Zobrazeno 1 - 10
of 255
pro vyhledávání: '"P. J. STERK"'
Publikováno v:
Mediators of Inflammation, Vol 2007 (2007)
Externí odkaz:
https://doaj.org/article/6b176268df8144e99efdc7cc1a6e9fac
Autor:
Valentyna Yasinska, Cristina Gómez, Johan Kolmert, Magnus Ericsson, Anton Pohanka, Anna James, Lars I. Andersson, Maria Sparreman-Mikus, Ana R. Sousa, John H. Riley, Stewart Bates, Per S. Bakke, Nazanin Zounemat Kermani, Massimo Caruso, Pascal Chanez, Stephen J. Fowler, Thomas Geiser, Peter H. Howarth, Ildikó Horváth, Norbert Krug, Paolo Montuschi, Marek Sanak, Annelie Behndig, Dominick E. Shaw, Richard G. Knowles, Barbro Dahlén, Anke-Hilse Maitland-van der Zee, Peter J. Sterk, Ratko Djukanovic, Ian M. Adcock, Kian Fan Chung, Craig E. Wheelock, Sven-Erik Dahlén, Eva Wikström Jonsson, H. Ahmed
Publikováno v:
ERJ Open Research, Vol 9, Iss 5 (2023)
Rationale Patients with severe asthma are dependent upon treatment with high doses of inhaled corticosteroids (ICS) and often also oral corticosteroids (OCS). The extent of endogenous androgenic anabolic steroid (EAAS) suppression in asthma has not p
Externí odkaz:
https://doaj.org/article/a7fc69aad4384962865d87d94aff46ed
Autor:
Nazanin Zounemat Kermani, Woo-Jung Song, Yusef Badi, Ali Versi, Yike Guo, Kai Sun, Pank Bhavsar, Peter Howarth, Sven-Erik Dahlen, Peter J. Sterk, Ratko Djukanovic, Ian M. Adcock, Kian Fan Chung, U-BIOPRED Consortium
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background Patients with severe asthma may have a greater risk of dying from COVID-19 disease. Angiotensin converting enzyme-2 (ACE2) and the enzyme proteases, transmembrane protease serine 2 (TMPRSS2) and FURIN, are needed for viral attachm
Externí odkaz:
https://doaj.org/article/7e30d9684b8b4228a8ed66b954de553c
Autor:
Abilash Ravi, Saheli Chowdhury, Annemiek Dijkhuis, Barbara S. Dierdorp, Tamara Dekker, Rianne Kruize, Yanaika S. Sabogal Piñeros, Christof J. Majoor, Peter J. Sterk, René Lutter
Publikováno v:
ERJ Open Research, Vol 8, Iss 2 (2022)
Background Defective translocation of the translational repressor TIAR (T-cell internal antigen receptor) in bronchial epithelial cells (BECs) from asthma patients underlies epithelial hyperresponsiveness, reflected by an exaggerated production of a
Externí odkaz:
https://doaj.org/article/d194ebe4e82449daa453b4437af136fd
Autor:
Uruj Hoda, Stelios Pavlidis, Aruna T. Bansal, Kentaro Takahashi, Sile Hu, Francois Ng Kee Kwong, Christos Rossios, Kai Sun, Pankaj Bhavsar, Matthew Loza, Frederic Baribaud, Pascal Chanez, Stephen J. Fowler, Ildiko Horvath, Paolo Montuschi, Florian Singer, Jacek Musial, Barbro Dahlen, Norbert Krug, Thomas Sandstrom, Dominic E. Shaw, Rene Lutter, Louise J. Fleming, Peter H. Howarth, Massimo Caruso, Ana R. Sousa, Julie Corfield, Charles Auffray, Bertrand De Meulder, Diane Lefaudeux, Sven‐Erik Dahlen, Ratko Djukanovic, Peter J. Sterk, Yike Guo, Ian M. Adcock, Kian Fan Chung, the U‐BIOPRED study group
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 4, Pp n/a-n/a (2022)
