Zobrazeno 1 - 4
of 4
pro vyhledávání: '"P. K. S. Siegl"'
Autor:
T. W. Schorn, H. H. Thorpe, J. D. Frank, P. K. S. Siegl, P. B. Bunting, Raymond E. Gibson, M. E. Cartwright
Publikováno v:
American Journal of Physiology-Renal Physiology. 261:F512-F518
The angiotensin II (ANG II) receptor has recently been shown to exhibit subtypes with respect to antagonist binding. Of particular interest are the potent nonpeptide antagonists, DUP 753 and PD 121981, which exhibit selectivity for the subtype 1 (AT1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2358dd153fe95fd65a103e9c8795f68e
https://doi.org/10.1152/ajprenal.1991.261.3.f512
https://doi.org/10.1152/ajprenal.1991.261.3.f512
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 24(6)
Endothelin-1 (ET-1) has been found to be one of the most potent vasoconstrictive peptides known, and is therefore considered to be an important factor in diseases such as hypertension, heart failure, pulmonary hypertension, renal diseases, etc. Thus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b48c98bc7d90c70bb1bced240a477a
https://pubmed.ncbi.nlm.nih.gov/12224443
https://pubmed.ncbi.nlm.nih.gov/12224443
Autor:
S. E. de Laszlo, B. L. Bush, J. J. Doyle, W. J. Greenlee, D. G. Hangauer, T. A. Halgren, R. J. Lynch, T. W. Schorn, P. K. S. Siegl
Publikováno v:
Peptides ISBN: 9789401090629
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a0f0863533e05105b04566231c3369a
https://doi.org/10.1007/978-94-010-9060-5_142
https://doi.org/10.1007/978-94-010-9060-5_142
The negative inotropic potency of compound D 600 in rat, guinea pig, and rabbit cardiac preparations
Autor:
J. H. McNeill, P. K. S. Siegl
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 58:1406-1411
The negative inotropic effect of compound D was examined in isolated cardiac preparations from several species. Based upon calculated pD2 values, D 600 was most potent in rabbit papillary muscles (pD2 = 7.54), similar or less potent in guinea pig lef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b076afbf5935505ead6d38abfd1ca766
https://doi.org/10.1139/y80-213
https://doi.org/10.1139/y80-213