Zobrazeno 1 - 10
of 11
pro vyhledávání: '"P. J. Stover"'
Autor:
Eva M. Stevenson, Sandra Terry, Dennis Copertino, Louise Leyre, Ali Danesh, Jared Weiler, Adam R. Ward, Pragya Khadka, Evan McNeil, Kevin Bernard, Itzayana G. Miller, Grant B. Ellsworth, Carrie D. Johnston, Eli J. Finkelsztein, Paul Zumbo, Doron Betel, Friederike Dündar, Maggie C. Duncan, Hope R. Lapointe, Sarah Speckmaier, Nadia Moran-Garcia, Michelle Premazzi Papa, Samuel Nicholes, Carissa J. Stover, Rebecca M. Lynch, Marina Caskey, Christian Gaebler, Tae-Wook Chun, Alberto Bosque, Timothy J. Wilkin, Guinevere Q. Lee, Zabrina L. Brumme, R. Brad Jones
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here, the authors show in a cohort of people with HIV, COVID mRNA vaccination is followed by a transient boost in a particular profile of HIV-specific T-cell responses and a corresponding decrease in residual HIV RNA – suggesting productive immune
Externí odkaz:
https://doaj.org/article/d9cd2a88e3f64b5bb298b5bf37dbca63
Autor:
Naoki Miura, Hideki Matsumoto, Luc Cynober, Patrick J. Stover, Rajavel Elango, Motoni Kadowaki, Dennis M. Bier, Miro Smriga
Publikováno v:
Nutrients, Vol 13, Iss 6, p 1976 (2021)
Phenylalanine and serine are amino acids used in dietary supplements and nutritional products consumed by healthy consumers; however, the safe level of phenylalanine or serine supplementation is unknown. The objective of this study was to conduct two
Externí odkaz:
https://doaj.org/article/6b4e8e15921e46f3b3dbe5eaa3a582f1
Autor:
Karla Misselbeck, Luca Marchetti, Martha S. Field, Marco Scotti, Corrado Priami, Patrick J. Stover
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Folate-mediated one-carbon metabolism (FOCM) is an interconnected network of metabolic pathways, including those required for the de novo synthesis of dTMP and purine nucleotides and for remethylation of homocysteine to methionine. Mouse mod
Externí odkaz:
https://doaj.org/article/ee1ba554942b4b4387b3ac00e7d20fca
Publikováno v:
Journal of Internal Medicine. 292:587-603
Adult stem cells (SCs) represent the regenerative capacity of organisms throughout their lifespan. The maintenance of robust SC populations capable of renewing organs and physiological systems is one hallmark of healthy aging. The local environment o
Autor:
V Habiyambere, B Dongmo Nguimfack, L Vojnov, N Ford, J Stover, L Hasek, P Maggiore, D Low-Beer, M Pérez Gonzàlez, D Edgil, J Williams, J Kuritsky, S Hargreaves, T NeSmith
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0201341 (2018)
INTRODUCTION:Despite considerable progress, just over half of the 37 million people eligible to start antiretroviral therapy (ART) have accessed treatment and millions of HIV-positive people still do not know their status. With demand for ART continu
Externí odkaz:
https://doaj.org/article/705b00c637364c3c9fd91605878b70f8
Autor:
P. J. Stover, W. P. T. James, Per Ole Iversen, Richard J. Johnson, John R. Speakman, D. C. Wallace, G. Frühbeck
Publikováno v:
Journal of Internal Medicine. 285:533-549
Our understanding of human evolution has improved rapidly over recent decades, facilitated by large-scale cataloguing of genomic variability amongst both modern and archaic humans. It seems clear that the evolution of the ancestors of chimpanzees and
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 4, p e1003544 (2014)
Detailed modeling and simulation of biochemical systems is complicated by the problem of combinatorial complexity, an explosion in the number of species and reactions due to myriad protein-protein interactions and post-translational modifications. Ru
Externí odkaz:
https://doaj.org/article/70cb26f89ccc4d7888124f6d25ea011f
Autor:
J Stover
Publikováno v:
Swiss Medical Weekly, Vol 141, Iss 2930 (2011)
Therapeutic interventions following severe traumatic brain injury (TBI) are substantially influenced by complex and interwoven pathophysiological cascades involving both, local and systemic alterations. Our main duty is to prevent secondary progressi
Externí odkaz:
https://doaj.org/article/d7bf40eaa850469f84bed4e4a05e5db7
Autor:
Donald D Anderson, Patrick J Stover
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5839 (2009)
The three enzymes that constitute the de novo thymidylate synthesis pathway in mammals, cytoplasmic serine hydroxymethyltransferase (SHMT1), thymidylate synthase (TYMS) and dihydrofolate reductase (DHFR) undergo sumoylation and nuclear import during
Externí odkaz:
https://doaj.org/article/f4e15d417454407092931658da9d121f
Publikováno v:
Journal of internal medicine. 284(1)
Understanding the physiological and metabolic underpinnings that confer individual differences in responses to diet and diet-related chronic disease is essential to advance the field of nutrition. This includes elucidating the differences in gene exp