Výsledky vyhledávání - "P. J. Szklut"

Leukocyte recruitment into human skin transplanted onto severe combined immunodeficient mice induced by TNF-alpha is dependent on E-selectin

Autor: H C Yan, H M Delisser, J M Pilewski, K M Barone, P J Szklut, X J Chang, T J Ahern, P Langer-Safer, S M Albelda

Publikováno v: The Journal of Immunology. 152:3053-3063

In order to study the in vivo role of E-selectin in human inflammation, we have developed a model in which human skin is transplanted onto severe combined immunodeficient (SCID) mice. The grafted skin closely resembles normal skin and retains its hum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e528d179777b0572c07331d73b2c89b6
https://doi.org/10.4049/jimmunol.152.6.3053

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Inhibition of receptor binding and neutralization of bioactivity by anti-erythropoietin monoclonal antibodies

Autor: A D, D'Andrea, P J, Szklut, H F, Lodish, E M, Alderman

Publikováno v: Blood. 75:874-880

We have generated four high affinity monoclonal antibodies (MoAbs) to recombinant human erythropoietin (EPO). All four MoAbs immunoprecipitate radioiodinated native EPO, and the concentrations of MoAbs required for maximum binding range from 10 nmol/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51736845f3ecc7be4f4ef78e58faaf21
https://doi.org/10.1182/blood.v75.4.874.bloodjournal754874

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Leukocyte recruitment into human skin transplanted onto severe combined immunodeficient mice induced by TNF-alpha is dependent on E-selectin

Autor: H C, Yan, H M, Delisser, J M, Pilewski, K M, Barone, P J, Szklut, X J, Chang, T J, Ahern, P, Langer-Safer, S M, Albelda

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 152(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4a40cd1d83be95ddda7067e4b3487487
https://pubmed.ncbi.nlm.nih.gov/7511636

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Structure-function relationships of interleukin-3. An analysis based on the function and binding characteristics of a series of interspecies chimera of gibbon and murine interleukin-3

Autor: Sara G. Shoemaker, Nancy L. Lin, Virginia C. Broudy, Jeffrey V. Matous, P. J. Szklut, Kenneth Kaushansky, R E VanDyke, M K Pearce, J. D. Aghajanian, E. M. Alderman

Publikováno v: The Journal of clinical investigation. 90(5)

IL-3 is a glycoprotein cytokine involved in the hematopoietic response to infectious, immunologic, and inflammatory stimuli. In addition, clinical administration of recombinant IL-3 augments recovery in states of natural and treatment-related marrow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4511d365a3af363ae0425ab88d6e25
https://pubmed.ncbi.nlm.nih.gov/1385477

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Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype

Autor: D A, Schwinn, J W, Lomasney, W, Lorenz, P J, Szklut, R T, Fremeau, T L, Yang-Feng, M G, Caron, R J, Lefkowitz, S, Cotecchia

Publikováno v: The Journal of biological chemistry. 265(14)

A novel alpha 1-adrenergic receptor subtype has been cloned from a bovine brain cDNA library. The deduced amino acid sequence is that of a 466-residue polypeptide. The structure is similar to that of the other adrenergic receptors as well as the larg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::56e3e3df868b99ccccdb1fde8239b917
https://pubmed.ncbi.nlm.nih.gov/1970822

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