Zobrazeno 1 - 10
of 38
pro vyhledávání: '"P. J. Stambrook"'
Autor:
Jie Fu, Jianhua Ling, Ching-Fei Li, Chi-Lin Tsai, Wenjuan Yin, Junwei Hou, Ping Chen, Yu Cao, Ya’an Kang, Yichen Sun, Xianghou Xia, Zhou Jiang, Kenei Furukawa, Yu Lu, Min Wu, Qian Huang, Jun Yao, David H. Hawke, Bih-Fang Pan, Jun Zhao, Jiaxing Huang, Huamin Wang, E. I. Mustapha Bahassi, Peter J. Stambrook, Peng Huang, Jason B. Fleming, Anirban Maitra, John A. Tainer, Mien-Chie Hung, Chunru Lin, Paul J. Chiao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) develops through step-wise genetic and molecular alterations including Kras mutation and inactivation of various apoptotic pathways. Here, we find that development of apoptotic resistance and metastasi
Externí odkaz:
https://doaj.org/article/c655bcead33042daab28080db2e56eaa
Autor:
Wei Huang, Yuliang Feng, Jialiang Liang, Hao Yu, Cheng Wang, Boyu Wang, Mingyang Wang, Lin Jiang, Wei Meng, Wenfeng Cai, Mario Medvedovic, Jenny Chen, Christian Paul, W. Sean Davidson, Sakthivel Sadayappan, Peter J. Stambrook, Xi-Yong Yu, Yigang Wang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
During early postnatal development in mammals, cardiomyocytes exit the cell cycle, losing their regenerative capacity. Here the authors show that, following myocardial infarction, loss of microRNA-128 promotes cardiomyocyte proliferation and cardiac
Externí odkaz:
https://doaj.org/article/b31199b519cc42139b0e79ff4459abd5
Autor:
Jennifer L Mamrosh, Jae Man Lee, Martin Wagner, Peter J Stambrook, Richard J Whitby, Richard N Sifers, San-Pin Wu, Ming-Jer Tsai, Francesco J DeMayo, David D Moore
Publikováno v:
eLife, Vol 4 (2015)
Externí odkaz:
https://doaj.org/article/7cb0c66bbfc04c7ea1650a865d96bc55
Autor:
Jennifer L Mamrosh, Jae Man Lee, Martin Wagner, Peter J Stambrook, Richard J Whitby, Richard N Sifers, San-Pin Wu, Ming-Jer Tsai, Francesco J DeMayo, David D Moore
Publikováno v:
eLife, Vol 3 (2014)
Chronic endoplasmic reticulum (ER) stress results in toxicity that contributes to multiple human disorders. We report a stress resolution pathway initiated by the nuclear receptor LRH-1 that is independent of known unfolded protein response (UPR) pat
Externí odkaz:
https://doaj.org/article/1cc3ba7a8d1b4fd08d92d37e45f4bf72
Autor:
W G Stetler-Stevenson, P. J. Stambrook, B Birkedal-Hansen, Y Q Li, Z. P. Pavelic, J L Gluckman
Publikováno v:
Oral Diseases. 6:376-382
OBJECTIVE: To compare the frequency of gene expression of matrix metalloproteinases (MMP) stromelysins -1, -2 and -3 (MMP-3, -10, and -11), matrilysin (MMP-7), MT1-MMP (MMP-14), and of TIMPs (Tissue Inhibitors of MMPs) -1, -2, -3 and -4 in head and n
Autor:
M. Lasmar, Nives Zimmermann, C. Sorensen, Z. P. Pavelic, Ljiljana Pavelic, J.J Gluckman, P. J. Stambrook
Publikováno v:
European Journal of Cancer Part B: Oral Oncology. 32:347-351
Oral cavity cancer is a major health concern worldwide. Despite advances in surgery, radiotherapy and chemotherapy over the past 35 years, there has been no significant enhancement in the survival of oral cavity cancer patients. Improved survival wil
Autor:
Z. P. Pavelic, J Pavelic, Koraljka Gall-Trošelj, Hlavka, Krešimir Pavelić, J L Gluckman, P. J. Stambrook
Publikováno v:
ResearcherID
We examined nm23-H1 protein levels in human oligodendrogliomas by immunohistochemistry. This class of brain tumor does not form spontaneous metastases, but its progression from benign (oligodendroglioma) toward malignant phenotype (oligodendroglioma
Publikováno v:
European Archives of Oto-Rhino-Laryngology. 254:S144-S146
Human glutathione S-transferase pi has been known to be a good marker for several tumor types because of the high frequency with which it is overexpressed. In order to determine whether GST pi is useful as an indicator for head and neck cancers, expr
Publikováno v:
Cancer research. 60(13)
Heritable gene silencing is an important mechanism of tumor suppressor gene inactivation in a variety of human cancers. In the present study, we show that methylation-associated silencing of the autosomal adenine phosphoribosyltransferase (Aprt) locu
Autor:
M S, Turker, B M, Gage, J A, Rose, O N, Ponomareva, J A, Tischfield, P J, Stambrook, C, Barlow, A, Wynshaw-Boris
Publikováno v:
Cancer research. 59(19)
The presence of increased frequencies of blood-derived and solid tumors in ataxia-telangiectasia (A-T) patients, coupled with a role for the ATM (A-T mutation) protein in detecting specific forms of DNA damage, has led to the assumption of a mutator