Zobrazeno 1 - 10
of 16
pro vyhledávání: '"P. J. NEWCOMBE"'
Autor:
Chiara Robba, Elisa R. Zanier, Carmen Lopez Soto, Soojin Park, Romain Sonneville, Raimund Helbolk, Aarti Sarwal, Virginia F. J. Newcombe, Mathieu van der Jagt, Jan Gunst, Tobias Gauss, Samy Figueiredo, Jacques Duranteau, Markus B. Skrifvars, Carolina Iaquaniello, Susanne Muehlschlegel, Victoria Metaxa, Claudio Sandroni, Giuseppe Citerio, Geert Meyfroidt
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-11 (2024)
Abstract Acute brain injuries, such as traumatic brain injury and ischemic and hemorragic stroke, are a leading cause of death and disability worldwide. While characterized by clearly distict primary events—vascular damage in strokes and biomechani
Externí odkaz:
https://doaj.org/article/b1ff6c78df9a4041aa8f609f3d44199b
Autor:
Sophie Richter, Stefan Winzeck, Endre Czeiter, Krisztina Amrein, Evgenios N. Kornaropoulos, Jan Verheyden, Gabriela Sugar, Zhihui Yang, Kevin Wang, Andrew I. R. Maas, Ewout Steyerberg, András Büki, Virginia F. J. Newcombe, David K. Menon, the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Magnetic Resonance Imaging (CENTER-TBI MRI) Sub-study Participants and Investigators
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-7 (2022)
Abstract Background Magnetic resonance imaging (MRI) carries prognostic importance after traumatic brain injury (TBI), especially when computed tomography (CT) fails to fully explain the level of unconsciousness. However, in critically ill patients,
Externí odkaz:
https://doaj.org/article/8cd1891a67a84de7a73363066f4d7ef3
Autor:
Toni J. U. Niiranen, Anne-Cécile Chiollaz, Riikka S. K. Takala, Miko Voutilainen, Olli Tenovuo, Virginia F. J. Newcombe, Henna-Riikka Maanpää, Jussi Tallus, Mehrbod Mohammadian, Iftakher Hossain, Mark van Gils, David K. Menon, Peter J. Hutchinson, Jean-Charles Sanchez, Jussi P. Posti
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundInterleukin 10 (IL-10) and heart fatty acid-binding protein (H-FABP) have gained interest as diagnostic biomarkers of traumatic brain injury (TBI), but factors affecting their blood levels in patients with moderate-to-severe TBI are largely
Externí odkaz:
https://doaj.org/article/859cd7a1291c4551bb9f69a393fd6854
Autor:
Linnéa Lagerstedt, Leire Azurmendi, Olli Tenovuo, Ari J. Katila, Riikka S. K. Takala, Kaj Blennow, Virginia F. J. Newcombe, Henna-Riikka Maanpää, Jussi Tallus, Iftakher Hossain, Mark van Gils, David K. Menon, Peter J. Hutchinson, Henrik Zetterberg, Jussi P. Posti, Jean-Charles Sanchez
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Patients with traumatic brain injury (TBI) exhibit a variable and unpredictable outcome. The proteins interleukin 10 (IL-10) and heart fatty acid-binding protein (H-FABP) have shown predictive values for the presence of intracranial lesio
Externí odkaz:
https://doaj.org/article/5e5cb183aa1244039d93f5ed9cd842ea
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Hi-C and capture Hi-C (CHi-C) are used to map physical contacts between chromatin regions in cell nuclei using high-throughput sequencing. Analysis typically proceeds considering the evidence for contacts between each possible pai
Externí odkaz:
https://doaj.org/article/9e2fffbedae542648467d69bfff083cd
Autor:
Tokhir Dadaev, Edward J. Saunders, Paul J. Newcombe, Ezequiel Anokian, Daniel A. Leongamornlert, Mark N. Brook, Clara Cieza-Borrella, Martina Mijuskovic, Sarah Wakerell, Ali Amin Al Olama, Fredrick R. Schumacher, Sonja I. Berndt, Sara Benlloch, Mahbubl Ahmed, Chee Goh, Xin Sheng, Zhuo Zhang, Kenneth Muir, Koveela Govindasami, Artitaya Lophatananon, Victoria L. Stevens, Susan M. Gapstur, Brian D. Carter, Catherine M. Tangen, Phyllis Goodman, Ian M. Thompson, Jyotsna Batra, Suzanne Chambers, Leire Moya, Judith Clements, Lisa Horvath, Wayne Tilley, Gail Risbridger, Henrik Gronberg, Markus Aly, Tobias Nordström, Paul Pharoah, Nora Pashayan, Johanna Schleutker, Teuvo L. J. Tammela, Csilla Sipeky, Anssi Auvinen, Demetrius Albanes, Stephanie Weinstein, Alicja Wolk, Niclas Hakansson, Catharine West, Alison M. Dunning, Neil Burnet, Lorelei Mucci, Edward Giovannucci, Gerald Andriole, Olivier Cussenot, Géraldine Cancel-Tassin, Stella Koutros, Laura E. Beane Freeman, Karina Dalsgaard Sorensen, Torben Falck Orntoft, Michael Borre, Lovise Maehle, Eli Marie Grindedal, David E. Neal, Jenny L. Donovan, Freddie C. Hamdy, Richard M. Martin, Ruth C. Travis, Tim J. Key, Robert J. Hamilton, Neil E. Fleshner, Antonio Finelli, Sue Ann Ingles, Mariana C. Stern, Barry Rosenstein, Sarah Kerns, Harry Ostrer, Yong-Jie Lu, Hong-Wei Zhang, Ninghan Feng, Xueying Mao, Xin