Zobrazeno 1 - 10
of 3 463
pro vyhledávání: '"P. Kouba"'
Autor:
Bushuiev, Anton, Bushuiev, Roman, Kouba, Petr, Filkin, Anatolii, Gabrielova, Marketa, Gabriel, Michal, Sedlar, Jiri, Pluskal, Tomas, Damborsky, Jiri, Mazurenko, Stanislav, Sivic, Josef
Discovering mutations enhancing protein-protein interactions (PPIs) is critical for advancing biomedical research and developing improved therapeutics. While machine learning approaches have substantially advanced the field, they often struggle to ge
Externí odkaz:
http://arxiv.org/abs/2310.18515
Autor:
Tomáš Kovaľ, Nabajyoti Borah, Petra Sudzinová, Barbora Brezovská, Hana Šanderová, Viola Vaňková Hausnerová, Alena Křenková, Martin Hubálek, Mária Trundová, Kristýna Adámková, Jarmila Dušková, Marek Schwarz, Jana Wiedermannová, Jan Dohnálek, Libor Krásný, Tomáš Kouba
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Mycobacterial HelD is a transcription factor that recycles stalled RNAP by dissociating it from nucleic acids and, if present, from the antibiotic rifampicin. The rescued RNAP, however, must disengage from HelD to participate in subsequent r
Externí odkaz:
https://doaj.org/article/b4ae507a61d547bd9ec5f46e0019e458
Publikováno v:
Environmental Sciences Europe, Vol 36, Iss 1, Pp 1-12 (2024)
Abstract Biological invasions pose a global challenge, threatening both biodiversity and human well-being. Projections suggest that as invasions increase, the financial costs associated with management and the ecological harm they cause will also esc
Externí odkaz:
https://doaj.org/article/e7f0525dafb84e10996fc73ac29dcbdd
Autor:
Ondřej Bulvas, Zdeněk Knejzlík, Jakub Sýs, Anatolij Filimoněnko, Monika Čížková, Kamila Clarová, Dominik Rejman, Tomáš Kouba, Iva Pichová
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Allosteric regulation of inosine 5′-monophosphate dehydrogenase (IMPDH), an essential enzyme of purine metabolism, contributes to the homeostasis of adenine and guanine nucleotides. However, the precise molecular mechanism of IMPDH regulat
Externí odkaz:
https://doaj.org/article/8cabb055440b47878510600bec877241
Self-excited systems (SES) arise in numerous applications, such as fluid-structure interaction, combustion, and biochemical systems. In support of system identification and digital control of SES, this paper analyzes discrete-time Lur'e models with a
Externí odkaz:
http://arxiv.org/abs/2307.03851
Autor:
Sana Kouba, Nicolas Demaurex
Publikováno v:
Chronic Diseases and Translational Medicine, Vol 10, Iss 4, Pp 263-280 (2024)
Abstract Alterations in cellular calcium (Ca2+) signals have been causally associated with the development and progression of human cancers. Cellular Ca2+ signals are generated by channels, pumps, and exchangers that move Ca2+ ions across membranes a
Externí odkaz:
https://doaj.org/article/12e378082adb4fdab9f70b78d6768e72
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Bird sex determination is fundamental in various ecological and biological studies, although many avian species cannot be sexed visually due to their monomorphic and/or monochromatic appearance. Thus, reliable laboratory methods for sexing a
Externí odkaz:
https://doaj.org/article/3f8c3963219b4b27abd26871008e6929
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The concept of a standardized reference diet (SRD) is used in laboratory model organisms to ensure nutritional control between studies and laboratories. Although models using the genetically identical, all female parthenogenetic marbled cray
Externí odkaz:
https://doaj.org/article/803bb28dc7194703a4f24028cd3280a5
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Fatty acid accumulation was studied in the parthenogenetic all-female marbled crayfish Procambarus virginalis using six arbitrarily designed experimental feeds and related to individuals with glair glands (sexual maturity) after 100 days of
Externí odkaz:
https://doaj.org/article/4b7712499d1c4295bd96fc39aafee92b
Autor:
Sérgio M. Marques, Petr Kouba, Anthony Legrand, Jiri Sedlar, Lucas Disson, Joan Planas-Iglesias, Zainab Sanusi, Antonin Kunka, Jiri Damborsky, Tomas Pajdla, Zbynek Prokop, Stanislav Mazurenko, Josef Sivic, David Bednar
Publikováno v:
JACS Au, Vol 4, Iss 6, Pp 2228-2245 (2024)
Externí odkaz:
https://doaj.org/article/7910a03b1e3c466486a988ae2dbf68c8