Zobrazeno 1 - 10
of 76
pro vyhledávání: '"P. K. Grant"'
Autor:
Péter Ábrányi-Balogh, Dávid Bajusz, Zoltán Orgován, Aaron B. Keeley, László Petri, Nikolett Péczka, Tibor Viktor Szalai, Gyula Pálfy, Márton Gadanecz, Emma K. Grant, Tímea Imre, Tamás Takács, Ivan Ranđelović, Marcell Baranyi, András Marton, Gitta Schlosser, Qirat F. Ashraf, Elvin D. de Araujo, Tamás Karancsi, László Buday, József Tóvári, András Perczel, Jacob T. Bush, György M. Keserű
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Fragment screening is a popular strategy of generating viable chemical starting points especially for challenging targets. Although fragments provide a better coverage of chemical space and they have typically higher chance of binding, their
Externí odkaz:
https://doaj.org/article/0a79f05dcd144d4ba343eaa1f806db99
Autor:
Daniel P. Windred, Clare Anderson, Katherine J. Jeppe, Suzanne Ftouni, Leilah K. Grant, Brunda Nijagal, Shantha M. W. Rajaratnam, Malcolm McConville, Dedreia Tull, Steven W. Lockley, Sean W. Cain, Andrew J. K. Phillips
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Robust circadian rhythms are essential for optimal health. The central circadian clock controls temperature rhythms, which are known to organize the timing of peripheral circadian rhythms in rodents. In humans, however, it is unknown whether
Externí odkaz:
https://doaj.org/article/ce80eed627b4403e834c2bde07e9dbe3
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 2, Pp 100493- (2024)
Dietary supplements augment the nutritional value of everyday food intake and originate from the historical practices of ancient Egyptian (Ebers papyrus), Chinese (Pen Ts’ao by Shen Nung), Indian (Ayurveda), Greek (Hippocrates), and Arabic herbalis
Externí odkaz:
https://doaj.org/article/0a748dd35d674fd8b27ed314cc061448
Autor:
Brian G. Murphy, Diego Castillo, N E Neely, Amir Kol, Terza Brostoff, Chris K. Grant, Krystle L. Reagan
Publikováno v:
Viruses, Vol 16, Iss 3, p 462 (2024)
Feline infectious peritonitis (FIP) is a multisystemic, generally lethal immuno-inflammatory disease of domestic cats caused by an infection with a genetic variant of feline coronavirus, referred to as the FIP virus (FIPV). We leveraged data from fou
Externí odkaz:
https://doaj.org/article/bb02d15788dd49f1a7821efe0ada804d
Autor:
Qianhui Dou, Aaron K. Grant, Cody Callahan, Patricia Coutinho de Souza, David Mwin, Adam L. Booth, Imad Nasser, Marwan Moussa, Muneeb Ahmed, Leo L. Tsai
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 1, Pp 61-75 (2023)
Background & Aims: Metabolic reprogramming, in particular, glycolytic regulation, supports abnormal survival and growth of hepatocellular carcinoma (HCC) and could serve as a therapeutic target. In this study, we sought to identify glycolytic regulat
Externí odkaz:
https://doaj.org/article/621220d3d4204af9be15d9cace9d473e
Autor:
R. L. Bromley, M. Bickle Graz, M. Bluett-Duncan, C. Chambers, P. Damkier, K. Dietrich, H. Dolk, K. Grant, S. Mattson, K. J. Meador, H. Nordeng, T. F. Oberlander, A. Ornoy, A. Revet, J. Richardson, J. Rovet, L. Schuler-Faccini, E. Smearman, V. Simms, C. Vorhees, K. Wide, A. Wood, L. Yates, E. Ystrom, T. A. Supraja, J. Adams
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Exposure in utero to certain medications can disrupt processes of fetal development, including brain development, leading to a continuum of neurodevelopmental difficulties. Recognizing the deficiency of neurodevelopmental investigations w
Externí odkaz:
https://doaj.org/article/f05115b3389b428aaedd4ceccad838ab
Autor:
Kate M. Buckeridge, Kelly E. Mason, Nick Ostle, Niall P. McNamara, Helen K. Grant, Jeanette Whitaker
Publikováno v:
Communications Earth & Environment, Vol 3, Iss 1, Pp 1-10 (2022)
Different mineralization rates between plant litter and microbial necromass do not necessarily imply differences in carbon persistence, and necromass carbon is less persistent than nitrogen, according to inoculation experiments with grassland soils u
Externí odkaz:
https://doaj.org/article/18520e71a09d4531898548600655d3cd
Autor:
C. T. Bolton, E. Gray, W. Kuhnt, A. E. Holbourn, J. Lübbers, K. Grant, K. Tachikawa, G. Marino, E. J. Rohling, A.-C. Sarr, N. Andersen
Publikováno v:
Climate of the Past, Vol 18, Pp 713-738 (2022)
In the modern northern Indian Ocean, biological productivity is intimately linked to near-surface oceanographic dynamics forced by the South Asian, or Indian, monsoon. In the late Pleistocene, this strong seasonal signal is transferred to the sedimen
Externí odkaz:
https://doaj.org/article/07ddf86a8b374f04a3bb3177edf84c47
Autor:
Brianne A. Kent, Shadab A. Rahman, Melissa A. St. Hilaire, Leilah K. Grant, Melanie Rüger, Charles A. Czeisler, Steven W. Lockley
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)
A key property of circadian rhythms is that they can be reset in response to environmental time cues; this response is described by a Phase Response Curve (PRC). Here the authors describe PRCs for resetting circadian rhythms in lipids and hepatic pro
Externí odkaz:
https://doaj.org/article/27fa74429d6e4c85a872cc758c6f7862
Autor:
Frederick K. Grant, Rose Wanjala, Jan Low, Carol Levin, Donald C. Cole, Haile S. Okuku, Robert Ackatia-Armah, Amy W. Girard
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
BackgroundInfection is associated with impaired nutritional status, especially for infants younger than 5 years.ObjectivesWe assessed the impact of infection indicated by both acute phase proteins (APP), C-reactive protein (CRP), and α-1-acid-glycop
Externí odkaz:
https://doaj.org/article/d03df1f436264574a642871e358fc85f