Zobrazeno 1 - 10
of 30
pro vyhledávání: '"P. K. Rogan"'
Publikováno v:
Molecular Cytogenetics, Vol 14, Iss 1, Pp 1-17 (2021)
Abstract Background During mitosis, chromatin engages in a dynamic cycle of condensation and decondensation. Condensation into distinct units to ensure high fidelity segregation is followed by rapid and reproducible decondensation to produce function
Externí odkaz:
https://doaj.org/article/6a0d7606994246e9bee5884f77af4ad6
Publikováno v:
F1000Research, Vol 10 (2022)
Introduction: This study aimed to produce community-level geo-spatial mapping of confirmed COVID-19 cases in Ontario Canada in near real-time to support decision-making. This was accomplished by area-to-area geostatistical analysis, space-time integr
Externí odkaz:
https://doaj.org/article/9c835f2d16194e11b7add5dfd6ac8762
Autor:
Peter K. Rogan, Eliseos J. Mucaki, Ben C. Shirley, Yanxin Li, Ruth C. Wilkins, Farrah Norton, Olga Sevriukova, Ngoc-Duy Pham, Ed Waller, Joan H. M. Knoll
Publikováno v:
Radiation, Vol 1, Iss 2, Pp 79-94 (2021)
The dicentric chromosome (DC) assay accurately quantifies exposure to radiation; however, manual and semi-automated assignment of DCs has limited its use for a potential large-scale radiation incident. The Automated Dicentric Chromosome Identifier an
Externí odkaz:
https://doaj.org/article/caffb16babfa41bda8a73d3e0a6c6f70
Publikováno v:
F1000Research, Vol 10 (2021)
Introduction: This study aimed to produce community-level geo-spatial mapping of confirmed COVID-19 cases in Ontario Canada in near real-time to support decision-making. This was accomplished by area-to-area geostatistical analysis, space-time integr
Externí odkaz:
https://doaj.org/article/5e9a16819f3947a08cff4f73b10a565f
Publikováno v:
F1000Research, Vol 9 (2021)
Background: Certain riboviruses can cause severe pulmonary complications leading to death in some infected patients. We propose that DNA damage induced-apoptosis accelerates viral release, triggered by depletion of host RNA binding proteins (RBPs) fr
Externí odkaz:
https://doaj.org/article/97dfc02da36b49a7a64366301066cab2
Publikováno v:
F1000Research, Vol 9 (2020)
Background: Certain riboviruses can cause severe pulmonary complications leading to death in some infected patients. We propose that DNA damage induced-apoptosis accelerates viral release, triggered by depletion of host RNA binding proteins (RBPs) fr
Externí odkaz:
https://doaj.org/article/52ac6d3c52254b0a94ef4bcd4a8d0bda
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Splice isoform structure and abundance can be affected by either noncoding or masquerading coding variants that alter the structure or abundance of transcripts. When these variants are common in the population, these nonconstitutive transcripts are s
Externí odkaz:
https://doaj.org/article/dc66a3f41c4b4fd3bc9741e53202859c
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232008 (2020)
BackgroundAccurate radiation dose estimates are critical for determining eligibility for therapies by timely triaging of exposed individuals after large-scale radiation events. However, the universal assessment of a large population subjected to a nu
Externí odkaz:
https://doaj.org/article/c013da4558ac4b58b0de238eb7970933
Publikováno v:
F1000Research, Vol 7 (2019)
We present a major public resource of mRNA splicing mutations validated according to multiple lines of evidence of abnormal gene expression. Likely mutations present in all tumor types reported in the Cancer Genome Atlas (TCGA) and the International
Externí odkaz:
https://doaj.org/article/276d14dba3ff461abb47fffea708f7d7
Autor:
Ruipeng Lu, Peter K. Rogan
Publikováno v:
F1000Research, Vol 7 (2019)
Background: The distribution and composition of cis-regulatory modules composed of transcription factor (TF) binding site (TFBS) clusters in promoters substantially determine gene expression patterns and TF targets. TF knockdown experiments have reve
Externí odkaz:
https://doaj.org/article/126d64b0a1154e88af6f6eb2374015e1