Zobrazeno 1 - 10
of 12
pro vyhledávání: '"P. J. Lorimer"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Glioblastoma is the most common type of adult brain tumour and has a median survival after diagnosis of a little more than a year. Glioblastomas have a high frequency of mutations in the TERT promoter and CDKN2A locus that are expected to re
Externí odkaz:
https://doaj.org/article/9600ca8f6ee94a838aaa5c94ff55151b
Autor:
Carole J Proctor, Ian A J Lorimer
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22038 (2011)
Neurodegeneration is an age-related disorder which is characterised by the accumulation of aggregated protein and neuronal cell death. There are many different neurodegenerative diseases which are classified according to the specific proteins involve
Externí odkaz:
https://doaj.org/article/4e64a6a62b90439781a547aaec98936b
Autor:
Ian J Restall, Ian A J Lorimer
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11076 (2010)
BACKGROUND: The molecular chaperone Hsp90 is a promising new target in cancer therapy and selective Hsp90 inhibitors are currently in clinical trials. Previously these inhibitors have been reported to induce either cell cycle arrest or cell death in
Externí odkaz:
https://doaj.org/article/8a56e9a342214aa395e380b66fb8fb23
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2130 (2008)
The signaling pathways that may modulate the pathogenesis of diseases induced by expanded polyglutamine proteins are not well understood.Herein we demonstrate that expanded polyglutamine protein cytotoxicity is mediated primarily through activation o
Externí odkaz:
https://doaj.org/article/ad94c4a9d94048d2bce1d708c0b8826b
Autor:
W. Solomon, P. J. Lorimer
Publikováno v:
Discrete Mathematics. 104:91-97
The Ramsey numbers r ( mK p , n 1 P 2 ,…, n d P 2 ), p >2, are calculated for d p and n j ⩾ m for each j .
Publikováno v:
Equine veterinary journal. Supplement. (36)
Summary Reasons for performing study: Recombinant human erythropoietin (rhuEPO) causes an increase in red blood cell production and aerobic capacity in other species; however, data are lacking on effects in the horse. Hypothesis: This study tested th
Autor:
E. J. Cockayne, P. J. Lorimer
Publikováno v:
Journal of the Australian Mathematical Society. 19:252-256
If G1,…,Gc are graphs without loops or multiple edges there is a smallest integer r(G1,…,Gc) such that if the edges of a complete graph Kn, with n ≧ r(G1,…,Gc), are painted arbitrarily with c colours the ith coloured subgraph contains Gi as a
Autor:
P. J. Lorimer, E. J. Cockayne
Publikováno v:
Canadian Mathematical Bulletin. 18:31-34
Any term or symbol undefined in this paper is defined in [5]. For graphs F and G, G > F means G contains a subgraph isomorphic to F and E(G) denotes the edge set of G. If E ⊆ E(G), 〈E〉 is the subgraph of G whose edge set is E and whose vertex s
Autor:
R. A. Jacobson, K. L. Yocom, S. D. Fisher, M. N. Alexander, P. J. Lorimer, W. H. Richardson, J. E. Joseph, Neal H. McCoy, E. R. Heineman, Marlow Sholander
Publikováno v:
The American Mathematical Monthly. 73:634-649
Autor:
P. J. Lorimer
Publikováno v:
Canadian Journal of Mathematics. 17:353-366
In recent years a number of algebraic characterizations of the groups of Moebius transformations over finite fields have been given in the literature; see (1, 3, 6). H. W. E. Schwerdtfeger has noticed (4) that the group G of Moebius transformations o