Zobrazeno 1 - 10
of 658
pro vyhledávání: '"P. Kogner"'
Autor:
O. C. Bedoya-Reina, W. Li, M. Arceo, M. Plescher, P. Bullova, H. Pui, M. Kaucka, P. Kharchenko, T. Martinsson, J. Holmberg, I. Adameyko, Q. Deng, C. Larsson, C. C. Juhlin, P. Kogner, S. Schlisio
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Childhood neuroblastoma can be separated into high and low risk groups, with prognosis depending on age at diagnosis. Here, the authors show that low and high risk neuroblastoma tumours are composed of different cell types with different malignancy p
Externí odkaz:
https://doaj.org/article/2ac0672b775e4f4eafbfba1aed0015e6
Autor:
Thale K. Olsen, Jörg Otte, Shenglin Mei, Bethel Tesfai Embaie, Polina Kameneva, Huaitao Cheng, Teng Gao, Vasilios Zachariadis, Ioanna Tsea, Åsa Björklund, Emil Kryukov, Ziyi Hou, Anna Johansson, Erik Sundström, Tommy Martinsson, Susanne Fransson, Jakob Stenman, Shahrzad Shirazi Fard, John Inge Johnsen, Per Kogner, Igor Adameyko, Martin Enge, Peter V. Kharchenko, Ninib Baryawno
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Neuroblastoma (NB) is a heterogeneous embryonal malignancy and the deadliest tumor of infancy. It is a complex disease that can result in diverse clinical outcomes. In some children, tumors regress spontaneously. Others respond we
Externí odkaz:
https://doaj.org/article/1d5da37f62bb4e9c8494a94bf33d81b4
Autor:
Medha Suman, Maja Löfgren, Susanne Fransson, Jewahri Idris Yousuf, Johanna Svensson, Anna Djos, Tommy Martinsson, Per Kogner, Teresia Kling, Helena Carén
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-25 (2024)
Abstract Background Neuroblastoma (NB) is a complex disease, and the current understanding of NB biology is limited. Deregulation in genomic imprinting is a common event in malignancy. Since imprinted genes play crucial roles in early fetal growth an
Externí odkaz:
https://doaj.org/article/4d33e6752f68449d9e475c908b6d3e32
Autor:
Se Whee Sammy Park, Susanne Fransson, Fredrik Sundquist, Joachim N. Nilsson, Per Grybäck, Sandra Wessman, Jacob Strömgren, Anna Djos, Henrik Fagman, Helene Sjögren, Kleopatra Georgantzi, Nikolas Herold, Per Kogner, Dan Granberg, Mark N. Gaze, Tommy Martinsson, Kasper Karlsson, Jakob J. E. Stenman
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
In this case report, we present the treatment outcomes of the first patient enrolled in the LuDO-N trial. The patient is a 21-month-old girl diagnosed with high-risk neuroblastoma (NB) and widespread skeletal metastasis. The patient initially underwe
Externí odkaz:
https://doaj.org/article/41ba518bf7834ac3b8d9e8df52b0b021
Autor:
Ahlem Zaghmi, Erdem Aybay, Long Jiang, Mingmei Shang, Julia Steinmetz‐Späh, Fredrik Wermeling, Per Kogner, Marina Korotkova, Päivi Östling, Per‐Johan Jakobsson, Brinton Seashore‐Ludlow, Karin Larsson
Publikováno v:
Molecular Oncology, Vol 18, Iss 2, Pp 317-335 (2024)
High‐throughput drug screening enables the discovery of new anticancer drugs. Although monolayer cell cultures are commonly used for screening, their limited complexity and translational efficiency require alternative models. Three‐dimensional ce
Externí odkaz:
https://doaj.org/article/4a29d39e06f844be8b5afb223e6cda70
Akademický článek
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Autor:
Teresita Díaz de Ståhl, Alia Shamikh, Markus Mayrhofer, Szilvester Juhos, Elisa Basmaci, Gabriela Prochazka, Maxime Garcia, Praveen Raj Somarajan, Katarzyna Zielinska-Chomej, Christopher Illies, Ingrid Øra, Peter Siesjö, Per-Erik Sandström, Jakob Stenman, Magnus Sabel, Bengt Gustavsson, Per Kogner, Susan Pfeifer, Gustaf Ljungman, Johanna Sandgren, Monica Nistér
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract The Swedish Childhood Tumor Biobank (BTB) is a nonprofit national infrastructure for collecting tissue samples and genomic data from pediatric patients diagnosed with central nervous system (CNS) and other solid tumors. The BTB is built on a
Externí odkaz:
https://doaj.org/article/7240e3c4477b412ab92cab9a38e14c6c
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Treatment-related skeletal complications are common in childhood cancer patients and survivors. Venetoclax is a BCL-2 inhibitor that has shown efficacy in hematological malignancies in adults and is being investigated in pediatric cancer cli
Externí odkaz:
https://doaj.org/article/e983c9fc1e2f4c2a84412b0c7efcf860
Autor:
Eva Proestler, Julia Donzelli, Sheila Nevermann, Kai Breitwieser, Leon F. Koch, Tatjana Best, Maria Fauth, Malin Wickström, Patrick N. Harter, Per Kogner, Grégory Lavieu, Karin Larsson, Meike J. Saul
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Neuroblastoma is the most common extracranial solid tumor in childhood and arises from neural crest cells of the developing sympathetic nervous system. Prostaglandin E2 (PGE2) has been identified as a key pro-inflammatory mediator of the tumor microe
Externí odkaz:
https://doaj.org/article/dac53945b2fc4e109c405ee632c4379e
Akademický článek
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