Zobrazeno 1 - 10
of 656
pro vyhledávání: '"P. J. Nelson"'
Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma
Autor:
Jourdin R. C. Rouaen, Antonietta Salerno, Tyler Shai-Hee, Jayne E. Murray, Giulia Castrogiovanni, Charlotte McHenry, Toni Rose Jue, Vu Pham, Jessica Lilian Bell, Ensieh Poursani, Emanuele Valli, Riccardo Cazzoli, Naomi Damstra, Delia J. Nelson, Kofi L. P. Stevens, Jonathan Chee, Iveta Slapetova, Maria Kasherman, Renee Whan, Francis Lin, Blake J. Cochran, Nicodemus Tedla, Feyza Colakoglu Veli, Aysen Yuksel, Chelsea Mayoh, Federica Saletta, Daniele Mercatelli, Tatyana Chtanova, Arutha Kulasinghe, Daniel Catchpoole, Giuseppe Cirillo, Maté Biro, Holger N. Lode, Fabio Luciani, Michelle Haber, Juliet C. Gray, Toby N. Trahair, Orazio Vittorio
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Anti-disialoganglioside (GD2) antibody therapy has provided clinical benefit to patients with neuroblastoma however efficacy is likely impaired by the immunosuppressive tumor microenvironment. We have previously defined a link between intrat
Externí odkaz:
https://doaj.org/article/c429ada101b14a66a6b9deabd0facbd0
Publikováno v:
Atmospheric Measurement Techniques, Vol 17, Pp 6851-6863 (2024)
In this study, high-resolution radiosondes from the Marine Atmospheric Radiation Measurement (ARM) Global Energy and Water Experiment (GEWEX) Cloud System Study (GCSS) Pacific Cross-section Intercomparison (GPCI) Investigation of Clouds (MAGIC) field
Externí odkaz:
https://doaj.org/article/d6b1af7acc244d8490c661c52f17e0ad
Autor:
Pallavi Sharma, Randy J. Nelson
Publikováno v:
Clocks & Sleep, Vol 6, Iss 3, Pp 446-467 (2024)
Substance use disorder is a major global health concern, with a high prevalence among adolescents and young adults. The most common substances of abuse include alcohol, marijuana, cocaine, nicotine, and opiates. Evidence suggests that a mismatch betw
Externí odkaz:
https://doaj.org/article/16e340a77f864492ac4d5bcd57c42e7f
Autor:
Daniela Rodrigues-Amorim, P. Lorenzo Bozzelli, TaeHyun Kim, Liwang Liu, Oliver Gibson, Cheng-Yi Yang, Mitchell H. Murdock, Fabiola Galiana-Melendez, Brooke Schatz, Alexis Davison, Md Rezaul Islam, Dong Shin Park, Ravikiran M. Raju, Fatema Abdurrob, Alissa J. Nelson, Jian Min Ren, Vicky Yang, Matthew P. Stokes, Li-Huei Tsai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Demyelination is a common pathological feature in a wide range of diseases, characterized by the loss of myelin sheath and myelin-supporting oligodendrocytes. These losses lead to impaired axonal function, increased vulnerability of axons to
Externí odkaz:
https://doaj.org/article/8ebed6b59c0b464ab74100e9c4457c3e
Autor:
Stephen J. Nicholls, Adam J. Nelson, John J. P. Kastelein, Marc Ditmarsch, Andrew Hsieh, Judith Johnson, Danielle Curcio, Douglas Kling, Carol F. Kirkpatrick, Michael H. Davidson
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 6, Pp n/a-n/a (2024)
Abstract Anacetrapib, a cholesteryl ester transfer protein (CETP) inhibitor previously under development, exhibited an usually extended terminal half‐life and large food effect and accumulated in adipose tissue. Other CETP inhibitors have not shown
Externí odkaz:
https://doaj.org/article/6dc8b9af8eaf46bdbcd2ab961d9a1ab2
Publikováno v:
Forensic Science International: Mind and Law, Vol 5, Iss , Pp 100131- (2024)
The insanity defense remains one of the most difficult evaluations for a forensic examiner because it requires a retrospective reconstruction of an individual's mental state and extracting that mental state to specific psycholegal criteria (e.g., cap
Externí odkaz:
https://doaj.org/article/2d4e64469684443ca8159e938862243a
Autor:
Aaron D. Schwab, Todd A. Wyatt, Amy J. Nelson, Angela Gleason, Rohit Gaurav, Debra J. Romberger, Jill A. Poole
Publikováno v:
Journal of Immunotoxicology, Vol 21, Iss 1 (2024)
AbstractEfficacious therapeutic options capable of resolving inflammatory lung disease associated with environmental and occupational exposures are lacking. This study sought to determine the preclinical therapeutic potential of lung-delivered recomb
Externí odkaz:
https://doaj.org/article/2822d7a139e442fb86e7176047ee803e
Autor:
Hao Ye, Carlos Franco, Mostafa A. Aboouf, Markus Thiersch, Semih Sevim, Joaquin Llacer‐Wintle, Andrea Veciana, Gemma Llauradó‐Capdevila, Kaiyuan Wang, Xiang‐Zhong Chen, Qiao Tang, Roc Matheu, Pedro D. Wendel‐Garcia, Pedro A. Sánchez‐Murcia, Bradley J. Nelson, Cong Luo, Josep Puigmartí‐Luis, Salvador Pané
Publikováno v:
Advanced Science, Vol 11, Iss 44, Pp n/a-n/a (2024)
Abstract Covalent Organic Frameworks (COFs) emerged as versatile materials with promising potential in biomedicine. Their customizable functionalities and tunable pore structures make them valuable for various biomedical applications such as biosensi
Externí odkaz:
https://doaj.org/article/973da5b2b1164c5fae8f320e4c91d055
Autor:
Jodi Scholz, Frank J. Secreto, Joan Wobig, Joe Kurian, Clint Hagen, Alexandra Zinnen, Don Vu, Steven J. Johnson, Frank Cetta, Yasir Qureshi, Rachel Reams, Bryan Cannon, Christina M. Heyer, Minhwang Chang, Numrah Fadra, Jennifer Coonen, Heather A. Simmons, Andres Mejia, Jennifer M. Hayes, Puja Basu, Saverio Capuano, Viktoriya Bondarenko, Jeanette M. Metzger, Timothy J. Nelson, Marina E. Emborg
Publikováno v:
Cell Transplantation, Vol 33 (2024)
Cardiac ventricular pressure overload affects patients with congenital heart defects and can cause cardiac insufficiency. Grafts of stem cell–derived cardiomyocytes are proposed as a complementary treatment to surgical repair of the cardiac defect,
Externí odkaz:
https://doaj.org/article/439629bc292c41d8a4faaeffc28551c6
Autor:
Carol L. Bedoya, Eckehard G. Brockerhoff, Lawrence R. Kirkendall, Richard W. Hofstetter, Ximena J. Nelson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Acoustic communication is widespread in beetles, is often sexually dimorphic, and plays a significant role in behaviours such as premating recognition, courtship, and copulation. However, the factors that determine the presence or absence of
Externí odkaz:
https://doaj.org/article/4b7d4327eaac436d9fd8d174576980f7