Zobrazeno 1 - 10
of 73
pro vyhledávání: '"P. J. Morley"'
Publikováno v:
BMJ Open Quality, Vol 13, Iss 4 (2024)
Background Sepsis is a global healthcare challenge and a leading cause of morbidity and mortality. In the USA, the Centers for Medicare & Medicaid Services has integrated the Severe Sepsis and Septic Shock Management Bundle (SEP-1) into their Core Qu
Externí odkaz:
https://doaj.org/article/288902ca8d1b4dba96a6ce7d26996f19
Publikováno v:
Royal Society Open Science, Vol 11, Iss 10 (2024)
Like many mammals, grasshoppers (infraorder Acrididea) chew using molariform structures. Despite decades of research on mammals, little is known about grasshopper molar form and how it relates to grasshopper feeding biomechanics, diet, dietary ecolog
Externí odkaz:
https://doaj.org/article/95b2e3b592004abc985b379ba88927f7
Autor:
Samuel M. Goodfellow, Robert A. Nofchissey, Valerie J. Morley, Kathryn E. Coan, Kurt C. Schwalm, Joseph A. Cook, Jonathan L. Dunnum, Diane Hanfelt-Goade, Darrell L. Dinwiddie, Daryl B. Domman, Jerry W. Dragoo, Jens H. Kuhn, Steven B. Bradfute
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-10 (2024)
Abstract Orthohantaviruses infect distinct eulipotyphlan and rodent reservoirs throughout the world; some rodent orthohantaviruses can cause disease in humans. In the United States, a primary rodent reservoir for the human-pathogenic Sin Nombre virus
Externí odkaz:
https://doaj.org/article/c53292ce6ef64e2f94ff1f02871c5d55
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Cell-based therapies represent the current frontier of biomedical innovations, with the technologies required underpinning treatments as broad as CAR-T cell therapies, stem cell treatments, genetic therapies and mRNA manufacture. A key bottleneck in
Externí odkaz:
https://doaj.org/article/80e138cf45c0402d85e2a7b20dea8bbe
Autor:
Junping Jing, Laura Bover, C Ian Mockridge, Kerry L Cox, Mark S Cragg, Tatyana Inzhelevskaya, Chris A Penfold, Vikki English, Jane E Willoughby, Hong Shi, Peter J Morley, Heather Jackson, Roopa Srinivasan, Tom Murray, Axel Hoos, Paul Bojczuk, James Smothers, Niranjan Yanamandra, Lang Dou, Sabyasachi Bhattacharya, Laura Seestaller-Wehr, David Kilian, Kui S Voo, Mel John, Heather Niederer, Andrew J Shepherd, Laura Hook, Stephanie Hopley, Sara J Brett, Christopher Hopson, Elaine Paul, Stephen L Martin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background OX40 has been widely studied as a target for immunotherapy with agonist antibodies taken forward into clinical trials for cancer where they are yet to show substantial efficacy. Here, we investigated potential mechanisms of action of anti-
Externí odkaz:
https://doaj.org/article/1d4a1e220c0f453894379600a08cb4a4
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract We introduce a Langevin unravelling of the density matrix evolution of an open quantum system over matrix product states, which we term the time-dependent variational principle-Langevin equation. This allows the study of entanglement dynamic
Externí odkaz:
https://doaj.org/article/215cfa7a781d4013ac5a539c43128859
Autor:
Nicolas J. Walker, Mamunur Rashid, Shirong Yu, Helen Bignell, Casper K. Lumby, Carmen M. Livi, Kate Howell, David J. Morley, Sandro Morganella, Daniel Barrell, Shabhonam Caim, Walraj Gosal, Jens Füllgrabe, Thomas J. Charlesworth, Louella Vasquez, Miika Ahdesmäki, Jordan Eizenga, Parul Prabhat, Vitali Proutski, Marie Laurie Murat-Onana, Catherine J. Greenwood, Lisa Kirkwood, Meeta Maisuria-Armer, Mengjie Li, Emma Coats, Victoria Winfield, Lachlan MacBean, Toby Stock, Alice Tomé-Fernandez, Yat Chan, Nasir Sheikh, Paula Golder, Michael Steward, Tobias W. B. Ost, Douglas Stewart, Albert Vilella, Mojtaba Noursalehi, Benedict Paten, Debora Lucarelli, Joanne Mason, Gareth Ridge, Jason Mellad, Suman Shirodkar, Shankar Balasubaramanian, Joanna D. Holbrook
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Early detection of cancer will improve survival rates. The blood biomarker 5-hydroxymethylcytosine has been shown to discriminate cancer. In a large covariate-controlled study of over two thousand individual blood samples, we created, tested
Externí odkaz:
https://doaj.org/article/d0f8987336da4809bf0d43cd15a3ea02
Autor:
Cosmin A. Bejan, Michael Ripperger, Drew Wilimitis, Ryan Ahmed, JooEun Kang, Katelyn Robinson, Theodore J. Morley, Douglas M. Ruderfer, Colin G. Walsh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Methods relying on diagnostic codes to identify suicidal ideation and suicide attempt in Electronic Health Records (EHRs) at scale are suboptimal because suicide-related outcomes are heavily under-coded. We propose to improve the ascertainme
Externí odkaz:
https://doaj.org/article/6374eb5ac4b94b4d918fe4c505948f43
Autor:
Duneesha De Fonseka, David T. Arnold, Anna J. Morley, Mary Brett, Nidhi Bhatt, Anthony Edey, Richard Daly, Anna C. Bibby, Nick A. Maskell
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background As promising novel treatments develop for malignant pleural mesothelioma (MPM), early prognostication has become increasingly important. Circulating and local inflammatory cells are known to play a significant role in other tumour
Externí odkaz:
https://doaj.org/article/156c695976ce4ed8a37b5cf5fb703eef
Autor:
Stuart D. Burley, H. Tim Breitfeld, David ‘Stan’ Stanbrook, Robert J. Morley, Jochen Kassan, Mohamad Sukarno, D. Wantoro Wantoro
Publikováno v:
The Depositional Record, Vol 7, Iss 1, Pp 111-146 (2021)
Abstract A 2 m thick bed of smectite‐rich clay within a sequence of distal deep water turbidites and marine mudstones of the Temburong Formation on the island of Labuan, Sabah, North‐West Borneo, is an altered, re‐sedimented pyroclastic tuff wh
Externí odkaz:
https://doaj.org/article/ba1924bbf45844afb3fa3c748da21069