Zobrazeno 1 - 10
of 17
pro vyhledávání: '"P. K. Challa"'
Autor:
Z. Parsouzi, S. M. Shamid, V. Borshch, P. K. Challa, A. R. Baldwin, M. G. Tamba, C. Welch, G. H. Mehl, J. T. Gleeson, A. Jakli, O. D. Lavrentovich, D. W. Allender, J. V. Selinger, S. Sprunt
Publikováno v:
Physical Review X, Vol 6, Iss 2, p 021041 (2016)
We report a dynamic light-scattering study of the fluctuation modes in a thermotropic liquid crystalline mixture of monomer and dimer compounds that exhibits the twist-bend nematic (N_{TB}) phase. The results reveal a spectrum of overdamped fluctuati
Externí odkaz:
https://doaj.org/article/19bc4bc7cf854774bd75fc01e37d2d59
Autor:
Natalie R. Forte, Virginia N. Veasey, Bethany J. Christie, Amira Carter, Marli A. Hanks, Alan Holderfield, Taylor Houston, Anil K. Challa, Ashley N. Turner
Publikováno v:
Journal of Microbiology & Biology Education, Vol 24, Iss 3 (2023)
ABSTRACTGenetic analysis in model systems using bioinformatic approaches provides a rich context for a concrete and conceptual understanding of gene structure and function. With the intent to engage students in research and explore disease biology ut
Externí odkaz:
https://doaj.org/article/5e10066d625c43a8bb34a950defbac26
Autor:
Jiangfei Chen, Kunal Baxi, Amanda E Lipsitt, Nicole Rae Hensch, Long Wang, Prethish Sreenivas, Paulomi Modi, Xiang Ru Zhao, Antoine Baudin, Daniel G Robledo, Abhik Bandyopadhyay, Aaron Sugalski, Anil K Challa, Dias Kurmashev, Andrea R Gilbert, Gail E Tomlinson, Peter Houghton, Yidong Chen, Madeline N Hayes, Eleanor Y Chen, David S Libich, Myron S Ignatius
Publikováno v:
eLife, Vol 12 (2023)
In embryonal rhabdomyosarcoma (ERMS) and generally in sarcomas, the role of wild-type and loss- or gain-of-function TP53 mutations remains largely undefined. Eliminating mutant or restoring wild-type p53 is challenging; nevertheless, understanding p5
Externí odkaz:
https://doaj.org/article/869c09202a0d4108bb57d631b09af023
Autor:
Naveen K. Challa
Publikováno v:
African Vision and Eye Health, Vol 81, Iss 1, Pp e1-e6 (2022)
Background: Amblyopia is the leading cause of visual impairment in children and as such poses a public health problem. Prevalence studies are required to determine the magnitude of visual impairment because of amblyopia. Although there are studies th
Externí odkaz:
https://doaj.org/article/a0b0fec1ee854070a06d5f00a0a9c517
Autor:
Haifa Alsharif, Mary N. Latimer, Katherine C. Perez, Justin Alexander, Md Mostafizur Rahman, Anil K. Challa, Jeong-A. Kim, Sasanka Ramanadham, Martin Young, Sushant Bhatnagar
Publikováno v:
Metabolites, Vol 13, Iss 6, p 711 (2023)
Effective energy expenditure is critical for maintaining body weight (BW). However, underlying mechanisms contributing to increased BW remain unknown. We characterized the role of brain angiogenesis inhibitor-3 (BAI3/ADGRB3), an adhesion G-protein co
Externí odkaz:
https://doaj.org/article/6db45d1f199a4eb3b7390d521cd46ac2
Autor:
Gobinath Shanmugam, Anil K. Challa, Asokan Devarajan, Baskaran Athmanathan, Silvio H. Litovsky, Prasanna Krishnamurthy, Christopher J. Davidson, Namakkal Soorappan Rajasekaran
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Although exercise derived activation of Nrf2 signaling augments myocardial antioxidant signaling, the molecular mechanisms underlying the benefits of moderate exercise training (MET) in the heart remain elusive. Here we hypothesized that exercise tra
Externí odkaz:
https://doaj.org/article/b7425631e0854972ae1c0e78b74a584d
Autor:
Laura J. Lambert, Anil K. Challa, Aidi Niu, Lihua Zhou, Janusz Tucholski, Maria S. Johnson, Tim R. Nagy, Alan W. Eberhardt, Patrick N. Estep, Robert A. Kesterson, Jayleen M. Grams
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 10, Pp 1169-1179 (2016)
Osteocalcin, also known as bone γ-carboxyglutamate protein (Bglap), is expressed by osteoblasts and is commonly used as a clinical marker of bone turnover. A mouse model of osteocalcin deficiency has implicated osteocalcin as a mediator of changes t
Externí odkaz:
https://doaj.org/article/4416ba08da51475b9e8b9c3f546ec6a0
Autor:
Wesley R Lewis, Erik B Malarkey, Douglas Tritschler, Raqual Bower, Raymond C Pasek, Jonathan D Porath, Susan E Birket, Sophie Saunier, Corinne Antignac, Michael R Knowles, Margaret W Leigh, Maimoona A Zariwala, Anil K Challa, Robert A Kesterson, Steven M Rowe, Iain A Drummond, John M Parant, Friedhelm Hildebrandt, Mary E Porter, Bradley K Yoder, Nicolas F Berbari
Publikováno v:
PLoS Genetics, Vol 12, Iss 7, p e1006220 (2016)
Ciliopathies are genetic disorders arising from dysfunction of microtubule-based cellular appendages called cilia. Different cilia types possess distinct stereotypic microtubule doublet arrangements with non-motile or 'primary' cilia having a 9+0 and
Externí odkaz:
https://doaj.org/article/7c98f36db5424abc93f80eefd82caaec
Autor:
Anil K Challa, Evan R Boitet, Ashley N Turner, Larry W Johnson, Daniel Kennedy, Ethan R Downs, Katherine M Hymel, Alecia K Gross, Robert A Kesterson
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155812 (2016)
Tyrosinase is a key enzyme in melanin biosynthesis. Mutations in the gene encoding tyrosinase (Tyr) cause oculocutaneous albinism (OCA1) in humans. Alleles of the Tyr gene have been useful in studying pigment biology and coat color formation. Over 10
Externí odkaz:
https://doaj.org/article/95612f7154c0442c904d4ddc71281093
