato
Externí odkaz:
https://doaj.org/article/e0828853093d47b697af5c2385f0fc1c
Autor:
Haoshen Shi, Zhuoran Yin, Yosef Koronyo, Dieu-Trang Fuchs, Julia Sheyn, Miyah R. Davis, Jered W. Wilson, Milica A. Margeta, Kristen M. Pitts, Shawn Herron, Seiko Ikezu, Tsuneya Ikezu, Stuart L. Graham, Vivek K. Gupta, Keith L. Black, Mehdi Mirzaei, Oleg Butovsky, Maya Koronyo-Hamaoui
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-22 (2022)
Abstract Single cell RNA sequencing studies identified novel neurodegeneration-associated microglial (MGnD/DAM) subtypes activated around cerebral amyloid plaques. Micro-RNA (miR)-155 of the TREM2-APOE pathway was shown to be a key transcriptional re
Externí odkaz:
https://doaj.org/article/6295f0a29d264d44a2eee4921e0f8872
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Women generally mount a stronger immune response to infections than men do, resulting in a higher impact of autoimmune diseases. Here, the authors show that pathogen transmission from mother-to-child during pregnancy drives the co-evolution of a stou
Externí odkaz:
https://doaj.org/article/797b4d89bcaf4af08774ff79cc11f2e3
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Tinnitus is a common symptom in cochlear implant (CI) recipients. There is no clear evidence of the influence of tinnitus on hearing-related quality of life (QoL) in this population. The aim of this study was to assess the relationship betwe
Externí odkaz:
https://doaj.org/article/baf268d90ee643eea34c8b21b8e2dfdf