Zobrazeno 1 - 10
of 47
pro vyhledávání: '"P. K. Andrews"'
Autor:
Robert M. Cox, Josef D. Wolf, Nicole A. Lieberman, Carolin M. Lieber, Hae-Ji Kang, Zachary M. Sticher, Jeong-Joong Yoon, Meghan K. Andrews, Mugunthan Govindarajan, Rebecca E. Krueger, Elizabeth B. Sobolik, Michael G. Natchus, Andrew T. Gewirtz, Rik L. deSwart, Alexander A. Kolykhalov, Khan Hekmatyar, Kaori Sakamoto, Alexander L. Greninger, Richard K. Plemper
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Measles cases have surged pre-COVID-19 and the pandemic has aggravated the problem. Most measles-associated morbidity and mortality arises from destruction of pre-existing immune memory by measles virus (MeV), a paramyxovirus of the morbilli
Externí odkaz:
https://doaj.org/article/c318e8440b28489e92886789df7a2812
Publikováno v:
Food Chemistry Advances, Vol 4, Iss , Pp 100694- (2024)
The study investigates the elemental composition and fungal contamination of commonly utilized spices and herbs, namely Turmeric, Cloves, Black pepper, Latency/cumin, Ring/legume, Cinnamon, Coriander, Ginger, Indian saffron, Fenugreek, Fennel flower,
Externí odkaz:
https://doaj.org/article/f72c8704939f494ca7ae8801320e3e07
Autor:
Robert M. Cox, Carolin M. Lieber, Josef D. Wolf, Amirhossein Karimi, Nicole A. P. Lieberman, Zachary M. Sticher, Pavitra Roychoudhury, Meghan K. Andrews, Rebecca E. Krueger, Michael G. Natchus, George R. Painter, Alexander A. Kolykhalov, Alexander L. Greninger, Richard K. Plemper
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Therapeutic options against SARS-CoV-2 are underutilized. Two oral drugs, molnupiravir and paxlovid (nirmatrelvir/ritonavir), have received emergency use authorization. Initial trials suggested greater efficacy of paxlovid, but recent studie
Externí odkaz:
https://doaj.org/article/61d1e30d9f164794bdecb43d97a77a87
Autor:
Yangyang Ding, Xiang Gui, Xiang Chu, Yueyue Sun, Sixuan Zhang, Huan Tong, Wen Ju, Yue Li, Zengtian Sun, Mengdi Xu, Zhenyu Li, Robert K. Andrews, Elizabeth E. Gardiner, Lingyu Zeng, Kailin Xu, Jianlin Qiao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Human MutT Homolog 1 (MTH1) is a nucleotide pool sanitization enzyme that hydrolyzes oxidized nucleotides to prevent their mis-incorporation into DNA under oxidative stress. Expression and functional roles of MTH1 in platelets are not known.
Externí odkaz:
https://doaj.org/article/c6a5b3d2352342c1b144fc7df9711183
Autor:
Teresa Bennett, Irene Drmic, Julie Gross, Marc Jambon, Melissa Kimber, Anat Zaidman-Zait, K. Andrews, Julia Frei, E. Duku, Stelios Georgiades, Andrea Gonzalez, Magdalena Janus, E. Lipman, Paulo Pires, Heather Prime, Caroline Roncadin, Mackenzie Salt, Rebecca Shine
Publikováno v:
Frontiers in Public Health, Vol 11 (2024)
IntroductionPrevalence rates of emotional and behavior problems (EBP) in autistic children and youth are high (40–70%), and often cause severe and chronic impairment. Furthermore, autistic children are also more likely to experience family “socia
Externí odkaz:
https://doaj.org/article/d5b989874b9e49cd995bc8873ff66e6a
Autor:
Christine Shu Mei Lee, Amandeep Kaur, Samantha J. Montague, Sarah M. Hicks, Robert K. Andrews, Elizabeth E. Gardiner
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
AbstractPlatelet-specific collagen receptor glycoprotein (GP)VI is stable on the surface of circulating platelets but undergoes ectodomain cleavage on activated platelets. Activation-dependent GPVI metalloproteolysis is primarily mediated by A Disint
Externí odkaz:
https://doaj.org/article/77429db278d34f55a26c65f85a851f2d
Publikováno v:
Platelets, Vol 32, Iss 1, Pp 47-52 (2021)
The spleen, in addition to its role in immunity, plays key roles in erythrocyte maintenance and platelet sequestration. Loss of the spleen via splenectomy occurs in approximately 6.4 to 7.1 per 100 000 people per year globally, commonly as a life-sav
Externí odkaz:
https://doaj.org/article/26a810a4101f488987730abd87a8d37c
Autor:
Chiara Pallini, Jeremy A. Pike, Christopher O’Shea, Robert K. Andrews, Elizabeth E. Gardiner, Steve P. Watson, Natalie S. Poulter
Publikováno v:
Platelets, Vol 32, Iss 1, Pp 59-73 (2021)
Collagen, the most thrombogenic constituent of blood vessel walls, activates platelets through glycoprotein VI (GPVI). In suspension, following platelet activation by collagen, GPVI is cleaved by A Disintegrin And Metalloproteinase (ADAM)10 and ADAM1
Externí odkaz:
https://doaj.org/article/5e7b1596d96d4c4aadc66a0f0873e18a
Autor:
Jianlin Qiao, Eimear Dunne, Bruce Wines, Dermot Kenny, Geraldine M. McCarthy, P. Mark Hogarth, Kailin Xu, Robert K. Andrews, Elizabeth E. Gardiner
Publikováno v:
Platelets, Vol 31, Iss 3, Pp 392-398 (2020)
Soluble forms of the low-affinity immunoglobulin receptor FcγRIIa (sFcγRIIa) lacking the cytoplasmic tail have been reported in plasma however the mechanism and functional consequences are unknown. This study aimed to evaluate mechanisms of FcγRII
Externí odkaz:
https://doaj.org/article/6fa5e942acd14a519c713e014150a62a
Autor:
Bruce D. Wines, Halina M. Trist, Sandra Esparon, Rachael E. Impey, Graham A. Mackay, Robert K. Andrews, Tatiana P. Soares da Costa, Geoffrey A. Pietersz, Ross I. Baker, P. Mark Hogarth
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
FcγR activity underpins the role of antibodies in both protective immunity and auto-immunity and importantly, the therapeutic activity of many monoclonal antibody therapies. Some monoclonal anti-FcγR antibodies activate their receptors, but the pro
Externí odkaz:
https://doaj.org/article/c9b14b59d6114647912e69dcf8f997d5