Zobrazeno 1 - 10
of 259
pro vyhledávání: '"P. Köpf-Maier"'
Autor:
M. Flug, P. Köpf-Maier
Publikováno v:
Cells Tissues Organs. 152:69-84
During the development of invasive cancer, carcinoma cells have to penetrate the extracellular matrix including the basement membrane (BM). This is a usually continuous layer composed of a dense meshwork of collagens, glycoproteins and proteoglycans.
Autor:
S.K. Mühlhausen, P. Köpf-Maier
Publikováno v:
Chemico-Biological Interactions. 82:295-316
The influence of the antitumor drug cis-diamminedichloroplatinum(II) ('cisplatin') upon the structural pattern of the main cytoskeletal components, i.e. microtubules, intermediate filaments and microfilaments, was investigated in squamous carcinoma c
Autor:
Bernd Zimmermann, P. Köpf-Maier
Publikováno v:
Cell and Tissue Research. 264:563-576
In the present study we describe a new method to cultivate human tumors, which allows organoid differentiation under in vitro conditions. Diverse tumors of different origin and various histopathology which had been heterotransplanted to athymic mice
Publikováno v:
British Journal of Cancer
The changes in the phosphorus metabolism of a xenografted hypopharynx carcinoma (Hyp 1), sensitive to cisplatin (CDDP), were compared to those occurring in two sublines of the tumour, characterised by moderate or high resistance to CDDP (Hyp 1/H and
Autor:
P. Köpf-Maier
Publikováno v:
Cells Tissues Organs. 139:164-172
In the present study, the distribution of phosphorus was analyzed within lysosomes of hepatocytes, Kupffer cells and mast cells in untreated liver tissue of mice by the use of electron-spectroscopic imaging, a new electron-microscopical method which
Autor:
P, Köpf-Maier
Publikováno v:
Anticancer research. 19(1A)
Titanocene dichloride [(C5H5)2TiCl2] is a new-developed organometallic antitumor agent which is currently being investigated in clinical trials of phases I and II. In the present study, it was tested for antitumor activity in human renal tumors eithe
Autor:
P, Köpf-Maier
Publikováno v:
In vivo (Athens, Greece). 12(3)
Treosulfan (L-threitol-1,4-bismethanesulfonate, Ovastat) was tested on human renal tumor cells growing as xenografts in athymic nude mice and as monolayers in vitro, in comparison with clinically used cytostatic drugs (in vivo, cyclophosphamide, vinb
Autor:
M, Flug, P, Köpf-Maier
Publikováno v:
Acta anatomica. 152(2)
During the development of invasive cancer, carcinoma cells have to penetrate the extracellular matrix including the basement membrane (BM). This is a usually continuous layer composed of a dense meshwork of collagens, glycoproteins and proteoglycans.