Zobrazeno 1 - 10
of 105
pro vyhledávání: '"P. Jeremy Wang"'
Autor:
Jingjing Zhang, Manickam Gurusaran, Yasuhiro Fujiwara, Kexin Zhang, Meriem Echbarthi, Egor Vorontsov, Rui Guo, Devon F. Pendlebury, Intekhab Alam, Gabriel Livera, Martini Emmanuelle, P. Jeremy Wang, Jayakrishnan Nandakumar, Owen R. Davies, Hiroki Shibuya
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
In meiosis, BRCA2 associates to MEILB2 localising at DNA double-strand breaks (DSBs). Here, the authors identify BRCA2 and MEILB2- associating protein 1 termed BRME1 to work together in regulating meiotic recombination.
Externí odkaz:
https://doaj.org/article/6e679d2b3eb24e0c874ec41bdc538df0
Autor:
Rong Liu, Seth D. Kasowitz, David Homolka, N. Adrian Leu, Jordan T. Shaked, Gordon Ruthel, Devanshi Jain, Huijuan Lin, Scott Keeney, Mengcheng Luo, Ramesh S. Pillai, P. Jeremy Wang
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110110- (2021)
Summary: Mechanisms driving the prolonged meiotic prophase I in mammals are poorly understood. RNA helicase YTHDC2 is critical for mitosis to meiosis transition. However, YTHDC2 is highly expressed in pachytene cells. Here we identify an essential ro
Externí odkaz:
https://doaj.org/article/5e6e1c32c1214f81825e5a7b07b206dd
Autor:
Jessica Y Chotiner, N Adrian Leu, Fang Yang, Isabella G Cossu, Yongjuan Guan, Huijuan Lin, P Jeremy Wang
Publikováno v:
eLife, Vol 12 (2024)
Meiotic progression requires coordinated assembly and disassembly of protein complexes involved in chromosome synapsis and meiotic recombination. Mouse TRIP13 and its ortholog Pch2 are instrumental in remodeling HORMA domain proteins. HORMAD proteins
Externí odkaz:
https://doaj.org/article/0256f45fcbe84407aa849f5a310cbbd1
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
The structure of the leaf microbiome can alter host fitness and change in response to abiotic and biotic factors, like seasonality, climate, and leaf age. However, relatively few studies consider the influence of host age on microbial communities at
Externí odkaz:
https://doaj.org/article/5df4f31be9b74ad39e92d987b867406f
Autor:
Yong-Hyun Shin, Youngsok Choi, Serpil Uckac Erdin, Svetlana A. Yatsenko, Malgorzata Kloc, Fang Yang, P. Jeremy Wang, Marvin L. Meistrich, Aleksandar Rajkovic
Publikováno v:
PLoS Genetics, Vol 7, Iss 2 (2011)
Externí odkaz:
https://doaj.org/article/2921c323ab7e4452b1cd2598b0cfcc71
Autor:
Yongjuan Guan, Hongyan Gao, N Adrian Leu, Anastassios Vourekas, Panagiotis Alexiou, Manolis Maragkakis, Zhenlong Kang, Zissimos Mourelatos, Guanxiang Liang, P Jeremy Wang
Publikováno v:
PLoS Genetics, Vol 19, Iss 5, p e1010566 (2023)
Transposable elements constitute nearly half of the mammalian genome and play important roles in genome evolution. While a multitude of both transcriptional and post-transcriptional mechanisms exist to silence transposable elements, control of transp
Externí odkaz:
https://doaj.org/article/6fb3ccb1c174425a95ff36753cfe0893
Autor:
Natoya J Peart, Taylor A Johnson, Sungkyoung Lee, Matthew J Sears, Fang Yang, Mathieu Quesnel-Vallières, Huijuan Feng, Yocelyn Recinos, Yoseph Barash, Chaolin Zhang, Brian P Hermann, P Jeremy Wang, Christopher B Geyer, Russ P Carstens
Publikováno v:
PLoS Genetics, Vol 18, Iss 9, p e1010416 (2022)
Control over gene expression is exerted, in multiple stages of spermatogenesis, at the post-transcriptional level by RNA binding proteins (RBPs). We identify here an essential role in mammalian spermatogenesis and male fertility for 'RNA binding prot
Externí odkaz:
https://doaj.org/article/53361225d7ba4d6abbf2e4eaf7ec0fd2
Autor:
Lacey R. Lopez, Cassandra J. Barlogio, Christopher A. Broberg, Jeremy Wang, Janelle C. Arthur
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Inflammatory bowel diseases (IBDs) and inflammation-associated colorectal cancer (CRC) are linked to blooms of adherent-invasive Escherichia coli (AIEC) in the intestinal microbiota. AIEC are functionally defined by their ability to adhere/invade epi
Externí odkaz:
https://doaj.org/article/0b4177c944084710a6ea931ab434a746
Publikováno v:
PLoS Genetics, Vol 17, Iss 2, p e1009265 (2021)
Piwi-interacting RNAs (piRNAs) play critical roles in protecting germline genome integrity and promoting normal spermiogenic differentiation. In mammals, there are two populations of piRNAs: pre-pachytene and pachytene. Transposon-rich pre-pachytene
Externí odkaz:
https://doaj.org/article/3652cb17792e47f59a1fba3e30233bcf
Autor:
Esmat Rousta, Akihiko Oka, Bo Liu, Jeremy Herzog, Aadra P. Bhatt, Jeremy Wang, Mohammad B. Habibi Najafi, Ryan Balfour Sartor
Publikováno v:
Nutrients, Vol 13, Iss 10, p 3565 (2021)
Commonly used synthetic dietary emulsifiers, including carboxymethylcellulose (CMC) and polysorbate-80 (P80), promote intestinal inflammation. We compared abilities of CMC vs. P80 to potentiate colitis and impact human microbiota in an inflammatory e
Externí odkaz:
https://doaj.org/article/503385f3342f4b1e8d8d759cacb60321