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pro vyhledávání: '"P. Jonathan Phillips"'
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 11, Iss 10 (2024)
Background Paget’s disease of bone is characterised by focal abnormalities of bone turnover resulting in various complications. It often presents at an advanced stage with irreversible bone damage. At this point, the symptomatic benefits of treatme
Externí odkaz:
https://doaj.org/article/584624e4ffa648b9bbedb288551cc042
Autor:
Isaac J. Handley-Miner, Michael Pope, Richard Kenneth Atkins, S. Mo Jones-Jang, Daniel J. McKaughan, Jonathan Phillips, Liane Young
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The concept of truth is at the core of science, journalism, law, and many other pillars of modern society. Yet, given the imprecision of natural language, deciding what information should count as true is no easy task, even with access to th
Externí odkaz:
https://doaj.org/article/cc88a71f08474a81b944384757541ec4
Publikováno v:
Stress, Vol 25, Iss 1, Pp 331-336 (2022)
Adolescent obesity augments and impedes the treatment of chronic pain. This is associated with increased systemic inflammation and is more prominent in females. In addition, pain and obesity each independently affect the hypothalamic-pituitary-adrena
Externí odkaz:
https://doaj.org/article/3a3c16a149ce4370b83545218623e4b3
Autor:
Martin Divoky, Jonathan Phillips, Jan Pilar, Martin Hanus, Petr Navratil, Ondrej Denk, Tomas Paliesek, Patricie Severova, Danielle Clarke, Martin Smrz, Thomas Butcher, Chris Edwards, John Collier, Tomas Mocek
Publikováno v:
High Power Laser Science and Engineering, Vol 11 (2023)
We report on frequency doubling of high-energy, high repetition rate ns pulses from a cryogenically gas cooled multi-slab ytterbium-doped yttrium aluminum garnet laser system, Bivoj/DiPOLE, using a type-I phase matched lithium triborate crystal. We a
Externí odkaz:
https://doaj.org/article/7025b2ffe30149b4a814ca8b8b6e7bc7
Autor:
Peter Kosa, Ruturaj Masvekar, Mika Komori, Jonathan Phillips, Vighnesh Ramesh, Mihael Varosanec, Mary Sandford, Bibiana Bielekova
Publikováno v:
JCI Insight, Vol 7, Iss 15 (2022)
BACKGROUND Serum neurofilament light chain (sNFL) is becoming an important biomarker of neuro-axonal injury. Though sNFL correlates with CSF NFL (cNFL), 40% to 60% of variance remains unexplained. We aimed to mathematically adjust sNFL to strengthen
Externí odkaz:
https://doaj.org/article/c8adbf47009e449d893b779aa662c743
Publikováno v:
Sensors, Vol 23, Iss 12, p 5590 (2023)
Cancer is one of the leading causes of death worldwide, and it is well known that an early detection of cancer in a human body will provide an opportunity to cure the cancer. Early detection of cancer depends on the sensitivity of the measuring devic
Externí odkaz:
https://doaj.org/article/c329079cabd5455495a130c471ec2bda
Autor:
Jonathan Phillips
Publikováno v:
Brazilian Political Science Review, Vol 16, Iss 2 (2022)
Few of the facts in ‘Decadent Developmentalism’ will be unfamiliar to even casual followers of Brazil’s political economy: the segmented labour markets that limit workers’ access to social protection; the ability of incumbent firms like JBS t
Externí odkaz:
https://doaj.org/article/8b9b5dfadb484e26a5cd292fd08e69ae
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Multiple sclerosis (MS)-related inflammation can be divided into lesional activity, mediated by immune cells migrating from the periphery to the central nervous system (CNS) and non-lesional activity, mediated by inflammation compartmentalized to CNS
Externí odkaz:
https://doaj.org/article/ffc10dfe3f484b51945dd443dae215fa
Autor:
Santiago Rolon, Christine Huynh, Maya Guenther, Minhal Gardezi, Jonathan Phillips, Ashley L. Gehrand, Hershel Raff
Publikováno v:
Physiological Reports, Vol 7, Iss 24, Pp n/a-n/a (2019)
Abstract Hypoxia is common with preterm birth and may lead to long‐term effects on the adult hypothalamic–pituitary–adrenal (HPA) axis that are sexually dimorphic due to neonatal androgens. Although the adult rat adrenal does not express apprec
Externí odkaz:
https://doaj.org/article/ebfea01220764e978ccad093fb585c3b
Autor:
Kent Miner, Katja Labitzke, Benxian Liu, Paul Wang, Kathryn Henckels, Kevin Gaida, Robin Elliott, Jian Jeffrey Chen, Longbin Liu, Anh Leith, Esther Trueblood, Kelly Hensley, Xing-Zhong Xia, Oliver Homann, Brian Bennett, Mike Fiorino, John Whoriskey, Gang Yu, Sabine Escobar, Min Wong, Teresa L. Born, Alison Budelsky, Mike Comeau, Dirk Smith, Jonathan Phillips, James A. Johnston, Joseph G. McGivern, Kerstin Weikl, David Powers, Karl Kunzelmann, Deanna Mohn, Andreas Hochheimer, John K. Sullivan
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
There is an unmet need in severe asthma where approximately 40% of patients exhibit poor β-agonist responsiveness, suffer daily symptoms and show frequent exacerbations. Antagonists of the Ca2+-activated Cl− channel, TMEM16A, offers a new mechanis
Externí odkaz:
https://doaj.org/article/41d8cbf66f0741758aee1902a2f9ab21