Zobrazeno 1 - 10
of 28
pro vyhledávání: '"P. J. Neeson"'
Autor:
L. H. Porter, J. J. Zhu, N. L. Lister, S. G. Harrison, S. Keerthikumar, D. L. Goode, R. Quezada Urban, D. J. Byrne, A. Azad, I. Vela, M. S. Hofman, P. J. Neeson, P. K. Darcy, J. A. Trapani, R. A. Taylor, G. P. Risbridger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Chimeric antigen receptor (CAR) T cells have transformed the treatment landscape for hematological malignancies. However, CAR T cells are less efficient against solid tumors, largely due to poor infiltration resulting from the immunosuppress
Externí odkaz:
https://doaj.org/article/eb8dadc0a7e045c7b9cf4a1d7631aa08
Autor:
H. Halse, A. J. Colebatch, P. Petrone, M. A. Henderson, J. K. Mills, H. Snow, J. A. Westwood, S. Sandhu, J. M. Raleigh, A. Behren, J. Cebon, P. K. Darcy, M. H. Kershaw, G. A. McArthur, D. E. Gyorki, P. J. Neeson
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract A prospective study explored the heterogeneous nature of metastatic melanoma using Multiplex immunohistochemistry (IHC) and flow cytometry (FACS). Multiplex IHC data quantitated immune subset number present intra-tumoral (IT) vs the tumor st
Externí odkaz:
https://doaj.org/article/1046ef03187a4802bf52b2ca77c01675
Autor:
Shicheng Sun, Ali Motazedian, Jacky Y. Li, Kevin Wijanarko, Joe Jiang Zhu, Kothila Tharmarajah, Kathleen A. Strumila, Anton Shkaruta, L. Rayburn Nigos, Jacqueline V. Schiesser, Yi Yu, Paul J. Neeson, Elizabeth S. Ng, Andrew G. Elefanty, Edouard G. Stanley
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Arterial endothelial cells (AECs) are the founder cells for intraembryonic haematopoiesis. Here, we report a method for the efficient generation of human haemogenic DLL4+ AECs from pluripotent stem cells (PSC). Time-series single-cell RNA-se
Externí odkaz:
https://doaj.org/article/6b789ce0af934d5d87158dc872de5c71
Autor:
Kelden Richardson, Simon P. Keam, Joe Jiang Zhu, Deborah Meyran, Criselle D’Souza, Sean Macdonald, Kerry Campbell, Michael Robbins, Natalie A. Bezman, Kirsten Todd, Hang Quach, David S. Ritchie, Simon J. Harrison, H. Miles Prince, Joseph A. Trapani, Misty R. Jenkins, Paul A. Beavis, Phillip K. Darcy, Paul J. Neeson
Publikováno v:
Haematologica, Vol 108, Iss 1 (2022)
Patients with refractory relapsed multiple myeloma respond to combination treatment with elotuzumab and lenalidomide. The mechanisms underlying this observation are not fully understood. Furthermore, biomarkers predictive of response have not been id
Externí odkaz:
https://doaj.org/article/330bde42af204d128415d365b42720c4
Autor:
Criselle D’Souza, Simon P. Keam, Han Xian Aw Yeang, Michael Neeson, Kelden Richardson, Andy K. Hsu, Rachael Canfield, Natalie Bezman, Michael Robbins, Hang Quach, David S. Ritchie, Simon J. Harrison, Joseph A. Trapani, H. Miles Prince, Paul A. Beavis, Phillip K. Darcy, Paul J. Neeson
Publikováno v:
Haematologica, Vol 106, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/ffb9fcdcc42040a99e9894fa282c2f05
Autor:
Jessica Li, Sarah Whelan, Maya F. Kotturi, Deborah Meyran, Criselle D’Souza, Kyle Hansen, Spencer Liang, John Hunter, Joseph A. Trapani, Paul J. Neeson
Publikováno v:
Haematologica, Vol 106, Iss 12 (2020)
This study explored the novel immune checkpoint poliovirus receptor- related immunoglobulin domain-containing (PVRIG) in acute myeloid leukemia (AML). We showed that AML patient blasts consistently expressed the PVRIG ligand (poliovirus receptor-rela
Externí odkaz:
https://doaj.org/article/2b005a11c33b42b39ed8bb883feb51b5
Autor:
Thijs W.H. Flinsenberg, Charnelle C. Tromedjo, Nan Hu, Ye Liu, Yin Guo, Kevin Y.T. Thia, Tahereh Noori, Xiaomin Song, Han X. Aw Yeang, Daniela G. Tantalo, Sasanka Handunnetti, John F. Seymour, Andrew W. Roberts, David Ritchie, Rachel Koldej, Paul J. Neeson, Lai Wang, Joseph A. Trapani, Constantine S. Tam, Ilia Voskoboinik
Publikováno v:
Haematologica, Vol 105, Iss 2 (2020)
Externí odkaz:
https://doaj.org/article/558c9b1e21f44feb8a3a2bbe8e5ce1a0
Autor:
Natalie A. Bezman, Amy Jhatakia, Alper Y. Kearney, Ty Brender, Mark Maurer, Karla Henning, Misty R. Jenkins, Amy J. Rogers, Paul J. Neeson, Alan J. Korman, Michael D. Robbins, Robert F. Graziano
Publikováno v:
Blood Advances, Vol 1, Iss 12, Pp 753-765 (2017)
Abstract: Elotuzumab, a humanized monoclonal antibody that binds human signaling lymphocytic activation molecule F7 (hSLAMF7) on myeloma cells, was developed to treat patients with multiple myeloma (MM). Elotuzumab has a dual mechanism of action that
Externí odkaz:
https://doaj.org/article/b48d5441929d44dabeefb1b6238bb93b
Autor:
Katharina Hochheiser, Han Xian Aw Yeang, Teagan Wagner, Candani Tutuka, Andreas Behren, Jason Waithman, Christopher Angel, Paul J Neeson, Thomas Gebhardt, David E Gyorki
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 12, Pp n/a-n/a (2019)
Abstract Objective The immune system can halt cancer progression by suppressing outgrowth of clinically occult micrometastases in a state of cancer‐immune equilibrium. Cutaneous melanoma provides a unique opportunity to study the immune contexture
Externí odkaz:
https://doaj.org/article/9388ac1483874e7d93a5c5ce5f8f912b
Publikováno v:
Cytometry. 36(1)
The finding that lupus anticoagulant (LA) is significantly associated with anti-phosphatidylethanolamine (PE) activity has led to great interest in its relation to the clinical features of the antiphospholipid syndrome (APS). Considerable variability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44abc1ac30c3f3d1f35c106f690c872a
https://pubmed.ncbi.nlm.nih.gov/10331626
https://pubmed.ncbi.nlm.nih.gov/10331626