Zobrazeno 1 - 10
of 94
pro vyhledávání: '"P. Kalita-de Croft"'
Autor:
Vaibhavi Joshi, Andrew Stacey, Yufan Feng, Priyakshi Kalita‐de Croft, Pascal HG Duijf, Peter T Simpson, Sunil R Lakhani, Amy E McCart Reed
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 2, Pp n/a-n/a (2024)
Abstract Brain metastases are secondary brain tumours characterised by their aggressive nature and poor prognosis. Breast cancer is one of the most common primary tumours in women to spread to the brain. A lack of biomarkers predicting likely spread
Externí odkaz:
https://doaj.org/article/2bd621ffce7f468c8b7dd6bbf721be3c
Autor:
Duy Pham, Xiao Tan, Brad Balderson, Jun Xu, Laura F. Grice, Sohye Yoon, Emily F. Willis, Minh Tran, Pui Yeng Lam, Arti Raghubar, Priyakshi Kalita-de Croft, Sunil Lakhani, Jana Vukovic, Marc J. Ruitenberg, Quan H. Nguyen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-25 (2023)
Abstract Spatial transcriptomics (ST) technologies generate multiple data types from biological samples, namely gene expression, physical distance between data points, and/or tissue morphology. Here we developed three computational-statistical algori
Externí odkaz:
https://doaj.org/article/90386dc9c14b4450ad2ce44635d342ec
Autor:
Jodi M. Saunus, Xavier M. De Luca, Korinne Northwood, Ashwini Raghavendra, Alexander Hasson, Amy E. McCart Reed, Malcolm Lim, Samir Lal, A. Cristina Vargas, Jamie R. Kutasovic, Andrew J. Dalley, Mariska Miranda, Emarene Kalaw, Priyakshi Kalita-de Croft, Irma Gresshoff, Fares Al-Ejeh, Julia M. W. Gee, Chris Ormandy, Kum Kum Khanna, Jonathan Beesley, Georgia Chenevix-Trench, Andrew R. Green, Emad A. Rakha, Ian O. Ellis, Dan V. Nicolau, Peter T. Simpson, Sunil R. Lakhani
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Intratumoral heterogeneity is caused by genomic instability and phenotypic plasticity, but how these features co-evolve remains unclear. SOX10 is a neural crest stem cell (NCSC) specifier and candidate mediator of phenotypic plasticity in ca
Externí odkaz:
https://doaj.org/article/8a3be3a876b24ea3b406d64dc3b52fe6
Akademický článek
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Autor:
Soumyalekshmi Nair, Dominic Guanzon, Nanthini Jayabalan, Andrew Lai, Katherin Scholz-Romero, Priyakshi Kalita de Croft, Valeska Ormazabal, Carlos Palma, Emilio Diaz, Elizabeth A. McCarthy, Alexis Shub, Jezid Miranda, Eduard Gratacós, Fátima Crispi, Gregory Duncombe, Martha Lappas, H. David McIntyre, Gregory Rice, Carlos Salomon
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Gestational diabetes mellitus (GDM) is a serious public health issue affecting 9–15% of all pregnancies worldwide. Recently, it has been suggested that extracellular vesicles (EVs) play a role throughout gestation, including med
Externí odkaz:
https://doaj.org/article/459eca6bdc89459c879879f07f4b0b45
Akademický článek
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Autor:
Julien Clegg, Maria K. Koch, Erik W. Thompson, Larisa M. Haupt, Priyakshi Kalita-de Croft, Laura J. Bray
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The extracellular matrix (ECM) provides cues to direct mammogenesis, tumourigenesis and metastatic processes. Over the past several decades, two-dimensional (2D) culture models have been invaluable in furthering our understanding of the tumor microen
Externí odkaz:
https://doaj.org/article/3c031b4f50f2466d9f88b0a66bb0ae8e
Autor:
Priyakshi Kalita-de Croft, Malcolm Lim, Haarika Chittoory, Xavier M. de Luca, Jamie R. Kutasovic, Bryan W. Day, Fares Al-Ejeh, Peter T. Simpson, Amy E. McCart Reed, Sunil R. Lakhani, Jodi M. Saunus
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Human epidermal growth factor receptor-4 (HER4) and yes-associated protein-1 (YAP) are candidate therapeutic targets in oncology. YAP’s transcriptional coactivation function is modulated by the HER4 intracellular domain (HER4-ICD) in vi
Externí odkaz:
https://doaj.org/article/e545a5481be646f1a10e52cfc1f50775
Publikováno v:
Diseases, Vol 10, Iss 1, p 11 (2022)
Primary malignancies of the lung, skin (melanoma), and breast have higher propensity for metastatic spread to the brain. Advances in molecular tumour profiling have aided the development of targeted therapies, stereotactic radiotherapy, and immunothe
Externí odkaz:
https://doaj.org/article/ea363dfefbff4a538549380c52c77933
Publikováno v:
Cells, Vol 10, Iss 9, p 2272 (2021)
Ovarian cancer (OC) is one of the most diagnosed gynecological cancers in women. Due to the lack of effective early stage screening, women are more often diagnosed at an advanced stage; therefore, it is associated with poor patient outcomes. There ar
Externí odkaz:
https://doaj.org/article/51dad162fa7844a48c2586f9b43046bf