Abstract Background Exacerbation‐prone asthma is a feature of severe disease. However, the basis for its persistency remains unclear. Objectives To determine the clinical and transcriptomic features of frequent exacerbators (FEs) and persistent FEs
Externí odkaz:
https://doaj.org/article/472cffbdc9ba4c16ac2d4d6cd89330da
Autor:
Linsey E. S. de Groot, Dingyu Liu, Barbara S. Dierdorp, Niki Fens, Marianne A. van de Pol, Peter J. Sterk, Wim Kulik, Miriam E. Gerlofs-Nijland, Flemming R. Cassee, Elena Pinelli, René Lutter
Publikováno v:
Environmental Health, Vol 19, Iss 1, Pp 1-10 (2020)
Abstract Background Asthma patients suffer from periodic acute worsening of symptoms (i.e. loss of asthma control or exacerbations), triggered by a variety of exogenous stimuli. With the growing awareness that air pollutants impact respiratory diseas
Externí odkaz:
https://doaj.org/article/fd805339cf214428b826258cf765ecc1
Autor:
Nazanin Zounemat Kermani, Woo-Jung Song, Yusef Badi, Ali Versi, Yike Guo, Kai Sun, Pank Bhavsar, Peter Howarth, Sven-Erik Dahlen, Peter J. Sterk, Ratko Djukanovic, Ian M. Adcock, Kian Fan Chung, U-BIOPRED Consortium
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-3 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/e62d4de4b4f14bd2bb22bcfaf2857760
Autor:
Wangfei Wang, Anirban Sinha, René Lutter, Jie Yang, Christian Ascoli, Peter J. Sterk, Nicole K. Nemsick, David L. Perkins, Patricia W. Finn
Publikováno v:
Viruses, Vol 14, Iss 11, p 2444 (2022)
Asthma symptoms are often exacerbated by the common-cold-causing rhinovirus (RV). In this study, we characterized the temporal behavior of circulating exosomal microRNAs (ExoMiRNAs) in a longitudinal bi-phasic case-control study of mild asthmatics (n
Externí odkaz:
https://doaj.org/article/9ba183b3045e46819dba6ddec762764c
Autor:
Sanaa S. Botros, Samia William, Abdel-Nasser A. Sabra, Naglaa M. El-Lakkany, Sayed H. Seif el-Din, Alfonso García-Rubia, Victor Sebastián-Pérez, Antoni R. Blaazer, Erik de Heuvel, Maarten Sijm, Yang Zheng, Irene G. Salado, Jane C. Munday, Louis Maes, Iwan J.P. de Esch, Geert J. Sterk, Koen Augustyns, Rob Leurs, Carmen Gil, Harry P. De Koning
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 9, Iss , Pp 35-43 (2019)
We report the evaluation of 265 compounds from a PDE-focused library for their antischistosomal activity, assessed in vitro using Schistosoma mansoni. Of the tested compounds, 171 (64%) displayed selective in vitro activity, with 16 causing worm hype
Externí odkaz:
https://doaj.org/article/cdcde76f0d614f8da6d01b3d4b7709e4
Autor:
Job J.M.H. van Bragt, Paul Brinkman, Rianne de Vries, Susanne J.H. Vijverberg, Els J.M. Weersink, Eric G. Haarman, Frans H.C. de Jongh, Sigrid Kester, Annelies Lucas, Johannes C.C.M. in 't Veen, Peter J. Sterk, Elisabeth H.D. Bel, Anke H. Maitland-van der Zee
Publikováno v:
ERJ Open Research, Vol 6, Iss 4 (2020)
Molecular profiling of exhaled breath by electronic nose (eNose) might be suitable as a noninvasive tool that can help in monitoring of clinically unstable COPD patients. However, supporting data are still lacking. Therefore, as a first step, this st
Externí odkaz:
https://doaj.org/article/c7ce607d47cb4c43b5ee15e6c9274687