Guo, Guomin Wang, Zan Sun, Graham G. Giles, Melissa C. Southey, Robert J. MacInnis, Liesel M. FitzGerald, Adam S. Kibel, Bettina F. Drake, Ana Vega, Antonio Gómez-Caamaño, Laura Fachal, Robert Szulkin, Martin Eklund, Manolis Kogevinas, Javier Llorca, Gemma Castaño-Vinyals, Kathryn L. Penney, Meir Stampfer, Jong Y. Park, Thomas A. Sellers, Hui-Yi Lin, Janet L. Stanford, Cezary Cybulski, Dominika Wokolorczyk, Jan Lubinski, Elaine A. Ostrander, Milan S. Geybels, Børge G. Nordestgaard, Sune F. Nielsen, Maren Weisher, Rasmus Bisbjerg, Martin Andreas Røder, Peter Iversen, Hermann Brenner, Katarina Cuk, Bernd Holleczek, Christiane Maier, Manuel Luedeke, Thomas Schnoeller, Jeri Kim, Christopher J. Logothetis, Esther M. John, Manuel R. Teixeira, Paula Paulo, Marta Cardoso, Susan L. Neuhausen, Linda Steele, Yuan Chun Ding, Kim De Ruyck, Gert De Meerleer, Piet Ost, Azad Razack, Jasmine Lim, Soo-Hwang Teo, Daniel W. Lin, Lisa F. Newcomb, Davor Lessel, Marija Gamulin, Tomislav Kulis, Radka Kaneva, Nawaid Usmani, Chavdar Slavov, Vanio Mitev, Matthew Parliament, Sandeep Singhal, Frank Claessens, Steven Joniau, Thomas Van den Broeck, Samantha Larkin, Paul A. Townsend, Claire Aukim-Hastie, Manuela Gago-Dominguez, Jose Esteban Castelao, Maria Elena Martinez, Monique J. Roobol, Guido Jenster, Ron H. N. van Schaik, Florence Menegaux, Thérèse Truong, Yves Akoli Koudou, Jianfeng Xu, Kay-Tee Khaw, Lisa Cannon-Albright, Hardev Pandha, Agnieszka Michael, Andrzej Kierzek, Stephen N. Thibodeau, Shannon K. McDonnell, Daniel J. Schaid, Sara Lindstrom, Constance Turman, Jing Ma, David J. Hunter, Elio Riboli, Afshan Siddiq, Federico Canzian, Laurence N. Kolonel, Loic Le Marchand, Robert N. Hoover, Mitchell J. Machiela, Peter Kraft, The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium, Matthew Freedman, Fredrik Wiklund, Stephen Chanock, Brian E. Henderson, Douglas F. Easton, Christopher A. Haiman, Rosalind A. Eeles, David V. Conti, Zsofia Kote-Jarai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Prostate cancer (PrCa) involves a large heritable genetic component. Here, the authors perform multivariate fine-mapping of known PrCa GWAS loci, identifying variants enriched for biological function, explaining more familial relative risk, and with
Externí odkaz:
https://doaj.org/article/36e01625dae94bd89d2103af9c540d34
Autor:
Ruihong Liu, Chuming Chen, Xuefeng Xia, Qijun Liao, Qiong Wang, Paul J. Newcombe, Shuhua Xu, Minghui Chen, Yue Ding, Xiaoying Li, Zhihong Liao, Fucheng Li, Minlian Du, Huaiqiu Huang, Ruimin Dong, Weiping Deng, Ye Wang, Binghui Zeng, Qihao Pan, Danhua Jiang, Hao Zeng, Pak Sham, Yingnan Cao, Patrick H. Maxwell, Zhi-liang Gao, Liang Peng, Yiming Wang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract SLC10A1 codes for the sodium-taurocholate cotransporting polypeptide (NTCP), which is a hepatocellular transporter for bile acids (BAs) and the receptor for hepatitis B and D viruses. NTCP is also a target of multiple drugs. We aimed to eval
Externí odkaz:
https://doaj.org/article/2aa5ad318f384dea9833e704b8fbb7b6
Autor:
Ian Renshaw, Keith Davids, Duarte Araújo, Ana Lucas, William M. Roberts, Daniel J. Newcombe, Benjamin Franks
Publikováno v:
Frontiers in Psychology, Vol 9 (2019)
The recent upsurge in “brain training and perceptual-cognitive training,” proposing to improve isolated processes, such as brain function, visual perception, and decision-making, has created significant interest in elite sports practitioners, see
Externí odkaz:
https://doaj.org/article/6b2c86971dd34f33915d9525ad49f17d
Autor:
James E Peters, Paul A Lyons, James C Lee, Arianne C Richard, Mary D Fortune, Paul J Newcombe, Sylvia Richardson, Kenneth G C Smith
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005908 (2016)
Genome-wide association studies (GWAS) have transformed our understanding of the genetics of complex traits such as autoimmune diseases, but how risk variants contribute to pathogenesis remains largely unknown. Identifying genetic variants that affec
Externí odkaz:
https://doaj.org/article/9f697d5620c9410faac765cfc47510cf
Autor:
Tonny V Veenith, Eleanor Carter, Julia Grossac, Virginia F J Newcombe, Joanne G Outtrim, Victoria Lupson, Guy B Williams, David K Menon, Jonathan P Coles
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65941 (2013)
The aim of these studies was to provide reference data on intersubject variability and reproducibility of diffusion tensor imaging. Healthy volunteers underwent imaging on two occasions using the same 3T Siemens Verio magnetic resonance scanner. At e
Externí odkaz:
https://doaj.org/article/279f520e68544a26aac69edc591fd8d9