Zobrazeno 1 - 10
of 15
pro vyhledávání: '"P. J. Wurm"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
The two major scale-up criteria in continuously stirred bioreactors are 1) constant aerated power input per volume (Pg/Vl), and 2) the volumetric O2 mass transfer coefficient (kla). However, Pg/Vl is only influenced by the stirrer geometry, stirrer s
Externí odkaz:
https://doaj.org/article/fb674f43b8fc4ee0b0ab6bb4d2edb526
Publikováno v:
AMB Express, Vol 12, Iss 1, Pp 1-9 (2022)
Key points Development of a flow cytometry (FCM) method for viability determination of S. acidocaldarius using the fluorescent dyes fluorescein diacetate and concanavalin A conjugated with rhodamine. Applicability of the developed method was shown vi
Externí odkaz:
https://doaj.org/article/3c1b6f916d564927a6d8622e35464101
Autor:
Yongtao Han, Elisabeth Georgii, Santiago Priego-Cubero, Christoph J. Wurm, Patrick Hüther, Gregor Huber, Robert Koller, Claude Becker, Jörg Durner, Christian Lindermayr
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Seed dormancy is a crucial developmental transition that affects the adaption and survival of plants. Arabidopsis DELAY OF GERMINATION 1 (DOG1) is known as a master regulator of seed dormancy. However, although several upstream factors of DOG1 have b
Externí odkaz:
https://doaj.org/article/b10bddcc993240579f1dc2a09af626a8
Autor:
Kokilavani Sivaraman, Paco Pino, Guillaume Raussin, Stephanie Anchisi, Charles Metayer, Nicolas Dagany, Julia Held, Sabine Wrenger, Tobias Welte, Maria J. Wurm, Florian M. Wurm, Beata Olejnicka, Sabina Janciauskiene
Publikováno v:
Microorganisms, Vol 11, Iss 11, p 2683 (2023)
Intracellular lipid droplets (LDs) can accumulate in response to inflammation, metabolic stresses, and other physiological/pathological processes. Herein, we investigated whether spike proteins of SARS-CoV-2 induce LDs in human peripheral blood monon
Externí odkaz:
https://doaj.org/article/db2413774549499d9f185926ebfc3649
Autor:
Claudio Counoupas, Paco Pino, Alberto O. Stella, Caroline Ashley, Hannah Lukeman, Nayan D. Bhattacharyya, Takuya Tada, Stephanie Anchisi, Charles Metayer, Jacopo Martinis, Anupriya Aggarwal, Belinda M. Dcosta, Warwick J. Britton, Joeri Kint, Maria J. Wurm, Nathaniel R. Landau, Megan Steain, Stuart G. Turville, Florian M. Wurm, Sunil A. David, James A. Triccas
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT Global control of COVID-19 will require the deployment of vaccines capable of inducing long-term protective immunity against SARS-CoV-2 variants. In this report, we describe an adjuvanted subunit candidate vaccine that affords elevated, sust
Externí odkaz:
https://doaj.org/article/215dbedfcba04207b2b7b97f024ad384
Publikováno v:
Journal of Statistical Software, Vol 99, Iss 1 (2021)
Regularization techniques such as the lasso (Tibshirani 1996) and elastic net (Zou and Hastie 2005) can be used to improve regression model coefficient estimation and prediction accuracy, as well as to perform variable selection. Ordinal regression m
Externí odkaz:
https://doaj.org/article/e8e3c497a41f4e35934bf2e4130a1e33
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2021)
To date, high-pressure homogenization is the standard method for cell disintegration before the extraction of cytosolic and periplasmic protein from E. coli. Its main drawback, however, is low selectivity and a resulting high load of host cell impuri
Externí odkaz:
https://doaj.org/article/ca3fb7276a994272919d2ed685e3a040
Autor:
Christopher L. D. McMillan, Armira Azuar, Jovin J. Y. Choo, Naphak Modhiran, Alberto A. Amarilla, Ariel Isaacs, Kate E. Honeyman, Stacey T. M. Cheung, Benjamin Liang, Maria J. Wurm, Paco Pino, Joeri Kint, Germain J. P. Fernando, Michael J. Landsberg, Alexander A. Khromykh, Jody Hobson-Peters, Daniel Watterson, Paul R. Young, David A. Muller
Publikováno v:
Vaccines, Vol 10, Iss 4, p 578 (2022)
The ongoing coronavirus disease 2019 (COVID-19) pandemic continues to disrupt essential health services in 90 percent of countries today. The spike (S) protein found on the surface of the causative agent, the SARS-CoV-2 virus, has been the prime targ
Externí odkaz:
https://doaj.org/article/047b2bd3483b4cd9b6da0a66f2543ada
Designs and Characterization of Subunit Ebola GP Vaccine Candidates: Implications for Immunogenicity
Autor:
Valentina Agnolon, Divor Kiseljak, Maria J. Wurm, Florian M. Wurm, Charlotte Foissard, Fabrice Gallais, Sarah Wehrle, César Muñoz-Fontela, Laurent Bellanger, Bruno Emanuel Correia, Giampietro Corradin, François Spertini
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The humoral responses of Ebola virus (EBOV) survivors mainly target the surface glycoprotein GP, and anti-GP neutralizing antibodies have been associated with protection against EBOV infection. In order to elicit protective neutralizing antibodies th
Externí odkaz:
https://doaj.org/article/007fe3b6b33a4a30bd1fc66d32a650be
Autor:
Julian Kopp, Stefan Kittler, Christoph Slouka, Christoph Herwig, Oliver Spadiut, David J. Wurm
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Recombinant protein production with Escherichia coli is usually carried out in fed-batch mode in industry. As set-up and cleaning of equipment are time- and cost-intensive, it would be economically and environmentally favorable to reduce the number o
Externí odkaz:
https://doaj.org/article/cb141ed4f8e24e8e882c747741f62b93