Zobrazeno 1 - 10
of 269
pro vyhledávání: '"P. J. Sharp"'
Autor:
Celine A. Manigbas, Bharati Jadhav, Paras Garg, Mariya Shadrina, William Lee, Gabrielle Altman, Alejandro Martin-Trujillo, Andrew J. Sharp
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Most genetic association studies focus on binary variants. To identify the effects of multi-allelic variation of tandem repeats (TRs) on human traits, we perform direct TR genotyping and phenome-wide association studies in 168,554 individual
Externí odkaz:
https://doaj.org/article/dd07da69aaaa4e69bd9ae62b1c6a5b53
Autor:
Andre Briosa e Gala, Michael T. B. Pope, Milena Leo, Alexander J. Sharp, Abhirup Banerjee, Duncan Field, Honey Thomas, Richard Balasubramaniam, Ross Hunter, Roy S. Gardner, David Wilson, Mark M. Gallagher, Julian Ormerod, John Paisey, Nick Curzen, Timothy R. Betts
Publikováno v:
Journal of Arrhythmia, Vol 40, Iss 5, Pp 1093-1101 (2024)
Abstract Introduction The novel Confirm Rx™ implantable cardiac monitor (ICM) with SharpSense™ technology incorporates a new P‐wave discriminator designed to improve AF detection. This study aimed to evaluate the diagnostic performance of the C
Externí odkaz:
https://doaj.org/article/2230b23da6a64015aff75b2b75ab1575
Autor:
Megan E. Parkinson, Rebecca M. Smith, Karen Tanious, Francesca Curtis, Rebecca Doherty, Lorena Colon, Lucero Chena, Sophie C. Horrocks, Matthew Harrison, Michael B. Fertleman, Melanie Dani, Payam Barnaghi, David J. Sharp, the UK Dementia Research Institute Care Research & Technology Research Group, Lucia M. Li
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Home monitoring systems utilising artificial intelligence hold promise for digitally enhanced healthcare in older adults. Their real-world use will depend on acceptability to the end user i.e. older adults and caregivers. We explo
Externí odkaz:
https://doaj.org/article/20aaeaca983648a98824b77b3ec8285a
Autor:
Samuel J. Dicken, Christina C. Dahm, Daniel B. Ibsen, Anja Olsen, Anne Tjønneland, Mariem Louati-Hajji, Claire Cadeau, Chloé Marques, Matthias B. Schulze, Franziska Jannasch, Ivan Baldassari, Luca Manfredi, Maria Santucci de Magistris, Maria-Jose Sánchez, Carlota Castro-Espin, Daniel Rodríguez Palacios, Pilar Amiano, Marcela Guevara, Yvonne T. van der Schouw, Jolanda M.A. Boer, W.M. Monique Verschuren, Stephen J. Sharp, Nita G. Forouhi, Nicholas J. Wareham, Eszter P. Vamos, Kiara Chang, Paolo Vineis, Alicia K. Heath, Marc J. Gunter, Geneviève Nicolas, Elisabete Weiderpass, Inge Huybrechts, Rachel L. Batterham
Publikováno v:
The Lancet Regional Health. Europe, Vol 46, Iss , Pp 101043- (2024)
Summary: Background: It is unknown whether the association between ultra-processed food (UPF) intake and type 2 diabetes mellitus differs from other degrees of food processing. We examined the association between degree of food processing and inciden
Externí odkaz:
https://doaj.org/article/4aa088a8f2b9484fb8e5247b66d1fcb0
Autor:
David V. Smith, Cooper J. Sharp, Abraham Dachs, James Wyngaarden, Daniel Sazhin, Yi Yang, Melanie Kos, Tia Tropea, Ishika Kohli, John A. Clithero, Ingrid Olson, Tania Giovannetti, Dominic Fareri, Johanna M. Jarcho
Publikováno v:
Data in Brief, Vol 56, Iss , Pp 110810- (2024)
Social relationships change across the lifespan as social networks narrow and motivational priorities shift. These changes may affect, or reflect, differences in how older adults make decisions related to processing social and non-social rewards. Whi
Externí odkaz:
https://doaj.org/article/baea90a66eb5427baa561c7c968b811c
Markerless Motion Capture to Quantify Functional Performance in Neurodegeneration: Systematic Review
Autor:
Julian Jeyasingh-Jacob, Mark Crook-Rumsey, Harshvi Shah, Theresita Joseph, Subati Abulikemu, Sarah Daniels, David J Sharp, Shlomi Haar
Publikováno v:
JMIR Aging, Vol 7, p e52582 (2024)
BackgroundMarkerless motion capture (MMC) uses video cameras or depth sensors for full body tracking and presents a promising approach for objectively and unobtrusively monitoring functional performance within community settings, to aid clinical deci
Externí odkaz:
https://doaj.org/article/73fe56e5aa674df8945661eaae869411
Autor:
Martina Del Giovane, Michael C. B. David, Magdalena A. Kolanko, Anastasia Gontsarova, Thomas Parker, Adam Hampshire, David J. Sharp, Paresh A. Malhotra, Christopher Carswell
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Identifying disease-specific imaging features of idiopathic Normal Pressure Hydrocephalus (iNPH) is crucial to develop accurate diagnoses, although the abnormal brain anatomy of patients with iNPH creates challenges in neuroimaging analysis. We quant
Externí odkaz:
https://doaj.org/article/99445b8a50d743b5972fb3cdcfb00404
Autor:
Charlotte E. Luff, Robert Peach, Emma-Jane Mallas, Edward Rhodes, Felix Laumann, Edward S. Boyden, David J. Sharp, Mauricio Barahona, Nir Grossman
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114274- (2024)
Summary: A signal mixer facilitates rich computation, which has been the building block of modern telecommunication. This frequency mixing produces new signals at the sum and difference frequencies of input signals, enabling powerful operations such
Externí odkaz:
https://doaj.org/article/a76099e9e4584d158a4f4325577f8b47
Autor:
Matthew J Cross, Mathew G Wilson, Simon Kemp, Daniel Friedland, David J Sharp, Thomas D Parker, Karl A Zimmerman, Neil S N Graham, Jessica A Hain, Erin Jane Rooney, Ying Lee, Martina Del-Giovane, Richard J Sylvester
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Introduction Although limited, recent research suggests that contact sport participation might have an adverse long-term effect on brain health. Further work is required to determine whether this includes an increased risk of neurodegenerative diseas
Externí odkaz:
https://doaj.org/article/ab5bc75522d74c1c87e7b35928f1f36c
Autor:
David V. Smith, James Wyngaarden, Cooper J. Sharp, Daniel Sazhin, Ori Zaff, Dominic Fareri, Johanna Jarcho
Publikováno v:
Data in Brief, Vol 53, Iss , Pp 110197- (2024)
Trait reward sensitivity, risk for developing substance use, and mood disorders have each been linked with altered striatal responses to reward. Moreover, striatal response to reward is sensitive to social context, such as the presence of a peer, and
Externí odkaz:
https://doaj.org/article/5dea55caf4034b58a71226e4b5c62206